Iswar Hariharan's Avatar

Iswar Hariharan

@hariharanlab.bsky.social

Growth, regeneration and cancer biology. Fascinated by nature.

1,027 Followers  |  259 Following  |  11 Posts  |  Joined: 17.10.2023  |  1.3258

Latest posts by hariharanlab.bsky.social on Bluesky

My PhD work from @hariharanlab.bsky.social is finally out in @dev-journal.bsky.social! We investigated an interesting paradox: how can reduced function of the adhesion molecule Echinoid (Ed) cause seemingly opposite phenotypes—overgrowth and elimination—in different contexts? (1/8)

07.08.2025 22:25 — 👍 9    🔁 6    💬 2    📌 0
Fig.3. echinoid clones are generated and then die, especially when more wild-type tissue is present. (A-F) Wing discs containing GFP-marked clones expressing either UAS-w-RNAi (A,C,E) or UAS-ed-RNAi (B,D,F). Heat shocks of 12 min (A,B), 15 min (C,D) and 30 min (E,F) generate clones at progressively higher density. Scale bar in H applies to H-K. Scale bar in A applies to A-F.

Fig.3. echinoid clones are generated and then die, especially when more wild-type tissue is present. (A-F) Wing discs containing GFP-marked clones expressing either UAS-w-RNAi (A,C,E) or UAS-ed-RNAi (B,D,F). Heat shocks of 12 min (A,B), 15 min (C,D) and 30 min (E,F) generate clones at progressively higher density. Scale bar in H applies to H-K. Scale bar in A applies to A-F.

The cell-adhesion molecule Echinoid promotes tissue survival and separately restricts tissue overgrowth.

Read this #OA Research Article by Danielle Spitzer
@dspitzer.bsky.social , William Sun, Anthony Rodríguez-Vargas, and Iswar Hariharan:

journals.biologists.com/dev/article/...

07.08.2025 13:20 — 👍 5    🔁 3    💬 1    📌 1
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….just as a pair of Forster’s Terns are hunting over the adjoining bay.

11.05.2025 03:23 — 👍 4    🔁 0    💬 0    📌 0
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A pair of United Airlines planes (Boeing 737-900 and Airbus A321-neo) landing on parallel runways at SFO…

11.05.2025 03:23 — 👍 3    🔁 0    💬 1    📌 0
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Black oystercatcher!

05.05.2025 01:15 — 👍 7    🔁 1    💬 0    📌 0
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Starling feeding a big insect to the juvenile

05.05.2025 00:38 — 👍 3    🔁 0    💬 0    📌 0
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This alarm clock cannot be adjusted for the time change! Good thing is that when she tries to wake me up tomorrow it will already be 6.30 am and not 5.30 am.

09.03.2025 03:53 — 👍 2    🔁 0    💬 0    📌 0
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A purple-rumped sunbird in her amazingly-constructed nest.

10.01.2025 14:50 — 👍 1    🔁 0    💬 0    📌 0

Single cell transcriptomics of X-ray irradiated Drosophila wing discs reveals heterogeneity related to cell-cycle status and cell location https://www.biorxiv.org/content/10.1101/2024.12.10.627868v1

12.12.2024 14:34 — 👍 3    🔁 1    💬 0    📌 0
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CONGRATULATIONS TO GUKESH, THE NEW WORLD CHAMPION 🏆

The 18-year-old Indian star has defeated the reigning champion, Ding Liren, to become the youngest-ever undisputed classical chess world champion. Wow! 🇮🇳

12.12.2024 13:04 — 👍 267    🔁 110    💬 12    📌 27
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After walking one mile up a steep street this morning, this sign struck a chord.

07.12.2024 21:55 — 👍 13    🔁 0    💬 0    📌 0
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Happy New Year!!! Spent part of today photographing Sandhill cranes.

02.01.2024 02:40 — 👍 3    🔁 0    💬 0    📌 0
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Sandhill cranes in flight. Staten Island, California.

24.12.2023 22:59 — 👍 2    🔁 0    💬 0    📌 0
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Today is the 136th birth anniversary of the amazing mathematician Srinivasa Ramanujan - celebrated as National Mathematics Day in India. Maybe every country should have their own National Mathematics Day.

22.12.2023 17:10 — 👍 5    🔁 2    💬 0    📌 0
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My first post on Bluesky. Appropriately, a Great BLUE Heron.

19.12.2023 05:24 — 👍 15    🔁 2    💬 1    📌 0

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