Bina Singh

While the FIB mills, I doodle…. #MicroscopyHumor #FIBLife #AutoTEM #CryoEM

Delighted to see our work in press! 🙌🔬🧠

Thanks to @glynnca.bsky.social, @michaelgrange.bsky.social and the rest of the fabulous co-authors for all your contributions.

Excited to see where in tissue structural cell biology goes next 👀!

#liftlaughlove #teamtomo #whopper

A rationally designed 2C inhibitor prevents enterovirus D68-infected mice from developing paralysis - Nature Communications There are no vaccines or antivirals available against enterovirus D68. Here, the authors report Jun6504 as a 2C inhibitor and show that it provides broad-spectrum antiviral activity against EV-D68, EV...

"A rationally designed 2C inhibitor prevents enterovirus D68-infected mice from developing paralysis"

www.nature.com/articles/s41...

structure prediction is not science if not experimentally validated. period

Cryogenic Electron Tomography Redefines Herpesvirus Capsid Assembly Intermediates Inside the Cell Nucleus. www.biorxiv.org/content/10.1101/2025.06.27.661840v1 #cryoEM

Just what happens when cryo conditions get too creative: ice contamination feels like sculpture. #CryoFIB #CryoEM #ElectronMicroscopy #MicroscopyArt #MicroscopyMonday

Unveiling the structural spectrum of SARS-CoV-2 fusion by in situ cryo-ET - Nature Communications This study delineates the full sequence of SARS-CoV-2 spike-mediated membrane fusion and shows how S2-targeting antibodies inhibit this process, using a near-native functional fusion system and cryo-e...

"Unveiling the structural spectrum of SARS-CoV-2 fusion by in situ cryo-ET"

www.nature.com/articles/s41...

From disorder to order: cryo-EM reveals RNA-dependent remodeling of Nipah virus polymerase A flurry of recent structural studies have focused on the polymerase complex of the deadly zoonotic pathogen Nipah virus (NiV). These include a report…

My PhD student @rupeshjayachandran.bsky.social wrote a comment piece on recent #nipah virus #polymerase structures, especially the one reported by @salafernanda.bsky.social from the lab of @haukehillen.bsky.social

Please check it out 😊

www.sciencedirect.com/science/arti...