Maximiliano José Nigro

I was not completely convinced of the «Position-independence» because the heterotopia seems to abide to rostrocaudal and mediolateral axes of cell types, connectivity and function as the cortex above. Hence the «organization-independence»

This is the most interesting paper I have read in a while. The organization of a neural system (nucleus, layer or whatever) does not matter for function as long as it contains the right cell types connected the right way. Thanks to @gquattrocolo.bsky.social for inviting me to her Journal Club

Caricature of Wallace, including the words “After you, Mr. Darwin, kind sir.” By David Hughes for the New Yorker.

Alfred Russel Wallace born OTD in 1823.

He said he shared with Darwin “an intense interest in … the variety [of living things] that catches the eye of the observer even among those which are very much alike, but which are soon found to differ in several distinct characters.”

🌱🐋🧪 #HistSTM #EvoBio

[(Diversity in the Neuronal Machine: Order and Variabil… Discover and share books you love on Goodreads.

I just started this nice book by Ivan Soltesz. I found out about it by chance after a brief chat with Ariel Agmon and I am so happy to find Ernst Mayr all over a book on the diversity of interneurons!

#neuroskyence

www.goodreads.com/book/show/19...

Barbeint i Amazonas: historien om Alfred Russel Wallace Darwinisme har alle hørt om. Men få er klar over at Dar…

Veldig interessant bok om Alfred Russel Wallace. Boken forteller om de forskjellige sider av en veldig interessant mann som oppdaget naturlig utvalg, ble opptatt med spiritisme og med sosiale problemer

www.goodreads.com/book/show/71...

This afternoon’s journal club took me and my kid to the Gulf of Mexico
We think that the term «interaction» is an understatement

#Onthisday was published On the origin of the species by Charles Darwin
I get inspired by this book every time I read it
#evolution
#neuroskyence

#QuattrocoloLab preprint out 👇! We explored changes in the proteome of hippocampal and dentate gyrus growth cones at early postnatal stages. We see that at P1 growth cones from the two subregions are very similar, but start to diverge from P3, with HP growth cones maturing earlier then DG ones.

The writing style is so understated compared to today’s claims. But also: we just send an idea, please publish while we work on the data.
The paper by Cobbs and Comfort describes the role played by Franklin.

This week I am sharing what I think to be the most significant publication in biology since 1859. This paper opened the door to molecular biology and molecular genetics.

#neuroskyence

The family coat of arms made at school by my son features birdwatching. I did get something right so far
@gquattrocolo.bsky.social

Developmental neuroscientists please keep inviting @gquattrocolo.bsky.social to your conferences. She is a great speaker and her lab is doing very interesting research. Plus she has great taste for presents to her husband when she returns from those conferences

In today’s lecture on microcircuit organization we will go through the classics from Penfield to Eccles and get to cell type specific optogenetics to dissect circuits for top down modulation of vision
How neurons connect to compute with a reminder to their biophysical properties
#neuroskyence

It’s a very good episode that makes justice to Buffon. I was surprised at first since he went a bit forgotten. They even mentioned his evolutionary ideas!

By far its birds, but I am far from a decent photographer

From the series “Once upon a time…the discoverers” an episode about Buffon and the concept of deep time
#evolution

All Nobel Prizes 2025 The Nobel Prizes are awarded to those that have conferred the greated benefit to humankind.

Immunology is such a beautiful field! It was just recognized with another Nobel prize.
Richard Lewontin included it (“mechanisms of self-recognition”) in the five properties defining living organisms.
#biology
#neuroskyence

www.nobelprize.org/all-nobel-pr...

No I found the PDF online

To honor the memory of Dr Jane Goodall I am sharing her 1963 article for National Geographic Magazine
#neuroskyence

A pioneer of science, conservation and education who left a long lasting legacy.
Dr Jane Goodall
#neuroskyence

Short philosophical summary for the lecture on Touch
#neuroskyence

This looks like a promising step forward that improves quality rather than quantity
Looking forward to dig in more!

Grilling on a gorgeous fall evening while enjoying a wonderful Zinfandel. A present from the last master student graduated from the lab. The joys of teaching…

Recruitment of GABAergic Interneurons in the Barrel Cortex during Active Tactile Behavior Neural computation involves diverse types of GABAergic inhibitory interneurons that are integrated with excitatory (E) neurons into precisely structur…

www.sciencedirect.com/science/arti...

pubmed.ncbi.nlm.nih.gov/25533350/

A Corticothalamic Circuit for Refining Tactile Encoding Pauzin and Krieger find that L6 corticothalamic (CT) neurons change how the brain evaluates sensory stimuli. Response accuracy is increased (decrease in false positives) at the expense of decreasing r...

I noticed that in a few studies with pipettes (loose patch) spikes are often positive

www.cell.com/cell-reports...

This is very interesting. I am always terrified by extracellular recordings and Neuropixels have aggravated my anxiety. So I really appreciate studies like this.
#neuroskyence

Basket cells, parvalbumin expressing or fast-spiking neurons, names that emphasize different properties of the same type. However they are not all the same, like these in the mouse barrel cortex: one has axon in its layer; the other sends axon to other layers
Both are very beautiful
#neuroskyence

Congratulations to @seanfw.bsky.social and team! Very interesting project leveraging large scale models to make sense of the even larger scale anatomical diversity across regions and species

Congratulations!

Interesting passage. Buffon starts with a jab at the idea of classification by means of reducing beings to an ideal form. Are we, cell typers, exaggerating in splitting the transcriptomic dendrograms?
This reminds me of Agmon’s review

pubmed.ncbi.nlm.nih.gov/39091993/

#neuroskyence
#evolution