Jimmy Lee

📢 @bayraktarlab.bsky.social & colabs at @sangerinstitute.bsky.social are assembling the @opentargets.org funded Neuroimmune Team 🧠🧬-Leverage AI to uncover neurodegeneration

Tech Spec: sanger.wd103.myworkdayjobs.com/en-US/Wellco...
Postdoc AI: sanger.wd103.myworkdayjobs.com/en-US/Wellco...

Very excited to see this work comes out ad preprint! An elegant strategy discovering novel recessive signals in Exome sequencing dataset of the British South Asian population 🧬
#bioinformatics #exome #DNA #datascience #genomics #genetics

Amazing work and congratulations Lisa! We have a project asking exactly this question, so would definitely give it a try!!

Analyzing your single-cell data by mapping to a reference atlas? Then how do you know the mapping actually worked, and you’re not analyzing mapping-induced artifacts? We developed mapQC, a mapping evaluation tool www.biorxiv.org/content/10.1... from the ‪@fabiantheis lab. Let’s dive in🧵

Amazing work by the GBM-SPACE team atlassing one of the deadliest cancers #glioblastoma at multimodality, & coupled the elegant scDORI framework.
These studies reveal a high-resolution spatiotemporal cell trajectory from tumour heterogeneity & plasticity at both cellular and molecular levels

Ever wondered what a snapshot of single-cell/spatial dataset can reveal?
scCellFie - a scalable tool that goes beyond gene expression, making metabolic analysis possible
3-2-1, Say GENES 🤳
PREPRINT: doi.org/10.1101/2025...
DOWNLOAD: sccellfie.readthedocs.io
#DataScience #Bioinformatics #Spatial

We are delighted to announce a new collaboration between HCA and @UNESCO.org to help advance open science, global capacity and ethical frameworks to deliver the benefits of genomics at a global scale.

www.humancellatlas.org/news/the-hum...

Absolutely over the moon to share our COVID-19 study is now featured on
@naturecomms.bsky.social
Editors’ Highlights for Microbiology & Infectious Diseases! Huge thanks to
Sonja Schmid for choosing our work as one of the 50 BEST papers in this field. 💡Check it out: www.nature.com/collections/...

If you have experience in sc/spatial transcriptomics with an interest in microbes....come and join our team as a computational postdoc:
sanger.wd103.myworkdayjobs.com/WellcomeSang...

Incredibly exciting datasets on host-microbe interactions in the lung.

Pls RT and reach out if you are interested.

Thrilled to share our new @naturecomms.bsky.social study with @sam-n-barnett.bsky.social on early vs late #COVID19 lung damage 🫁.
Using single-cell & histopathology-informed #SpatialTranscriptomics, we uncovered key biomarkers & immune patterns. Thanks to collaborators, UKCIC & @humancellatlas.org

Absolutely Amazing!!

It was a pleasure to give a talk at the #HCA2024Asia @humancellatlas.org meeting. I really enjoyed catching up with some @sangerinstitute.bsky.social alumni and had some fascinating discussions with amazing scientists!!

#HumanCellAtlas #Neuroscience #SingleCell #Bioinformatics

An integrated transcriptomic cell atlas of human neural organoids - Nature A human neural organoid cell atlas integrating 36 single-cell transcriptomic datasets shows cell types and states and estimates transcriptomic similarity between primary and organoid counterparts, sho...

The integrated transcriptomic cell atlas of human neural #organoids, Barbara Treutlein's lab, @fabiantheis.bsky.social @graycamplab.bsky.social @sergiuppasca.bsky.social @giorgiaquadrato.bsky.social and colleagues:
www.nature.com/articles/s41...