The Australian Ubiquitin Summit

‼️For our final invited speaker interview, we talked with the amazing Titia Sixma about her work on the role of ubiquitin in DNA regulation, and some #AusUb2025 highlights. Thank you to everyone who came, it was an amazing conference and a great chance to see the breadth of global ubiquitin research!

‼️Towards the end of #AusUb25, we caught up with Jonathan Pruneda to discuss ubiquitin signalling and its relationship with host-pathogen interactions. It was an amazing conference and such a great chance to meet people from across the ubiquitin field 🤩

‼️ Following on from our “M1 chains everywhere!” session at #AusUb25 we took the chance to interview one of the pioneering researchers in this field, Kazuhiro Iwai. Have a look below! ✨✨✨

‼️It was wonderful to have Professor Kay Hoffmann at the #AusUb25 - and even better to get the chance to interview him! Hear about his experiences in industry and academia as well as his love for proteins😁

‼️Have a listen to a little about Kylie Walter’s exciting new research, conference talk, and her experience at #AusUb2025. What did she enjoy most about the conference?
More interviews to come in the next week so stay tuned 😁

Today we have Brenda Schulman, Director of the Department of Molecular Machines and Signalling at Max Planck Institute of Biochemistry, as our interviewee at #AusUb2025. Jump in to find out her research focus and conference tips!

It’s hard to believe that #AusUb2025 has already come to an end 😢. Don’t worry though - we’ll still be posting our speaker interviews in the next couple of days.

Here’s what Sonja Lorenz thought of the Australian Ubiquitin Summit. 👇

What a fantastic few days at The *inaugural* Australian Ubiquitin Summit 🤩 #UbiquitinByTheBay

It was fun to contribute behind the scenes in the lead-up, help chair the opening session, host lightning talks, and dive into conversations during the poster session and EMCR panel discussions.

We hope that you’ve had a wonderful time at #AusUb2025 at Lorne! Please repost to tell us about your biggest win at #AusUb2025!

Did you make connections🤝?
Learned something exciting💡?
Or spotted rare Aussie flora and fauna🐨🦘?

That was our last presentation session at #AusUb2025!!! 🥳We explored the role of #ubiquitin in different diseases, from cancer to chicken pox.

A huge thank you to our final speakers: Sandra Nicholson, Yi-Ching Wang, Anindita Puri and Ruey-Hwa Chen.

Before we bid goodbye to the beautiful town of Lorne on the Great Ocean Road, make sure to connect with the #AusUb2025 community by following and sharing our page to your connections!

Thank you to our speakers who presented such interesting talks: Titia Sixma, Suhail Nurbhai and Sarah Fritchley (Mission Therapeutics), Malte Gersch, Irina Bezsonova, and Kay Hofmann.

🫣 Can you believe that we are at the last day of #AusUb2025?!?!

The second ‘Mechanisms in #Ubiquitination’ session had a focus on deubiquitinases #DUB.

The #EMCR discussion panel wrapped up Day 3 at #AusUb2025 nicely!

If you are a PI, what would be your best advice to the EMCR you? Let us know in the comment!

The last session during the #TPD day at #AusUb2025 explored the Translational Journey of TPD. Gwenn Hansen and Kanae Gamo both gave great talks on the topic.

While the presentations of the day are all finished, the long anticipated EMCR panel discussion is coming next!

#ubiquitin

Thank you to all speakers: Hsueh-Chi Sherry Yen, Selina Zhang, Benedikt Kessler, Mengying Zhou, and Fumiaki Ohtake.

#ubiquitin #targetedproteindegradation

And that’s our third session of the #TPD day at #AusUb2025 done! Great talks on the forefront of #TPD in Disease Management.

Min Zhuang from ShanghaiTech University talking about the MARCHF5 mitochondria and peroxisome localised E3

#AusUb2025 #LorneUbiquitin2025 @ausub.bsky.social

Very nice presentation by Phil Chamberlain from Neomorph to kick off the TPD day today at @ausub.bsky.social #AusUb2025 #LorneUbiquitin2025

From the fundamentals of glues to identifying more in the proteome to glue

Learning more about cryptic interaction areas of CRBN during glue binding presented by Lei Liu from Tsinghua University @tsinghuauniversity.bsky.social

Work partially in a pre-print @biorxivpreprint.bsky.social

#AusUb2025 #LorneUbqiuitin2025
@ausub.bsky.social

We’ll soon be releasing exclusive interviews with #AusUb2025 speakers! Spread the word so that no one misses out on top tips from our star speakers.

Continuing on with our TPD-themed day at #AusUb2025, we just had amazing talks on ‘the Frontiers of Innovation in TPD’ from Eric Fischer, Fleur Ferguson, Johannes Yeh, Man Pan, and Mikihiko Naito.
#ubiquitin #TPD #targetedproteindegradation

Watch this space for updates on our upcoming EMCR lunch and panel discussion which is bound to be exciting - even some of the Aussie wildlife seem keen to join 😆

Day 3 is TPD day at #AusUb2025. We’ve gone off to a flying start with tantalising talks on molecular glues and PROTACs given by Philip Chamberlain, Lei Liu, Nishma Gupta and Stefan Knapp.

Time to find out what’s the newest insight on the #ubiquitin-proteosome degradation system from our speakers: Shang-Te (Danny) Hsu, Yasushi Saeki, Indrajit Sahu, and Kylie Walters.

While this is our last talk session of Day 2 at #AusUb2025, science goes on at the poster session…

Make sure to check out their posters later today during the poster session!

Congratulations to all speakers: Kouta Nakadai, Xiaoying (Charlotte) Yu, Alina Thielen, Hikaru Tsuchiya, Mai Morita, Mihaela Ficu, Jie Liu, @Sonia Shah, Gwendoline Marbach, and Che Stafford.

And that's our #AusUb2025 Lightning Teaser Talks over in a flash! #ubiquitin

Get excited for the next session at #AusUb2025 which features Lightening Teaser Talks from selected poster presenters!

Another session that’s full of star speakers! Thank you Eric Bennet, Pei Yee Tey, Achim Werner, Xiaofeng Zheng and Min Zhuang for your wonderful presentations!