DFG-funded HyperMet Research Unit (FOR 5795)

How Weight Lifting Took Over America

What a great video on the history of weight lifting and reasons for its current popularity in the US by the New York Times!
www.nytimes.com/2026/02/02/w...

Are you working in sports medicine or exercise physiology and wish to present at a cost-effective conference in a nice location? Submit your abstract for the German Congress of Science in Sports Medicine September 24th and 25th 2026 in Tübingen! Please RT
www.medizin.uni-tuebingen.de/de/science-i...

Sometimes simple things are game changers. By correcting for mortality that is not ageing related (e.g., accidents), the heritablity estimate for longevity increases to aoround 55%. #Longevity
www.science.org/doi/epdf/10....

On the 12th of March 2026, 15-16 h Munich time, Shalender Bhasin, Harvard, will present on testosterone. He is the authority on testosterone and has just published a review in Nature Metabolism on it (www.nature.com/articles/s42...). The link is here: tum-conf.zoom-x.de/j/6649072772...

Join the Munich longevity symposium with Chiara Herzog and Tony Wyss-Coray on the 25th of February in Munich for free. Please register here: collab.dvb.bayern/x/oCpugw In person only! #longevity

Exercise (MVPA) is king for lifespan www.thelancet.com/action/showP...

It is really amazing how easy it is to become a longevity expert!

Yesterday we had our bi-annual "state of TUM exercise biology" review and adjusted our mission statement.

Great news! Today we heard that the DFG will fund the expensive aging biomarker analyses of the TauAge longevity trial with Tony Wyss Coray and Chiara Herzog clinicaltrials.gov/study/NCT066...

In our mh.tum.de/en/mh/academ... we have a module on evidence-based training for performance, fitness, and health. Today we visited the Olympic training centre Bavaria to learn about elite sports support. Thanks to its head Volker Herrmann for introducing us and taking questions!

Looking forward to discussing the vLamax/vLapeak with Andy Jones and Katha Dunst at the @ecssofficial.bsky.social meeting in Lausanne!

How fasting boosts breast cancer therapy A discovery in mice reveals why fasting enhances a type of breast cancer treatment — a hormone-signalling pathway and gene-expression changes have key roles.

A discovery in mice reveals why fasting enhances a type of breast cancer treatment

go.nature.com/4oUCGCk

Listen to one of the legends of myokine research this Thursday,the 18.12., but only at a Australia-Europe-friendly time of 9 am (Munich time): tum-conf.zoom-x.de/j/6219384334...

Looking forward to present the first @hypermet.bsky.social data at the 18th SCWD meeting in Rome!

Looking forward to going to Rome today for the cachexia, sarcopenia & wasting disorder conference to meet colleagues and to represent HyperMet!

Congratulations to Sakke Mäntiselkä, Juha Hulmi and other Jyväskylä colleagues for getting this HyperMet-related paper into the Monthly Collection of the Best APS Research Articles!

Munich people, we will organise this in person longevity symposium on the 25th of February 2026. Register here: collab.dvb.bayern/x/oCpugw

We are delighted that Troy Hornberger will give a talk this Thursday 15 h Munich time on “Visualizing the Sites of Mechanically Induced Growth in Skeletal Muscle”. The Zoom link is:
tum-conf.zoom-x.de/j/6756494866...
Meeting-ID: 675 6494 8662
Kenncode: 929686
All free. Please retweet!

First the science and then the practice! First HyperMet annulliert meeting at the @helmholtzmunich.bsky.social yesterday!

Biological age measured by DNA methylation clocks and frailty: a systematic review and meta-analysis Higher GrimAge EAA is consistently associated with higher frailty. Future research should focus on developing and validating DNA methylation clocks that integrate molecular surrogates of health risk a...

Important article linking methylation clocks to frailty: Biological age measured by DNA methylation clocks and frailty: a systematic review and meta-analysis - The Lancet Healthy Longevity www.thelancet.com/journals/lan...

Troy Hornberger leads research into how hypertrophying muscle generates additional biomass. He is giving the 18th HyperMet talk on the 4th of December from 15-16 h Munich time. The Zoom link is: tum-conf.zoom-x.de/j/6756494866...
Password: 929686

Great to see so many HyperMet members and exercise physiologists with metabolomics data at the DGMet meeting in Hannover. This is a growing field and it is important for us to learn to not only generate data mountains but new ideas that are useful for practice!

Cholsoon Jang is coming as a visiting Professor to Munich for some experimental masterclasses and will give the 19th HyperMet talk next Thursday in person. Join us (details below)!

Pumping Iron Is Their Secret to Aging Well

Pumping Iron Is Their Secret to Aging Well. Not only important for independence & mobility but muscle hypertrophy also has anti-obesity and anti-diabetes effects! www.nytimes.com/2025/07/26/w...

TUM is offering a global postdoc fellowship for talented researchers with a local host. Please e-mail me if you have any questions! Info here: www.tum.de/en/about-tum...

Multi-dimensional metabolomic remodeling under diverse muscle atrophic stimuli in vivo Oyabu et al. establish a metabolomics dataset of muscle-atrophy-associated metabolites (“atrometabolites”) and identify impaired polyamine synthesis as a common feature of various muscle atrophy. The ...

Congratulations to the authors for publishing this paper in on the metabolism of muscle atrophy in Cell Reports! It shows that atrophy is more than just amino acids being released into the circulation.
www.cell.com/cell-reports...

Erik Richter is an exercise physiology legend and will give the 18th HyperMet talk on interaction of exercise and insulin on glucose uptake. tomorrow, Thursday, 28.08.2025 15-16 h Munich time. The Zoom-link is here:
tum-conf.zoom-x.de/j/6920502369...
Password: 702487

One major, unsolved problem is all those unknown signals in MS metabolomics data. To predict what they are, Mike Skinneder has developed DeeMet. He will give the 17th HyperMet talk next Thursday at 15 h Munich time. Join here (please RT): tum-conf.zoom-x.de/j/6392132327...

Really looking forward to Lykke Sylow given the 16th HyperMet talk this Thursday 15 h. Whe will talk about the effect of hypertrophy stimulation on fat mass and glucose homeostasis (recent preprint). Please RT and join here: tum-conf.zoom-x.de/j/6903199711...