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Rosa Barrio Lab

@rosabarrio1.bsky.social

Ubiquitin-like proteins and Development Lab @ CIC bioGUNE Bilbao Ubiquitin, SUMO, rare diseases, Drosophila, E3 ligases https://www.rosabarriolab.es/ Opinions my own.

746 Followers  |  628 Following  |  24 Posts  |  Joined: 20.08.2024  |  2.0406

Latest posts by rosabarrio1.bsky.social on Bluesky

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πŸ“£ We are moving to Barcelona to join the amazing @crg.eu and explore how centrosomes & cilia work, evolve & respond to the environment. We are looking for
PhD students www.crg.eu/en/content/t...
Postdocs gimm.pt/jobs/postdoc...
Other calls to open, also for an experienced lab manager.
Get in touch!

30.10.2025 13:15 β€” πŸ‘ 91    πŸ” 47    πŸ’¬ 2    πŸ“Œ 3

Fascinated by protein homeostasis, stem cells and development? I am recruiting PhD candidates through the fabulous IMPRS-CellDevoSys program. This place is buzzing with great science and brilliant minds. Come join!

21.10.2025 21:45 β€” πŸ‘ 13    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1

#Drosophila rules! Help us spread the word @drosospain.bsky.social @fly-eds.bsky.social @genetics-gsa.bsky.social @sse-evolution.bsky.social @fly-jedi.bsky.social @flybase.bsky.social @alliancegenome.bsky.social

19.10.2025 10:10 β€” πŸ‘ 8    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
Professor Aga Gambus Professor Aga Gambus

Fully-funded 4-years competitive PhD project in our lab (MIBTP-doctoral-training-programme. p97 unfoldase functions during DNA replication. Open to UK/international candidates. Please get in touch for informal enquiries. Deadline 27th of November. Please share.
warwick.ac.uk/fac/cross_fa...

15.10.2025 08:41 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

congrats to all awardees!

15.10.2025 08:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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#bioGUNE_Talent | πŸŽ‰ Young talent shines!

Three #CICbioGUNE researchers, MartΓ­n, Claudia & MΓ³nica, stand out at 2025 #SEBBMAwards for groundbreaking work in genome editing, liver cancer & protein research. Congratulations!

πŸ”— ow.ly/7ZVt50XaXzi

@sebbm.bsky.social #FundacionBBVA

15.10.2025 06:20 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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We are very pleased to announce our joint meeting with the German @gfeev.bsky.social and the Dutch Developmental Biology Societies, which will take place in Potsdam from the 10-13th of March 2026. Registration is now open! www.uni-potsdam.de/en/gfe-meeti...

06.10.2025 16:21 β€” πŸ‘ 48    πŸ” 29    πŸ’¬ 2    πŸ“Œ 3
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We are hiring ! Interested in understanding how neuronal cell diversity arises? Come and join us @upf.edu for a #PhD #FPI fellowship

06.10.2025 12:59 β€” πŸ‘ 9    πŸ” 11    πŸ’¬ 1    πŸ“Œ 0
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Senior Research Technician at University of Birmingham Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...

07.10.2025 08:51 β€” πŸ‘ 8    πŸ” 13    πŸ’¬ 0    πŸ“Œ 2

Nice meeting you and your team at #EMBOSUMO 2025 in La Grande Motte and get to hear about your projects. Kudos to @guillaumebo6.bsky.social for organization πŸ‘πŸ‘
SUMO rocks!
#SUMO #Ubiquitin #Proteostasis

30.09.2025 11:50 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

#EMBOSUMO is starting! Next few days we will be immersed in the fascinating #SUMO word. Looking forward to it

22.09.2025 11:49 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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πŸ”₯ The #EMBOSUMO workshop kicks off TODAY! πŸŽ‰ Thanks @embo.org @biologists.bsky.social @proteocure.bsky.social @sebiology.bsky.social @newphyt.bsky.social @umontpellier.bsky.social @occitanie.bsky.social for their support. More info: meetings.embo.org/event/25-sum...

22.09.2025 07:45 β€” πŸ‘ 9    πŸ” 5    πŸ’¬ 0    πŸ“Œ 3
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Trump's Harvard cuts threaten a giant in biomedical research: A database about the tiny fruit fly This spring, the Trump administration rescinded a grant that maintained FlyBase, a pillar of global basic research, as part of its broader $2.2 billion funding cuts at Harvard.

The FlyBase situation has made the national news www.nbcnews.com/science/scie...

16.09.2025 13:08 β€” πŸ‘ 28    πŸ” 27    πŸ’¬ 0    πŸ“Œ 1
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Trump's Harvard cuts threaten a giant in biomedical research: A database about the tiny fruit fly This spring, the Trump administration rescinded a grant that maintained FlyBase, a pillar of global basic research, as part of its broader $2.2 billion funding cuts at Harvard.

Loosing #FlyBase / @flybase.bsky.social would be a blow to modern science: an unprecedented information hub combining data across levels of complexity from genes to organisms, reaching out to other species & humans, meticulously reporting on 120 years of research!
www.nbcnews.com/science/scie...

16.09.2025 13:59 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Production and Purification of SUMO-UBC9 and SUMO-RANGAP1CTD SUMOylation is a post-translational modification catalyzed by a multi-step enzymatic cascade. To gain structural biology insights into the last step of this process, where SUMO is transferred from a S...

We are happy to have contributed a protocol to a book on SUMO methods (work mainly by postdoc El Hadji Cisse and engineer StΓ©phane Goffinont): link.springer.com/protocol/10....

01.09.2025 11:53 β€” πŸ‘ 12    πŸ” 5    πŸ’¬ 1    πŸ“Œ 1
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Glad to share the final version of our story about the UBR4 complex, an E4 ligase protein quality control hub @science.org. Now with more cryo-EM structures and a deeper dive into substrate recognition, especially escaped mitochondrial proteins @clausenlab.bsky.social www.science.org/doi/10.1126/...

28.08.2025 18:54 β€” πŸ‘ 80    πŸ” 30    πŸ’¬ 7    πŸ“Œ 1
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Como todos los miΓ©rcoles, recordamos a nuestras colegas afganas y a todas las mujeres y niΓ±as de ese paΓ­s que viven en peligro constante a causa del apartheid al que las somete su propio gobierno. #NoOsOlvidamos.

27.08.2025 07:43 β€” πŸ‘ 2    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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(no title) droso4public is a central resource store supporting science communication and advocacy for Drosophila

Dear GenZ members of the #Drosophila community! You are needed to make cool fly research viral in your social media world! As a boomer I do not understand that sphere, but I can consult and contribute our enormous fund of outreach resources: droso4public.wordpress.com. Please, get in contact!

25.08.2025 10:02 β€” πŸ‘ 23    πŸ” 15    πŸ’¬ 0    πŸ“Œ 1
Dear Fly Community,

In May 2025, the NIH terminated all grant funding to Harvard University, including the NHGRI grant that supported FlyBase. This grant also funded FlyBase teams at Indiana University (IU) and the University of Cambridge (UK), and as a result, their subawards were also canceled.

The Cambridge team has secured support for one to two years through generous donations from the European fly community, emergency funding from the Wellcome Trust, and support from the University of Cambridge. At IU, funding has been secured for one year thanks to reserve funds from Thom Kaufman and a supplement from ORIP/NIH to the Bloomington Drosophila Stock Center (BDSC).

Unfortunately, the situation at Harvard is far more critical. Harvard University had supported FlyBase staff since May but recently denied a request for extended bridge funding. As a result, all eight employees (four full-time and four part-time) were abruptly laid off, with termination dates ranging from August to mid-October depending on their positions. In addition, our curator at the University of New Mexico will leave her position at the end of August. This decision came as a shock, and we are urgently pursuing all possible funding options.

To put the need into perspective: although FlyBase is free to use, it is not free to make. It takes large teams of people and millions of dollars a year to create FlyBase to support fly research (the last NHGRI grant supported us with more than 2 million USD per annum).

To help sustain FlyBase operations, we have been reaching out to you to ask for your support. We have set up a donation site in Cambridge, UK, to which European labs have and can continue to contribute, and a new donation site at IU to which labs in the US and the rest of the world can contribute. We urge researchers to work with their grant administrators to contribute to FlyBase via these sites if at all possible, as more of the money will go to FlyBase. However, we appreciate that some fu…

Dear Fly Community, In May 2025, the NIH terminated all grant funding to Harvard University, including the NHGRI grant that supported FlyBase. This grant also funded FlyBase teams at Indiana University (IU) and the University of Cambridge (UK), and as a result, their subawards were also canceled. The Cambridge team has secured support for one to two years through generous donations from the European fly community, emergency funding from the Wellcome Trust, and support from the University of Cambridge. At IU, funding has been secured for one year thanks to reserve funds from Thom Kaufman and a supplement from ORIP/NIH to the Bloomington Drosophila Stock Center (BDSC). Unfortunately, the situation at Harvard is far more critical. Harvard University had supported FlyBase staff since May but recently denied a request for extended bridge funding. As a result, all eight employees (four full-time and four part-time) were abruptly laid off, with termination dates ranging from August to mid-October depending on their positions. In addition, our curator at the University of New Mexico will leave her position at the end of August. This decision came as a shock, and we are urgently pursuing all possible funding options. To put the need into perspective: although FlyBase is free to use, it is not free to make. It takes large teams of people and millions of dollars a year to create FlyBase to support fly research (the last NHGRI grant supported us with more than 2 million USD per annum). To help sustain FlyBase operations, we have been reaching out to you to ask for your support. We have set up a donation site in Cambridge, UK, to which European labs have and can continue to contribute, and a new donation site at IU to which labs in the US and the rest of the world can contribute. We urge researchers to work with their grant administrators to contribute to FlyBase via these sites if at all possible, as more of the money will go to FlyBase. However, we appreciate that some fu…

https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

Our immediate goals are:

1. To maintain core curation activities and keep the FlyBase website online

2. To complete integration with the Alliance of Genome Resources (The Alliance).

Integration with the Alliance is essential for FlyBase’s long-term sustainability. For nearly a decade, NHGRI/NIH has supported the unification of Model Organism Databases (MODs) into the Alliance, which we aim to achieve by 2028. Therefore, securing bridge funding to sustain FlyBase over the next three years is crucial for successful integration and the long-term access to FlyBase data.

At present, our remaining funds will allow us to keep the FlyBase website online for approximately one more year. Beyond that, its future is uncertain unless new funding is secured. We will, of course, continue pursuing additional grant opportunities as they arise.

Given the uncertainty of future NIH or alternative funding sources, we are relying on the Fly community for support. Your contributions will directly help us retain the staff needed to complete this transition and to secure ongoing fly data curation into the Alliance beyond 2028.

We at FlyBase are incredibly grateful for the outpouring of support from the community during this challenging time. Your encouragement has strengthened our resolve and underscores how vital this resource remains to Drosophila research worldwide.

Sincerely,
The FlyBase Team

https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase Our immediate goals are: 1. To maintain core curation activities and keep the FlyBase website online 2. To complete integration with the Alliance of Genome Resources (The Alliance). Integration with the Alliance is essential for FlyBase’s long-term sustainability. For nearly a decade, NHGRI/NIH has supported the unification of Model Organism Databases (MODs) into the Alliance, which we aim to achieve by 2028. Therefore, securing bridge funding to sustain FlyBase over the next three years is crucial for successful integration and the long-term access to FlyBase data. At present, our remaining funds will allow us to keep the FlyBase website online for approximately one more year. Beyond that, its future is uncertain unless new funding is secured. We will, of course, continue pursuing additional grant opportunities as they arise. Given the uncertainty of future NIH or alternative funding sources, we are relying on the Fly community for support. Your contributions will directly help us retain the staff needed to complete this transition and to secure ongoing fly data curation into the Alliance beyond 2028. We at FlyBase are incredibly grateful for the outpouring of support from the community during this challenging time. Your encouragement has strengthened our resolve and underscores how vital this resource remains to Drosophila research worldwide. Sincerely, The FlyBase Team

The community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n πŸ§ͺ please share

23.08.2025 12:18 β€” πŸ‘ 152    πŸ” 128    πŸ’¬ 1    πŸ“Œ 8

Please please please, if you are able, consider supporting Flybase fiscally. They need our help! I donated this evening. They are in danger of closing and any amount will help. We cannot allow this critical pillar of science to collapse!

23.08.2025 03:07 β€” πŸ‘ 26    πŸ” 22    πŸ’¬ 2    πŸ“Œ 1
FlyBase:Contribute to FlyBase - FlyBase Wiki

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

15.08.2025 12:45 β€” πŸ‘ 128    πŸ” 158    πŸ’¬ 3    πŸ“Œ 26
Esta cuenta apoya a las mujeres afganas

Esta cuenta apoya a las mujeres afganas

Esta cuenta apoya a las mujeres afganas, ΒΏy la tuya? πŸ’œ Han pasado 4 aΓ±os desde que los talibanes les arrebataron todo, pero queremos demostrar que miles de personas en todo el mundo no las olvidan, ΒΏnos ayudas? Β‘Comparte esta imagen! amnistia.es/afganistan

21.08.2025 09:55 β€” πŸ‘ 33    πŸ” 29    πŸ’¬ 0    πŸ“Œ 1

Excited to see this work published online at @cp-cell.bsky.social today!

www.cell.com/cell/fulltex...

20.08.2025 15:20 β€” πŸ‘ 36    πŸ” 17    πŸ’¬ 5    πŸ“Œ 2

David Geier, un mΓ©dico que practicaba la medicina sin licencia en EEUU, es el autor del ΓΊnico estudio que relaciona vacunas con autismo y que es usado por los negacionistas para cargarse la vacunaciΓ³n.

19.08.2025 14:23 β€” πŸ‘ 19    πŸ” 12    πŸ’¬ 2    πŸ“Œ 1

@sebioldev.bsky.social πŸ‘‡

31.07.2025 14:47 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
SEBC – SCQ2025 – XXI Spanish Society of Cell Biology Meeting

We have extended the deadline for early registration to SEBC2025 to September 9th.
Go to sebc2025.org and register to this fantastic meeting and also send your abstract to present your work.
Fantastic lineup of speakers, loads of opportunities to present, interact and have fun

16.07.2025 12:54 β€” πŸ‘ 1    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Targeting SUMOylation triggers interferon-ß-dependent activation of patient and allogenic Natural Killer cells in preclinical models of Acute Myeloid Leukemia Abstract. Natural Killer (NK) cells can play a significant role in the anti-tumoral immune response. In patients with Acute Myeloid Leukemia (AML), NK cells are however often found in low numbers and ...

πŸ“£ Happy to share our last publication on SUMOylation and Natural Killers in AML. aacrjournals.org/mct/article-...

16.07.2025 08:15 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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We've just been awarded a grant to study the cellular basis of regeneration – to track the progenitors of sensory organs in the context of leg regeneration, in our favourite crustacean tinyurl.com/parhyale, based on live imaging and cell tracking. The project involves some cool collaborations... 1/3

13.07.2025 14:54 β€” πŸ‘ 189    πŸ” 39    πŸ’¬ 7    πŸ“Œ 6

Congrats @mirimiam.bsky.social and @cristinapujades.bsky.social for this recognition! @sebioldev.bsky.social

01.07.2025 14:15 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Thrilled to become an EMBO Member! Thanks so much to @embo.org for the recognition, and thanks A LOT to all current and past lab members, mentors and collaborators for making it possible! πŸ€—

01.07.2025 14:04 β€” πŸ‘ 53    πŸ” 5    πŸ’¬ 6    πŸ“Œ 2

@rosabarrio1 is following 20 prominent accounts