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Casandra Hdez-Reyes

@casandrah-r.bsky.social

Plant biologist πŸŒ±πŸ… Interested in transcription factors, gene regulation, synbio and root symbiosis 😊

433 Followers  |  520 Following  |  7 Posts  |  Joined: 23.04.2024  |  2.0409

Latest posts by casandrah-r.bsky.social on Bluesky

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Game changer for cell-based plant genetics: the labs of Caixia Gao & Jin-Long Qiu have developed very efficient self-replicating vectors and they just published a very nice proof-of-concept paper.
#plantscience
www.science.org/doi/10.1126/...

07.10.2025 09:54 β€” πŸ‘ 62    πŸ” 27    πŸ’¬ 1    πŸ“Œ 0
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New method paper:
Bennie Lemmens et al @scilifelab.se describe 3D-SPARK, a super-resolution microscopy method that maps changes in DNA replication nanostructures in response to genetic perturbations or drugs, linking spatial cell biology with DNA synthesis dynamics
www.embopress.org/doi/full/10....

07.10.2025 13:04 β€” πŸ‘ 16    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Nuclear rupture in confined cell migration triggers nuclear actin polymerization to limit chromatin leakage
DDR sensor ATR protects against nuclear envelope rupture via formin phosphorylation inducing F-actin formation
Christos Kamaras et al @grosselab.bsky.social
www.embopress.org/doi/full/10....

22.09.2025 09:04 β€” πŸ‘ 13    πŸ” 7    πŸ’¬ 0    πŸ“Œ 2
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Regulation of YAP activity by nuclear G-actin binding The Yes-associated protein YAP belongs to the TEAD (TEA/ATTS domain) transcriptional co-activators that shuttle between cytoplasm and nuclear compartment. YAP and its paralog TAZ (transcriptional co-a...

Hi all, check out our new preprint where we uncover:"Regulation of YAP activity by nuclear G-actin binding", www.biorxiv.org/cgi/content/...
#actin #YAP/TAZ #transcription #nucleus with help from Sonja-Verena Albers
β€ͺ@archaellum.bsky.social‬

31.07.2025 06:34 β€” πŸ‘ 25    πŸ” 18    πŸ’¬ 3    πŸ“Œ 0

Regulation of glucosylceramide synthase and sphingolipid remodeling in the plant response to phosphate deficiency (Bao Yang , Yan Peng , Guo Zhang , Ruifan Liu , Simin Hao , Yi Ren , Shaoping Lu , Xuemin Wang , Liang Guo) doi.org/10.1093/plce... #PlantScience

27.07.2025 15:42 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
Fig. 7.Proposed model for the role of DNA methylation (DNAme) in the regulation of hypocotyl elongation during thermomorphogenesis in Arabidopsis. DNAme represses expression of SDC to prevent degradation of PIF4, probably by promoting GA-mediated inhibition of DELLA, thereby enhancing warm-induced auxin biosynthesis and hypocotyl growth. In addition, repression of SDC affects other aspects of auxin metabolism in a PIF4-independent manner (dashed orange line). Besides SDC repression, DNAme might also influence additional regulatory pathways to promote temperature-induced hypocotyl growth (dashed gray and black lines).

Fig. 7.Proposed model for the role of DNA methylation (DNAme) in the regulation of hypocotyl elongation during thermomorphogenesis in Arabidopsis. DNAme represses expression of SDC to prevent degradation of PIF4, probably by promoting GA-mediated inhibition of DELLA, thereby enhancing warm-induced auxin biosynthesis and hypocotyl growth. In addition, repression of SDC affects other aspects of auxin metabolism in a PIF4-independent manner (dashed orange line). Besides SDC repression, DNAme might also influence additional regulatory pathways to promote temperature-induced hypocotyl growth (dashed gray and black lines).

β˜€οΈ SPECIAL ISSUE RESEARCH 🌑️

πŸ“– Garro et al. show that non-CG DNA methylation represses SDC expression to regulate auxin & gibberellin-related genes, maintaining hypocotyl elongation in warm temps.

πŸ”— doi.org/10.1093/jxb/...

@maigarro.bsky.social‬ @maticapella.bsky.social‬
#PlantScience πŸ§ͺ

01.07.2025 15:11 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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🀩 BEAUTIFULL highlight of our work by Sabine Muller now published in @currentbiology.bsky.social

πŸ‘‡
doi.org/10.1016/j.cu...

24.06.2025 13:15 β€” πŸ‘ 14    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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YAP maintains the dynamics of TDP-43 condensates and antagonizes TDP-43 pathological aggregates - Nature Cell Biology Zhang et al. show that YAP binds to TDP-43 to promote TDP-43 multimerization and phase separation. YAP and TDP-43 may co-localize in multiple cell types in oxidative stress and in brain samples from i...

www.nature.com/articles/s41...

22.06.2025 21:20 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Nice auditorium β˜€οΈπŸŒΏπŸŒ³

12.06.2025 16:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The rice AT-rich pincer-like element family of conserved noncoding sequences regulates chromatin loop formation (Yonghan Xu , Dechuan Wu , Manman Zhao , Wei Tang , Xiang Cheng , Qunwen Hu , Zhiwei Liu , Jiangtao Gan , et al) doi.org/10.1093/plph... #PlantScience

29.05.2025 16:26 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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Professor Philip Poole elected as Fellow of the Royal Society

We are delighted that Professor Philip Poole has been elected as a Fellow of @royalsociety.org!

Phil’s work focuses on the rhizosphere – a nutrient-rich area which is key in plant productivity – and how bacteria establish symbiotic interactions with plants πŸ‘‡
bit.ly/3H3LvJJ

20.05.2025 10:08 β€” πŸ‘ 21    πŸ” 3    πŸ’¬ 0    πŸ“Œ 3
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Delighted to announce the publication of our new study on N assimilation pathways in Laccaria bicolor & poplar ECM in PlantPhysiology. Special thanks to Feng and Xinyin for their key contributions to this work, which builds upon research I initiated in 1985!

academic.oup.com/plphys/advan...

16.05.2025 08:45 β€” πŸ‘ 26    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1

This goes will with this gem, showing a high-speed AFM-video of a myosin V walking along an actin track.
www.nature.com/articles/nat...
I remember seeing this work at the OIST SPDC 2014 workshop in Okinawa & being blown away. 🀯
#AFM #Cytoskeleton #Actin #Myosin #Microscopy #Bioimaging

07.05.2025 16:38 β€” πŸ‘ 29    πŸ” 5    πŸ’¬ 0    πŸ“Œ 2
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Subfunctionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae | PNAS Biosynthetic gene clusters (BGCs) are sets of often heterologous genes that are genetically and functionally linked. Among eukaryotes, BGCs are mos...

Subfunctionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae

From: www.pnas.org/doi/10.1073/...

#PlantScience #SecMet

05.05.2025 11:30 β€” πŸ‘ 35    πŸ” 14    πŸ’¬ 1    πŸ“Œ 2
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CarboTag: a modular approach for live and functional imaging of plant cell walls - Nature Methods A suite of nontoxic and permeable CarboTag probes in various colors enables live quantitative imaging of a range of plant cell wall characteristics and dynamic, high-resolution mapping of cell wall ch...

πŸ“œ CarboTag: a modular approach for live and functional imaging of plant cell walls

πŸ§‘β€πŸ”¬ Maarten Besten, Joris Sprakel, et al.

πŸ“” @naturemethods.bsky.social

πŸ”— www.nature.com/articles/s41...

#️⃣ #PlantScience #PlantCellWalls #PlantTools #PlantMicroscopy #PlantImaging #PlantMethods

02.05.2025 11:46 β€” πŸ‘ 28    πŸ” 15    πŸ’¬ 0    πŸ“Œ 2
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Illuminating plant metabolism with genetically encoded biosensors The metabolic flexibility of plants enables them to cope particularly well with changing environmental conditions. This flexibility is achieved by cel…

Impressive tour-de-force review article by @stephanwagner.bsky.social and Andreas Meyer @unibonn.bsky.social on the use of genetically encoded biosensors in plants! Fantastic resource, thank you so much for sharing this with the community, Stephan and Andreas!!
www.sciencedirect.com/science/arti...

24.04.2025 10:53 β€” πŸ‘ 23    πŸ” 12    πŸ’¬ 1    πŸ“Œ 0
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Symbiotic plant–bacterial–fungal interaction orchestrates ethylene and auxin signaling for optimized plant growth We provide critical insights into the intricate relationship between plants and their associated microbiota, focusing on two well-characterized plant growth-promoting microbes – Enterobacter sp. SA18....

Symbiotic plant–bacterial–fungal interaction orchestrates ethylene and auxin signaling for optimized plant growth
πŸ¦ πŸ„πŸŒ±Tripartite interaction 😍😍😍

24.04.2025 15:27 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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TaLAC129 is a negative regulator of arbuscular mycorrhizal symbiosis but enhanced the growth and yield of bread wheat This study identifies TaLAC129, a key laccase gene, as a negative regulator of arbuscular mycorrhizal (AM) colonization in wheat. Overexpression of TaLAC129 enhances nutrient uptake efficiency and wh...

Interesting paper, but a yield trial in little flower pots does not convince me of the "agronomic" relevance of these conclusions. I find the wording of this paper quite misleading.

onlinelibrary.wiley.com/doi/10.1111/...

24.04.2025 15:34 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Initiation of Translation in Bacteria and Chloroplasts Relative rates of protein synthesis in bacteria generally depend on the number of copies of a messenger RNA (mRNA) and the efficiency of their loading…

Initiation of Translation in Bacteria and Chloroplasts www.sciencedirect.com/science/arti...

17.04.2025 13:46 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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A Recipe for Complexity: Building the Potato Pan-Genome

Interested in hearing more about the story behind our latest paper?
Check out our blog post and the latest @naturepodcast.bsky.social episode!

πŸ“ go.nature.com/3G73vT7

πŸŽ™οΈ www.nature.com/articles/d41...

16.04.2025 16:01 β€” πŸ‘ 12    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

Looks excellent! πŸ‘ŒπŸ» I’ll give it a try

17.04.2025 06:50 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Low overlap of transcription factor DNA binding and regulatory targets - Nature A near-complete survey of transcription factor activities in Saccharomyces cerevisiae reveals that most transcription factors have both activator and repressor activities and limited overlap between t...

To the top of the "to-read" list. Looks like a heroic amount of work from the Hahn lab (large-scale ChEC-seq compendium!) www.nature.com/articles/s41...

16.04.2025 16:04 β€” πŸ‘ 56    πŸ” 28    πŸ’¬ 3    πŸ“Œ 2
16.04.2025 10:22 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

This is a great Harvard web site highlighting all of the important work underway. ALL Universities should be preparing similar web sites. Running against these Republican clowns? Emphasize that they were fine eliminating all of this research to pay for tax cuts for billionaires

15.04.2025 00:45 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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A plant CLE peptide and its fungal mimic promote arbuscular mycorrhizal symbiosis via CRN-mediated ROS suppression | PNAS CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptides have emerged as key regulators of plant–microbe interactions, including arbuscular mycorr...

www.pnas.org/doi/10.1073/...

15.04.2025 05:07 β€” πŸ‘ 11    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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JΓΌrgen Kleine-Vehn - @kleinevehnlab.bsky.social - Molecular Plant Physiology

β€’ Unraveling plant growth at a subcellular level

03.04.2025 12:55 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Pitter Huesgen - @degradomics.bsky.social - Biochemistry and Functional Proteomics

β€’ Proteomics method development
β€’ Protease substrate identifcation
β€’ Proteolysis in cellular stress responses

03.04.2025 12:55 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Thomas Ott - @ottlab.bsky.social - Plant Cell Biology

β€’ Plant-Microbe Interactions
β€’ Protein organization on cell surfaces
β€’ Membrane-associated signal transduction

03.04.2025 13:15 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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A space for time. Exploring temporal regulation of plant development across spatial scales Developmental timing in plants is tightly regulated at the whole-organism scale, from germination to flowering. Less is known about when and how local transitions are temporally regulated. Not every ...

Our lab's first review article written with @yadhusankar.bsky.social and @vijayalakshmi.bsky.social is out now in The Plant Journal! πŸŽ‰πŸŒ±

We discuss temporal regulation of (plant) development. When and how do plants control organ and cell identity progression?

onlinelibrary.wiley.com/doi/10.1111/...

03.04.2025 09:30 β€” πŸ‘ 96    πŸ” 46    πŸ’¬ 3    πŸ“Œ 2

this one is for you @pareidolia.bsky.social

29.03.2025 15:27 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

@casandrah-r is following 19 prominent accounts