1 in 5 Greek puppies with chronic kidney disease have advanced liver disease and it is the liver disease that is most linked to poor quality of life
30.08.2025 00:52 β π 5 π 0 π¬ 2 π 0@ebtapper.bsky.social
Hepatologist. #LiverSky / LiverLand. #MedSky. #cirrhosis Academic Chief of Hepatology at University of Michigan. Editor, Hepatology Communications. Kid Chauffeur
1 in 5 Greek puppies with chronic kidney disease have advanced liver disease and it is the liver disease that is most linked to poor quality of life
30.08.2025 00:52 β π 5 π 0 π¬ 2 π 0New at The Lancet Public Health - Targeting alcohol use in high-risk population groups: a US microsimulation study of beverage-specific pricing policies
www.thelancet.com/journals/lan...
#alcohol #LiverSky #MedSky
Dear #LiverSky #HepatoSky researchers:
PSC Partners grant cycle is now open! The deadline for your LOI is December 1, 2025
Need help crafting your grant? I offer editing services to help strengthen your proposal. Let's work together to make your work stand out!
pscpartners.org/research/res...
More #efruxifermin data this time in #MASH F2/F3 fibrosis @ 96 weeks
β
Efficacy w/ dose dependent response (sort of) and NITs consistent
βοΈ not crazy about mITT though it is mentioned no paired bx= non responders
β¬οΈ dose dependent reduction in bone mineral density
#liversky
New hope for #liverhealth: FDA recently approved Wegovy as the 1st #GLP1 therapy for adults with serious #liverdisease. Research presented at TLM β24 demonstrated the groundbreaking treatment potential. Learn more: https://bit.ly/45phv4R
19.08.2025 17:00 β π 2 π 3 π¬ 1 π 0When did I start rounding?
06.08.2025 21:22 β π 10 π 0 π¬ 4 π 0π₯ΎA reboot with endless pearls!
#452 NAFLD/MASLD! Expand your NAFLD/MASLD knowledge!
Expert guest @ebtapper.bsky.social shares his framework for approaching NAFLD/MASLD and the treatment tools he recommends including lifestyle modifications and medications.
www.thecurbsiders.com
my take on procal:
1. zero role in ED, shouldn't be used to start ABX
2. CAN be super helpful in first 24 hr after ICU admit to help disprove sepsis in complex cases (eg aspiration pneumonitis or atelectasis masquerading as PNA). helps stop ABX & redirect.
3. not helpful in limiting ABX duration
π¨ High Yield Infographic Alert!
Elevated PTT? Think bleeding history.
π’ Non-bleeders: APS, contact factor deficiencies, heparin.
π΄ Bleeders: Hemophilias, vWD, factor VIII inhibitors.
Not all prolonged PTTs mean bleeding risk.
#MedEd #Hematology #FOAMed #ElevatedPTT #TheCurbsiders
Another piece of evidence about the role of anticoagulants in cirrhosis. Results of a multicenter effort. The cirroxaban study. @hospitalclinic.bsky.social @idibaps.bsky.social @jhepatology.bsky.social
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
Jaume Bosch
No one, and I mean no one, made more seminal contributions to the measurement, interpretation & clinical applications of HVPG, the prognostic impact of CSPH and its rx.
Truly in the pantheon of all time greatest hepatologists and a kind, generous person on top.
RIP
#liversky
Then, Fred Paffhausen, as of 3pm today I am definitely a dad enjoying perks
19.07.2025 21:31 β π 1 π 0 π¬ 0 π 0Ask my kids what my goals are - though I am consistent, they will tell you the order is reversed
19.07.2025 20:54 β π 0 π 0 π¬ 1 π 0LIFE GOALS
1. Raise happy children
2. Be old dude at grand rounds who falls asleep
Daughter wearing a Jean jacket for our day trip to Canada
19.07.2025 12:01 β π 0 π 0 π¬ 0 π 0I am so sorry for your loss
He was a giant and wonderful man.
I am very sad. My mentor and friend, Jaume Bosch, just has passed away. Thanks for everything, I will miss you. I would always remember our last day together celebrating a journey we begin together @hospitalclinic.bsky.social @idibaps.bsky.social
15.07.2025 18:02 β π 15 π 5 π¬ 2 π 0There was great enthusiasm for βpalliative careβ when it was associated with longer survival in lung cancer
However many of trials launched in its wake wrongly assumed that the consult itself was the active ingredient. For PC to help, the consultant needs proven tools to address the symptoms
doi:10.1001/jamanetworkopen.2025.19426
14.07.2025 00:19 β π 3 π 0 π¬ 1 π 0Wake up new cause of liver enzyme elevation just dropped
09.07.2025 10:41 β π 11 π 4 π¬ 1 π 0They are establishing upper limits of normal for ammonia in pets
Thank you for your attention to this matter!
podcasts.apple.com/us/podcast/l...
Gideon is the best of us.
Truly infectious enthusiasm for hepatology
π management of pbc
π clinical philosophy
π how to build a research career
Recently had @ebtapper.bsky.social on the Critical Care Scenarios podcast talking GI and this topic came up.
icuscenarios.com/lightning-ro...
Cardiovascular risk estimates miss the mark in people with MASH
Heart disease is the most important risk for patients with MASH but the commonly used risk equations just donβt work
New paper in the red journal @amcollegegastro.bsky.social
journals.lww.com/ajg/abstract...
Because the humans make the podcast great
14.06.2025 16:43 β π 4 π 0 π¬ 0 π 0Dear FreelyFiltered
I am a listener of the podcast. I listen for the humans. And their input. I think the AI podcast on the NephJC was a nice as a way for me to hear about a trial and trial discussion I would have missed but the info didnt stick for this adult learner
@kidneyboy.bsky.social
Key points
1. Think about who is at risk for hepatic encephalopathy.
2. Don't anchor on a specific number. Make decisions with the impact on the patient in mind
3. Re-evaluate treatment strategies using patient reported outcomes like quality of life and falls
Here's how I put it together
And if you treat based on poor quality of life you can go back and ask "do you feel better" "are you falling less" and that helps a lot!
(BABS - a score with bilirubin, albumin; OGTT - a physiological test / glutamine challenge)