In developing embryos, cells move a lot! Plenty of that movement is random. Is random cell mixing a feature or bug for tissue patterning? Turns out, itβs both! Excited to share the 1st preprint from my postdoc w/ Sean Megason @seanemcgeary.bsky.social and Allon Klein. 1/20 doi.org/10.1101/2025...
24.04.2025 13:18 β π 122 π 34 π¬ 7 π 6
BoltzDesign1: Inverting All-Atom Structure Prediction Model for Generalized Biomolecular Binder Design
Figure 1
Figure 2
Figure 3
BoltzDesign1: Inverting All-Atom Structure Prediction Model for Generalized Biomolecular Binder Design [new]
Protein binder design via model inversion. Distograms optimize structures.
07.04.2025 07:00 β π 8 π 5 π¬ 0 π 0
Drosophila follicle showing retrotransposons (pink & yellow) expressed in somatic cells infecting the oocyte
1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. π§¬
But did you know they can also jump π£π¦π΅πΈπ¦π¦π― cells? π€―
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread π§΅π
17.03.2025 11:56 β π 545 π 259 π¬ 11 π 33
Congratulations James! Some serious modelling here. Cool B-Splines! Great to hear from @lauavinyo.bsky.social after learning from her in the EMBO course for modeling multiCell -> tinyurl.com/2msjm7xm
24.02.2025 14:40 β π 0 π 0 π¬ 0 π 0
Helen Hay Whitney Fellow with Sean Megason at HMS SysBio (PhD w/ Julie Theriot). Biophysicist and quantitative cell biologist, integrating theory and experiment.
Developmental Biologist working at the Francis Crick Institute. Neural tube, morphogens, and gene regulatory networks. Editor-in-chief, Development.
London Β· briscoelab.org
Synthetic developmental biologist at PoL TU Dresden. Cross-species comparison and manipulation of the ORGANOID ZOO.
https://physics-of-life.tu-dresden.de/team/pol-groups/ebisuya
Tweets? from the lab of Dr Jean-Paul Vincent FRS @thecrick.bsky.social. DevBio group celebrating 30 years (!) of research into growth, patterning and apoptosis.
Synthetic biology and systems biology. https://www.elowitz.caltech.edu
How are biological forms encoded? Group leader at IBDM Marseille, director of Turing Center for living systems (CENTURI). Professor at Collège de France, Paris: Dynamics of living systems
Interested in how cells use genes to create shape, form and function in #embryos as well as in Societal Wellbeing
#NotInTheGenes #InNumbersWeTrust #gastruloids #gastrulation
EMBO fellow in the Victora lab at Rockefeller. Previously Moor lab at ETH. All things cell-cell interactions π«§
Chief Science and Strategy Officer, openRxiv. Co-Founder, bioRxiv and medRxiv.
A platform by EMBO that provides independent peer review before journal submission for Refereed Preprints.
Assistant Professor UofT Cell & Systems Biology - ππ π‘ comparative genomics/ethology & evolutionary cell biology of sleep π€ π΄ + adventures with @hilsawh - https://csb.utoronto.ca/faculty/maxwell-shafer/
Scientist studying development of embryos and building their models from stem cells. The author of #TheDanceofLife. Warsaw/Oxford/Cambridge/LA.
donβt play games on my webpage
twitch.tv/eatchain
Professor, UW Biology / Santa Fe Institute
I study how information flows in biology, science, and society.
Book: *Calling Bullshit*, http://tinyurl.com/fdcuvd7b
LLM course: https://thebullshitmachines.com
Corvids: https://tinyurl.com/mr2n5ymk
he/him
π¨π in π¦πΉ Life beyond dogma! Free-floating systems thinker & natural philosopher. Antifragilist extemporanian metamodernist. Open science, society & living [β¦]
[bridged from https://spore.social/@yoginho on the fediverse by https://fed.brid.gy/ ]
A preprint highlights service run by the biological community and supported by The Company of Biologists (@biologists.bsky.social).
π¬πΎπ¨π¦Assistant Professor @uoft.bsky.social Biochemistry, studying the forms and functions of genome organization during development. Canada Research Chair in 4D Genomics. https://sawhlab.netlify.app/
Postdoc @MCB_Harvard/@Biozentrum; PhD @McGillU
PI (Senior Lecturer/Asst. Prof.), University of Haifa.
Gene regulation, RNA biology, systems biology, cell biology.
