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hostmicrobe

@hostmicrobe.bsky.social

Scientist working at the intersection of immunology, microbiology and genomics. Associate Professor and Associate Director of the Institute for Infectious and Zoonotic Diseases at UPenn.

2,302 Followers  |  386 Following  |  12 Posts  |  Joined: 28.08.2023  |  2.0612

Latest posts by hostmicrobe.bsky.social on Bluesky

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Federal Grantmaking Gets a Christofascist Glow-Up Read my zero star review of the new Executive Order

This Executive Order is a gross overreach of Presidential power and undermines democracy. It steals from taxpayers, will destroy science and the economy, and ultimately, America.

Congress must act now.
open.substack.com/pub/rasmusse...

08.08.2025 14:16 β€” πŸ‘ 255    πŸ” 94    πŸ’¬ 7    πŸ“Œ 4

It’s actually even worse: they show it as a gel, which is pure fluorescence units, but a BioAnalyzes records as the molecules pass a single point sensor and critically _fails to normalize for different molecule speeds_

This results in a near-logarithmic overcounting of large molecules!

22.07.2025 02:09 β€” πŸ‘ 30    πŸ” 7    πŸ’¬ 5    πŸ“Œ 0

Unironically they should buy up the domains for about 60 defunct local newspapers in swing states. Hire two reporters to write almost exclusively about highschool sports and new restaurants opening with every 10th article about how the local GOP is screwing over people.

21.05.2025 01:07 β€” πŸ‘ 14258    πŸ” 3883    πŸ’¬ 392    πŸ“Œ 488

The pact of the federal govt with universities was not a handout. It was a strategic decision to boost US leadership in technology, defense, and health. And it paid dividends. In tech, internet, in cancer drugs (for example), No other sector has invested in high risk high reward ideas like US govt.

10.05.2025 02:42 β€” πŸ‘ 419    πŸ” 119    πŸ’¬ 11    πŸ“Œ 3
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An alternative to tSNE & UMAP for more accurate data visualization:

Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data.

The trees are constructed to accurately represent true distances between the objects in the high-dimensional space.

09.05.2025 11:07 β€” πŸ‘ 66    πŸ” 14    πŸ’¬ 3    πŸ“Œ 1
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Research at risk: Life-saving heart pumps for babies | Cornell Chronicle After receiving a stop-work order from the federal government, the future of a device to help children with heart defects is uncertain.

One of grants frozen at Cornell: $6.7M (4 yrs) to develop heart pumps for babies born w/ heart defects.

It took decades of work to get to point of prepping device for in-human clinical trials. No private company could do this.

The cruelty of the Trump administration is heartbreaking. So to speak.

07.05.2025 11:56 β€” πŸ‘ 3405    πŸ” 1790    πŸ’¬ 90    πŸ“Œ 160
Illumina

Due to the #trumptarrifs, Illumina announces that they’ll be adding surcharges all consumables (5%), instruments (2-9%) and services (3.5%). A big hit to labs that are already struggling to do genomics work in an environment with severely reduced federal funding

prdt.illumina.com/webmail/5510...

07.05.2025 01:05 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0
NOT-OD-25-104: Updated NIH Policy on Foreign Subawards NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated NIH Policy on Foreign Subawards NOT-OD-25-104. NIH

This new guidance is yet another step closer towards an isolationist, diminished view of American science. Changing rules on the fly wastes time & effort and undermines the pipeline of discovery and innovation.

Unacceptable & inexcusable (again):

grants.nih.gov/grants/guide...

02.05.2025 01:44 β€” πŸ‘ 53    πŸ” 18    πŸ’¬ 1    πŸ“Œ 3
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Exclusive: NSF stops awarding new grants and funding existing ones US science funder also plans to screen grant applications for compliance with β€˜agency priorities’.

πŸ””BREAKINGπŸ””

The NSF has frozen all research grant awardsβ€”cutting off life-saving science midstream and demanding ideological screenings for future funding.

This is censorship disguised as oversight.

Here’s how you can help us spread the word ➑️🧡(1/3):
www.nature.com/articles/d41...

02.05.2025 01:31 β€” πŸ‘ 603    πŸ” 442    πŸ’¬ 5    πŸ“Œ 29

MS practices DEI for losers.

22.04.2025 00:22 β€” πŸ‘ 10    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

If anyone had proposed this in an NIH application, they would be denied, flagged, barred from further applications, and likely be stripped of research means from their sponsor extramurral institution.

22.04.2025 00:13 β€” πŸ‘ 145    πŸ” 29    πŸ’¬ 5    πŸ“Œ 0

If I see a single school of public health invite this guy to a single panel when this is all over, I swear to god

19.04.2025 19:01 β€” πŸ‘ 76    πŸ” 12    πŸ’¬ 4    πŸ“Œ 0
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'Lab Leak,' a flashy page on the virus' origins, replaces government COVID sites The new page emphatically promotes a theory that many scientists question. Meanwhile, basic information about COVID testing and vaccines has disappeared.

Keep in mind that this is just the beginning. I wouldn't be surprised to see an "official" NIH page saying that vaccines cause autism next. We're far from the bottom.

www.npr.org/sections/sho...

19.04.2025 19:08 β€” πŸ‘ 38    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0

the reposting by CDC kills me

17.04.2025 00:09 β€” πŸ‘ 31    πŸ” 6    πŸ’¬ 3    πŸ“Œ 0
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Biggest commitment to a 3 second joke I've ever seen

09.04.2025 06:33 β€” πŸ‘ 88659    πŸ” 27473    πŸ’¬ 880    πŸ“Œ 1257
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Trump Officials Freeze $1 Billion for Cornell and $790 Million for Northwestern The funding pause amid civil rights investigations into both universities sharply escalates the Trump administration’s campaign against elite colleges.

Trump Officials Freeze $1 Billion for Cornell and $790 Million for Northwestern

The funding pause amid civil rights "investigations" into both universities sharply escalates the Trump administration’s campaign against elite colleges.

08.04.2025 23:34 β€” πŸ‘ 100    πŸ” 57    πŸ’¬ 12    πŸ“Œ 16
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All you need to know about Twitter

23.03.2025 19:07 β€” πŸ‘ 59325    πŸ” 13367    πŸ’¬ 3134    πŸ“Œ 1221
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From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA

22.03.2025 10:44 β€” πŸ‘ 32429    πŸ” 8606    πŸ’¬ 730    πŸ“Œ 298
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Thrilled to team up with @appc.upenn.edu to host Dr. Peter Hotez at Penn this evening for a public lecture on vaccination in a time of rising anti-science rhetoric and policies

19.03.2025 18:49 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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β€œI expect you will eventually find someone who is enough of a fool, or enough of a coward, to file your motion. But it was never going to be me.”

14.02.2025 17:09 β€” πŸ‘ 39955    πŸ” 8727    πŸ’¬ 1062    πŸ“Œ 762

If anyone has the resources to resist, its HHMI. Ending this program with no notice and literally scrubbing evidence it ever existed from the website is shocking and dosappointing

05.02.2025 20:46 β€” πŸ‘ 305    πŸ” 99    πŸ’¬ 16    πŸ“Œ 19

β€œThe recalled product is packaged in two-pound plastic bags with β€˜best if used by’ dates of May 21, 2026, and June 23, 2026. The company and Oregon authorities said that consumers who bought the recalled product should throw it away immediately and contact the place of purchase for a refund.”

26.12.2024 16:49 β€” πŸ‘ 59    πŸ” 49    πŸ’¬ 3    πŸ“Œ 1
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Louisiana forbids public health workers from promoting COVID, flu and mpox shots An NPR investigation found Louisiana health officials told staff to stop promoting vaccines for COVID, flu and mpox, holding flu shot events or otherwise encouraging the public to get those vaccines.

This is outrageous: β€œStaffers were also told that it applies to every aspect of the health department's work: Employees could not send out press releases, give interviews, hold vaccine events, give presentations or create social media posts encouraging the public to get the vaccines.”

20.12.2024 13:16 β€” πŸ‘ 847    πŸ” 411    πŸ’¬ 78    πŸ“Œ 138
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Rwanda’s Marburg response is a masterclass in how to prevent pandemics Today marks the official end of the outbreak. Swift action saved many lives and helped protect the rest of the world from potential disaster

Rwanda’s Marburg response is a masterclass in how to prevent pandemics www.telegraph.co.uk/global-healt...

21.12.2024 11:16 β€” πŸ‘ 88    πŸ” 37    πŸ’¬ 2    πŸ“Œ 2
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Ever wondered how gut microbes control immune responses at extra-intestinal locations?
Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria.
@cellpress.bsky.social ⬇️(1/x)
www.cell.com/cell/fulltex...

19.12.2024 21:30 β€” πŸ‘ 102    πŸ” 39    πŸ’¬ 10    πŸ“Œ 3

I had polio when i was 9. I was taken from my parents & placed in a Hospital for contageous diseases- the polio ward. I would see them once a week - thru the glass window at the end of my ward. I could not walk. It was terrifying. Kids died. Iron lungs were awful. Dont let RFK Jr ban the vaccine

14.12.2024 02:45 β€” πŸ‘ 43611    πŸ” 12339    πŸ’¬ 935    πŸ“Œ 484

Hey #microbiomesky #microsky #IDsky, check out @centermicrobialmed.bsky.social! We are focused on leveraging the microbiome to improve the lives of sick children. We’re also using genomics to track pathogens and reduce infections in kids.

We’re building, growing, hiring, and looking for partners!

13.12.2024 23:46 β€” πŸ‘ 39    πŸ” 13    πŸ’¬ 2    πŸ“Œ 0
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Center for Microbial Medicine Opens to Support Personalized, Microbiome-based Medicine The Center for Microbial Medicine was designated a Center of Emphasis beginning July 1, 2024.

This exciting new Center of Emphasis at CHOP is co-directed by myself, Paul Planet, Bob Baldassano, and @ahmedmicrobes.bsky.social. Reach out with any questions or if you’re interested/excited about this work!

www.research.chop.edu/announcement...

13.12.2024 23:50 β€” πŸ‘ 14    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1
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Research Microbiologist <p>This position is located within the Agricultural Research Service (ARS), Plains Area (PA), at the US Meat Animal Research Center in Clay Center, NE.<br> <br> In this position, you will help to deve...

🚨Job alert🚨. The USDA has posted a Research Microbiologist position in their Meat Safety and Quality Research Unit. Job would focus on Salmonella, E. coli/STEC, AMR, genome sequencing, and the interaction of wildlife and environment with livestock production.

www.usajobs.gov/job/821489600

11.12.2024 13:58 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
PrimalScheme3: primer panels for multiplex PCR primalscheme is a tool for designing primer panels for multiplex PCR. It uses a greedy algorithm to find primers for tiling amplicon generation for multiple reference genomes.

primalscheme3 is now live at primalscheme.com!

Key features
- Handle up to 20% target diversity
- Create panels for multiple targets
- Improved multiplexing, allowing 10x more primer per reaction

Preprint to follow

09.12.2024 14:25 β€” πŸ‘ 17    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0

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