Davi Bock

Good read.

Want to use the massive MICrONS dataset for your own research? We understand the challenges and we are here to support you. Submit your proposals for our Proofreading and Annotation program: Virtual Observatory of the Cortex (VORTEX) by August 15. microns-explorer.org/vortex

With @megyounger.bsky.social's lab, et al., we present the first connectomics work in the disease-vector mosquito Aedes aegypti, revealing how its brain is wired to detect host cues.

Preprint: doi.org/10.1101/2025...

#Neuroscience #Connectomics #vEM #VectorBiology 🧪

... curious to see if this one weird trick to recoup tariffs on scientific equipment actually works!
tl;dr the UN Florence agreement says that scientific equipment (under certain conditions) may enter free of duty www.trade.gov/statutory-im...

I think the "embodiment" of this connectome is going to be such a hit: For instance take the interactive "body part" maps on Codex, where you can simply click on your favorite external or visceral part and it will show you all of the neurons associated it! codex.flywire.ai/app/body_par...

Recurrent connectivity supports carbon dioxide sensitivity in Aedes aegypti mosquitoes The mosquito Aedes aegypti′s human host-seeking behavior depends on the integration of multiple sensory cues. One of these cues, carbon dioxide (CO2), gates odorant and heat pathways and activates hos...

New preprint from @darbly.bsky.social‬ @briandepasquale.bsky.social‬ and my labs! If you love (or hate) mosquitoes, have a look:

doi.org/10.1101/2025...

We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟

Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution Understanding the evolution of the bilaterian brain requires a detailed exploration of the precise nature of cellular and subcellular differences between related species. We undertook an electron micr...

Happy to share our publication - Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution www.science.org/doi/10.1126/...

nice shot :)

a baby wearing a black space racer shirt ALT: a baby wearing a black space racer shirt

Preprint Alert! Walking mostly feels natural and easy to us - but the neuronal control of walking is actually incredibly complex. We leveraged the fruit fly as a genetically tractable animal model with a compact nervous system to ask how the brain controls walking direction: tinyurl.com/flywalk. 🧵..

I have told my children this phenomenon is just a glitch in the matrix, and not to worry overmuch. The thing usually reappears later :)

What does a neural network look like? Maybe like this view of Larissa Heinrich's U-net for organelle segmentation, with edges between layer inputs and outputs.

Want to help build networks like this? Join #HHMIJanelia's new AI initiative as a data engineer:
hhmi.wd1.myworkdayjobs.com/en-US/Extern...

Research Specialist - Tavakoli Lab Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute’s Janelia Research Campus is a pio...

🧠 Excited by synapse-level brain mapping? Join us at a world-class institute to build molecular tools based on our new #LICONN work — and push the frontier of #MolecularConnectomics. Let’s decode the brain, one synapse at a time.

hhmi.wd1.myworkdayjobs.com/en-US/Extern...

“The connectome shows that LT52 is anatomically positioned to inhibit the neural networks involved in steering toward a visual object in the environment. Thus, we suggest that LT52 functions to prevent the fly from steering toward its own leg.”

nice 😁

scanning electron micrograph of a Platynereis larva showing a close-up of the prototroch ciliary band

Happy to be involved in UNICIL, our new Wellcome Trust Discovery project coordinated by @micromotility.bsky.social

We will study ciliary dynamics across scales and organisms. A long-term #postdoc position will be available at Heidelberg University […]

[Original post on biologists.social]

Go Zhihao! 😄

High quality ultrastructure and imaging in this dataset. Well done.

Connectomic reconstruction from hippocampal CA3 reveals spatially graded mossy fiber inputs and selective feedforward inhibition to pyramidal cells The mossy fiber (MF) connections to pyramidal cells in hippocampal CA3 are hypothesized to participate in pattern separation and memory encoding, yet no large–scale neuronal wiring diagram exists for ...

Excited to share a connectomics dataset of hippocampus CA3.
Explore the dataset: pyr.ai
Paper introducing the dataset and some of our discoveries: www.biorxiv.org/content/10.1...

Jhereg by Steven Brust might suit

looks like whole committee is heading toward level-funding NSF (thanks for this thread @dangaristo.bsky.social!) bsky.app/profile/dang...

True story. Amazing pommeau and dry ciders. Where @robertmarc.bsky.social’s palette and scientific acumen combine. Really something.

Thanks for having me Bryan. A great pleasure indeed. Plus seeing a Thagomizer in situ was truly cool! :)

Subcommittee Markup of the Commerce, Justice, Science, and Related Agencies Appropriations Act | United States Senate Committee on Appropriations United States Senate Committee on Appropriations

During the subcommittee markup of the Commerce, Justice, Science, and Related Agencies, Sen. Jerry Moran (R-KS) announced that the bill contains 33.9 billion for science agencies (NASA & NSF) which would keep funding steady. ~8 min mark. Full meeting tomorrow.

Full Committee Markup of Commerce, Justice, Science; Agriculture, Rural Development, FDA; and Legislative Branch Appropriations Acts | United States Senate Committee on Appropriations United States Senate Committee on Appropriations

keeping my eye on this Senate committee meeting tomorrow, which will AFAIK will be congress's first response to White House's proposed ~60% NSF budget cut: www.appropriations.senate.gov/hearings/ful...

A logo of a volume EM "cube" of data on a stylised computer monitor with wires extending from the side. Text below reads "CCP-volumeEM - Collaborative Computational Project for Volume Electron Microscopy"

🚨 SAVE THE DATE 🚨
Inaugural CCP-volumeEM Community Meeting, 3rd November 2025 at @crick.ac.uk in London
"Towards a collaborative computational community for volume EM"
Timings: 12pm - 5.30pm, followed by networking reception

#volumeEM #BioImageAnalysis #VEM #CCPvolumeEM #CoSeC

that’s awesome

bsky.app/profile/trev...

A scalable, all-optical method for mapping synaptic connectivity with cell-type specificity https://www.biorxiv.org/content/10.1101/2025.06.25.661552v1

Help us record firefly flashes! 👇🙏

NEW: NSF will be kicked out of their building. Announcement will be made tomorrow by HUD Sec. and Governor of VA. HUD will take over the NSF building over the next two years.

NSF staffer: "There is no planning for NSF, no identified future location, appropriation for a new building or a move."

Proud to share our latest paper. doi.org/10.1016/j.cr...

Through the dedication of @glynnca.bsky.social and @cryingem.bsky.social we report a thorough method to image molecular organisation within hippocampus tissue.

Structural biology in tissue is well and truly here!

@rosfrankinst.bsky.social

Graphical abstract of linked paper. Nematode towers are found in nature on rotten fruit. These towers respond to touch and can attach to insects for collective dispersal.

Wild Nematodes have been observed forming "living towers" on rotting fruit. These tiny worms are not just making acrobatic towers; they’re hitching rides on insects to explore new territories! 🧪

www.cell.com/current-biol...