Henrico Langeveld

Are these the happiest PhD students in the world? Nature - Brazil, Australia and Italy have the highest satisfaction scores in Nature’s global 2025 PhD survey — but are these nations really the best places to do a doctorate?

We asked 3,785 PhD students across 107 countries about their experiences. Where do you think the happiest doctoral candidates were?

go.nature.com/43usVmf

Polo kinase inhibits protein phosphatase 1 to promote the spindle assembly checkpoint and prevent aneuploidy Protein phosphatase 1 (PP1) is essential for spindle assembly checkpoint (SAC) silencing and mitotic exit, but its regulation during mitosis remains i…

Our latest research in collaboration with @nilssonlab.bsky.social, @andrea-musacchio.bsky.social and Mathieu Bollen reveals a new regulatory strategy employed by cells to control PP1 in mitosis. Check it out in @currentbiology.bsky.social

www.sciencedirect.com/science/arti...

Endogenous structure of antimalarial target PfATP4 reveals an apicomplexan-specific P-type ATPase modulator Nature Communications - Here, the authors present the 3.7 Å cryoEM structure of native sodium efflux pump PfATP4 from Plasmodium falciparum, revealing a bound protein that they term...

Learn how our hunt for the native structure of top antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms.nature.com 👉 rdcu.be/eLRlH 🦠🔬❄️

A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria

These 99 'lab hacks' will make your scientific work easier Nature asked contributors, editors and working researchers to share their best advice for scientists.

some useful tips here

Honoured & grateful to have received an MPM Travel Grant and have the opportunity to present my PhD research at my first MPM 🇺🇸

Amazing science, inspiring discussions & a fantastic community of parasitologists – what a milestone in my journey. @parasitesrule.org
#MPM2025 #Parasitology

What a surreal feeling seeing my first preprint manuscript 🤩🥳
Please go have a look at our “hot off the press” preprint from the Birkholtz Lab where we validate a PfArk1 tool compound and use it to investigate the biological function of PfArk1 during multiple parasite stages

Microscopy preprints - applications in biology - FocalPlane Microscopy preprints - applications in biology - News

📢Our latest preprint list is now up on FocalPlane.
This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included.
focalplane.biologists.com/2025/06/27/m...

🚨 New preprint!
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...

Local scientist recognised A Whyalla local has been nominated as a finalist for the University of Adelaide STEM Award, part of the 7News [...]

Youhooooo @benliffner.bsky.social postdoc work has been highlighted in his local news back in Australia. How amazing is that! I am sure he is inspiring many young Australian to do Science.
whyallanewsonline.com.au/news/2025/06...

New study showing the development of pan-Expansion Microscopy by Morgan et al. @luskinglab.bsky.social to reveal the molecular composition and structural plasticity of individual nuclear pore complexes including LINC complex-dependent dilation. rupress.org/jcb/article/...

Registration and Abstract submission for MPMXXXVI are now open! Abstract submission deadline is June 27th, get yours in quickly. @rmc9z.bsky.social @mjgubbels.bsky.social @omarharb.org
🔗https://www.parasitesrule.com/mpm-xxxvi

Just published, expansion in situ genome sequencing, where you can sequence DNA while still inside the cell, mapping its organization relative to proteins and other markers, with the help of expansion microscopy! Led by @jbuenrostro.bksy.social. www.science.org/doi/10.1126/...

🤩🤩🤩 amazing

Just returned from an incredible week at BioMalPar 🧬🥼🧫🧪 in Germany — a truly memorable experience both scientifically and personally.

Grateful for the opportunity to engage with leading minds in malaria research, forge new connections, and experience the beauty and culture of Germany🇩🇪

De novo designed Hsp70 activator dissolves intracellular condensates Zhang et al. describe computationally designed proteins that modulate Hsp70 ATPase activity. One of these designs refolds proteins, dissolves intracellular condensates, and uncovers their cellular rol...

Discover how Dr. Jason Zhang (@jasonzxzhang.bsky.social) leveraged Cell Press's #MultiJournalSubmission to publish in Cell Chemical Biology: www.cell.com/multi-journa...

Read the full paper "De novo designed Hsp70 activator dissolves intracellular condensates" here: www.cell.com/cell-chemica...

Shared some really exciting science from the Birkholtz Lab on antimalarial drug discovery and P. falciparum biology—spotlight on Aurora kinases.
Thank you @H3D for this opportunity

PS: Yes, that’s me at the back, while being a bit star struck🤩

A graphic showing that 50.6% of research projects with "LGBT" search terms have been cancelled. 45.8% of grants with "transgender" in the search terms have been cancelled. 45.5% of research grants with "vaccine hesitancy" have been cancelled. 3.4% grants with "HIV" or "AIDS" have been cancelled.

The US National Institutes of Health has terminated nearly 800 research projects at a breakneck pace, wiping out significant chunks of funding to entire scientific fields

Read the full story: https://go.nature.com/3EuFRPV

An Essential Adaptor for Apicoplast Fission and Inheritance in Malaria Parasites Blood-stage Plasmodium falciparum parasites rely on a non-photosynthetic plastid, the apicoplast, for survival, making it an attractive target for antimalarial intervention. Like the mitochondrion, th...

🚨 New preprint alert! 🚨
We’ve uncovered a key player in malaria parasite cell division—meet PfAnchor, the first apicoplast-specific dynamin adaptor protein! Check the thread below 🧵for more details. #U_ExM #Malaria #Apicoplast
www.biorxiv.org/content/10.1...

Live-cell super-resolution microscopy reveals how molecules enter and exit the nucleus The nuclear pore complex is the gateway to the nucleus of cells. Now an in vivo imaging technique can track the way in which molecules move through this complex.

An in vivo imaging technique can track the way molecules move through the nucleus

https://go.nature.com/4iXSGAT

Don't panic 😱
#phd #phdstudent #academicsky

Predicting Plasmodium drug resistance through in vitro evolution Knowledge about the resistibility and targets of compounds critically informs antimalarial drug development. Luth et al. systematically analyzed the resistome of Plasmodium falciparum through in vitro...

Of all the -omes neologisms, i think Resistome is my favourite one! www.cell.com/trends/paras...

Would have loved to be able to be there in person, but excited and proud to see a great colleague and a great friend in James Blauwkamp deliver a fantastic PhD Defence!

Been a wonderful experience to see you grow as a scientist over the years and excited to see what's next 🎉
@sabsalon.bsky.social

Stand up for science rally poster standupforscience2025.org

This is a REALLY important thread about the threat to vaccine, vaccine access and vaccine design the new administration is. Do read

Funding for conferences and training – Practical Courses – EMBO Funding for courses that provide training in experimental techniques and promote the transfer of methodologies.

EMBO Practical Courses provide training in experimental techniques. Apply to organize your course by 1 March:
https://www.embo.org/funding/funding-for-conferences-and-training/practical-courses/
#ResearchFunding #LifeSciences 🧪

📣Today-ParaFrap Webinar: Gretchen DIFFENDALL (Team A.Scherf @pasteur.fr): Metabolomics Identifies a Natural Host Cytoadhesion Inhibitor in Asymptomatic #Malaria Cases
@parafrap.bsky.social
Chairperson: A. CLAESSENS @ant1-claessens.bsky.social

🗓️ February 13, 3pm CET

🎟️ bit.ly/ParaFrapWeb

BREAKING: NIH admits funding freeze is illegal, will resume issuing grants An internal memo issued February 12 was obtained by Popular Information.

BREAKING: NIH admits funding freeze is illegal, will resume issuing grants
open.substack.com/pub/populari...

Nobel laureates call on National Academies and biotech CEOs to speak out against Trump attacks on science Nobel laureates are calling on the National Academies and biotech CEOs to speak out against what they see as the Trump administration's attack on science.

Nobel laureates are calling on the National Academies and biotech CEOs to speak out against what they see as the Trump administration's attack on science.

‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.

“The leaders of the Human Genome Project always knew they were just starting a conversation”

The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do

https://go.nature.com/40BeQBh

Researchers rush to preserve federal health databases before they disappear from government websites Journalists have long relied on federal health data for their reporting. We include several tips that they can use to help researchers preserve the data.

“A group of researchers and students at the Harvard T.H. Chan School of Public Health is gathered today for a data preservation marathon, scraping and downloading data related to health equity from U.S. government agency websites before they disappear.”