Steve Persaud, MD, PhD

Streptavidin-drug conjugates streamline optimization of antibody-based hematopoietic stem cell transplant conditioning Key PointsCD45-ADCs with various payloads were compared using a modular SAv-drug conjugate platform, which enabled rapid, efficient ADC screening.The PBD d

This article, recently published in Blood ICT, was accepted through our second look rapid response program. Check it out and consider giving your own research a second chance: ashpublications.org/bloodict/art...

Glad to have had the opportunity to contribute to this commentary describing this important work from Seung Kim’s lab

Streptavidin-drug conjugates streamline optimization of antibody-based hematopoietic stem cell transplant conditioning Hematopoietic stem cell transplantation (HSCT) conditioning using antibody-drug conjugates (ADCs) is a promising approach to preparing patients for tr…

Proud to post the final version of the Persaud Squad's first manuscript-we made a panel of SAv-drug conjugates enabling in-house, cost-effective ADC production from any biotinylated mAb. We compared CD45-ADCs with different payloads as HSCT conditioning agents.

www.sciencedirect.com/science/arti...

After all the damage that tornado caused, seeing this pop of color growing along my walkway is an especially welcome sight

Well that sucks.

Living mostly unscathed by St Louis weather for almost 19 years, I guess I was due (and by the looks of it, pretty damn lucky it wasn’t worse). Hoping everyone else in the area is doing alright.

Tennis player gets caught ripping on her opponent, laments being known hereafter on social media as "Harriet Fart"

YouTube video by Breaking Bad & Better Call Saul Mike Visits Nacho's Family Auto Shop | Cobbler | Better Call Saul

Preparing a colleague for trying to explain anything single-cell/omics to me:
www.youtube.com/watch?v=Mm5a...

Honored to receive a John Hansen Research Grant from @dkms-de.bsky.social to support my research program in minimally toxic stem cell transplant conditioning @washumedicine.bsky.social .

professional.dkms.org/news-events/...

Paas got a little weird with their Easter dye kits this year

“My talk may go a few minutes over time.”
bsky.app/profile/cnn....

YouTube video by CBS Mornings Measles outbreak spreads as experts warn of lasting immune effects

On being asked if Vitamin A or cod liver oil helps with measles, Dr. Celine Gounder’s face at 3:50 is all of us:
m.youtube.com/watch?v=PSwP...

YouTube video by Tom Corson-Knowles Steve Ballmer Runs Around Like A Maniac On Stage (Motivational Presentation)

Barack Obama gets standing ovation at Clippers game while seated next to Steve Ballmer, who’s probably thinking the entire time “you call that a welcome?”
m.youtube.com/watch?v=_WW2...

Damn straight, Southwest inflight app. As it should be.

Ugh…a truly brutal homecoming awaits our return from Honolulu.

Playing conference hooky. Worth it. #Tandem25 #DontTellJohn

ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation ArfGAP2 is a dual regulator of STING signaling and proton efflux in specific cell types, with STING proton channel activity regulating Golgi transit and secretion of cytokines. Autoinflammatory diseas...

A well-deserved shout out to my old friend Subhajit and his coauthors in the Miner lab @pennrheum.bsky.social on their new paper in @cp-cell.bsky.social . You love to see it!

www.cell.com/cell/abstrac...

All aboard the impulse buy express. My pre-conference supply run looks an awful lot like I'm studying for a midterm #Tandem25

Quart-size bag to get through TSA: check. #Tandem25

With all this uncertainty on the federal funding scene, it’s especially sweet starting the day with news of a 3 year foundation grant win. More on the new award very soon!

Good News - email phishers don't seem to be trying anymore

A well-deserved congratulations all around to the 2025 @ash.hematology.org Scholar Award recipients. Particularly proud to see WashU bring home 3 this year! www.hematology.org/newsroom/pre...

A weird and unfortunate coincidence that two of my favorite CD numbers (45 and 47) are also, as of today, the numbers of my least favorite president. What’s next, a return to politics by former senator Christopher “Kit” Bond (“c kit”)?

Great read shared with me by my labmate Dilan. Sound advice for all of us who want to promote “a rising tide that lifts all boats” in academia through mentorship. The 10 rules of the laboratory definitely needs to be a fridge magnet ashpublications.org/ashclinicaln...

My neighborhood theater gets it. Lethal Weapon: Christmas movie.

An interesting keychain we got as a free gift with a purchase - any ideas as to what this red thing is (wrong answers welcome)?

#ASH24 ... it begins. There's gotta be an AI or other algorithm that sees "pathologist" in my member metadata and excludes me from the drug ad flood

Proud to receive a fellowship from @asgct.bsky.social to embark on a brand new project to develop a novel cellular approach to conditioning for hematopoietic stem cell transplants without chemotherapy or irradiation! www.asgct.org/publications...

Off to #ASH24 soon, and once again finding creative ways to blow through leftover pasta sauce before taking off for 5 days

An #ASHHaiku about some new preclinical work in the DiPersio lab, coming soon to an ASH near you:

Anti-kit and SIRP
Transplant sans chemo or rads
Stop by to learn more

ash.confex.com/ash/2024/web...

#ASH24 #bmtsm

YouTube video by Sobel Promotions Ducks Changing Their Minds

No lunch at non-mandatory med student noon seminar

(I held off the lame science memes as long as I could...)

www.youtube.com/watch?v=ygSX...