Panagiotis Eleftheriadis

Congratulations to the lab's first PhD student @maxcapelle.bsky.social for defending his PhD last week! Max not only helped shape the lab from day one, but also made outstanding scientific achievements, which have laid the foundation for future research. Wishing him all the best 🥳

Transgenerational Epigenetic Inheritance Please enable JavaScript to proceed.

Transgenerational Epigenetic Inheritance: Twists and turns in the story of learned avoidance

Evidence that learned avoidance of a pathogenic bacterium can be transmitted to future generations in C. elegans is growing.

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CeDNe: A multi-scale computational framework for modeling structure-function relationships in the C. elegans nervous system https://www.biorxiv.org/content/10.1101/2025.11.03.683805v1

Zebrafish use spectral information to suppress the visual background Vertebrate eyes first evolved in water, where spectral content rapidly fades with distance. Zebrafish exploit this loss by antagonizing cone signals to suppress the background, pointing to distance es...

Excited to share our paper now published in Cell!
'Zebrafish use spectral information to suppress the visual background'

Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social

@cellpress.bsky.social @cp-cell.bsky.social

👇🏻
www.cell.com/cell/fulltex...

sure, if you enjoy the horrifying limits of human perception

Behavioral and circuit principles of temperature gradient navigation Behavioral thermoregulation is critical for survival across animals. Balakrishnan and Haesemeyer discover that thermoregulatory behavior in larval zebrafish is organized into longer-term swim modes. T...

Out now in @currentbiology.bsky.social led by Kaarthik A Balakrishnan: We identify medullary circuits that represent the valence of thermal stimuli and control both long-term strategies of cold-avoidance and short term hot avoidance behaviors to enable thermoregulation. www.cell.com/current-biol...

Understanding consciousness as a fractal What if you are a pixel in a higher-level consciousness navigating through extra dimensions of time? Meet the 'Nested Observer Window Model' of Jonathan Schooler, PhD, who is Distinguished Professor o...

What if you are a pixel in a higher-level consciousness navigating through extra dimensions of time? Meet the ‘Nested Observer Window Model’ of Jonathan Schooler, PhD, Distinguished Professor of Psychological and Brain Sciences UCSB.
www.essentiafoundation.org/12750-2/seei...

one of the cool things about rock climbing as a hobby is that you gradually lose the ability to be recognized by fingerprint scanners

A multisensory, bidirectional, valence encoder guides behavioral decisions A key function of the brain is to categorize sensory cues as repulsive or attractive and respond accordingly. While we have some understanding of how sensory information is processed in the sensory pe...

How is valence computed in the brain? Check out our new preprint about a single cell that integrates excitatory and inhibitory input across modalities according to valence and impacts behavioral decisions. An exciting collaboration across many labs. Enjoy reading!
www.biorxiv.org/content/10.1...

a black and white dog is sitting on a couch with its tongue sticking out . ALT: a black and white dog is sitting on a couch with its tongue sticking out .

👁️The retina — strikingly conserved across vertebrates, but an oddity among bilaterians!

So how did it evolve?

With @mikebok.bsky.social, @neurofishh.bsky.social and @denilsson.bsky.social, we argue that retinal complexity may 𝑝𝑟𝑒𝑑𝑎𝑡𝑒 𝑡ℎ𝑒 𝑒𝑦𝑒 𝑖𝑡𝑠𝑒𝑙𝑓.

www.biorxiv.org/content/10.1...
1/n

Congratulations to Anna Stöckl receiving the prestigious Walther-Arndt award from the German Zoological Society. #dzg2025 @anna-stoeckl.bsky.social 🥳🥂

Multiplexing behavioral signals in sensory representations https://www.biorxiv.org/content/10.1101/2025.09.04.674251v1

Amazing work on bee photoreceptors by my good friend @gkolyfetis.bsky.social!

How do brains make decisions when faced with multiple, potentially conflicting cues? In our latest preprint, we show how #zebrafish use an additive strategy and process multiple visual features through anatomically distinct parallel pathways tinyurl.com/mvkn8em9 Thread 👇

It’s surreal to think that every neuron and synapse in the fly brain + cord that was dissected almost five years ago (the photo’s still on the lab slack!) is now just a click away on Codex codex.flywire.ai?dataset=banc. This wouldn’t have been possible without the incredible team behind it!

Hillel Adesnik lecturing in the MBL Visual Neuroscience course. Clear as a bell, as usual.

Some zebrafish line eye dancing at @mblscience.bsky.social Visual Neuro course. Teaching OKR how John Dowling and Jim Fadool taught me during the zebrafish course.

And today: Dave Zenisek and more ribbons!
@mblscience.bsky.social Visual Neuro course

Day 1 of the Visual Neuroscience course at the MBL in Woods Hole. The legendary John Dowling and Michael Do, both from Harvard, gave fabulous intro lectures on photoreceptors And the lab is humming! Can’t wait for day 2!

The Behavioural Neurobiology Summer School in Kosovo is back for the 2nd year and after just a few days we already made it onto live TV! For anyone who speaks Albanian, you can check out the full broadcast here: shorturl.at/kpUzp 🎙️

Seeing the world through the lens of oscillations - we are delighted to share our new paper where we demonstrate that anatomically resolved oscillatory bursts reveal dynamic motifs of thalamocortical activity during naturalistic stimulus viewing (doi.org/10.1016/j.ne...).

Check out this amazing work by my friend and colleague @maxcapelle.bsky.social !!

Memory by a thousand rules: Automated discovery of functional multi-type plasticity rules reveals variety & degeneracy at the heart of learning Synaptic plasticity is the basis of learning and memory, but the link between synaptic changes and neural function remains elusive. Here, we used automated search algorithms to obtain thousands of str...

We just pushed “Memory by a 1000 rules” onto bioRxiv, where we use clever #ML to find #plasticity quadruplets (EE, EI, IE, II) that learn basic stability in spiking nets. Why is it cool? We find 1000s!! of solutions, and they don’t just stabilise. They #memorise! www.biorxiv.org/content/10.1...

From Morphology to Computation: How Synaptic Organization Shapes Place Fields in CA1 Pyramidal Neurons The synaptic mechanisms driving feature selectivity in specific neuron types remains a fundamental and unresolved challenge in neuroscience. In hippocampal CA1 pyramidal neurons (PNs), the development...

New collaborative preprint with Losonczy Lab and Polleux Lab!
How does synaptic organization shape place fields in CA1 Pyramidal Neurons?
We mapped thousands of synapses & showed that clustering of excitatory inputs is key for tuning.
www.biorxiv.org/content/10.1...
#Neuroscience #bioRxiv

Housing and husbandry factors affecting zebrafish novel tank test responses: a global multi-laboratory study Lab Animal - This Article presents the results of a global multi-laboratory study assessing the effects of housing conditions and experimental settings on novel tank test responses in adult zebrafish.

Just out in Lab Animal: our new global multi-lab zebrafish study is live! Housing and husbandry variables can significantly alter zebrafish anxiety-like behaviour. This is a call for better reporting and #standardisation in #zebrafish research. @uniofsurrey.bsky.social

Open access: rdcu.be/enHLj

Horizontal cell connectivity in the anchovy retina—a 3D electron microscopic study - BMC Biology Background Block-face scanning electron microscopy has opened a new era of connectomics research, in which it is possible to make dense reconstructions of all cells in a clipping of a neuronal network...

I am excited to share our new paper on anchovy retina connectomics! This was a great collaboration with Prof. Heß at LMU Munich and an incredible opportunity to explore neural circuitry in a unique visual system.
bmcbiol.biomedcentral.com/articles/10....

I'm really happy to share the first preprint of my PhD work in @jjfosterlab.bsky.social! During a fruitful collaboration with @gregoeur.bsky.social, we uncovered a surprising feature of bees' eyes!
www.biorxiv.org/content/10.1...

Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish Accumulating information is a critical component of most circuit computations in the brain across species, yet its precise implementation at the synaptic level remains poorly understood. Dissecting su...

We are proud to present our new preprint “Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish”, just posted on bioRxiv (www.biorxiv.org/content/10.1...). (1/10)

Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish https://www.biorxiv.org/content/10.1101/2025.03.14.643363v1

Peptidergic modulation of motor neuron output via CART signaling at C bouton synapses | PNAS The intensity of muscle contraction, and therefore movement vigor, needs to be adaptable to enable complex motor behaviors. This can be achieved by...

Also pinned here! Our paper that reveals the CART peptide as a novel modulator of motor output in demanding tasks! @pnas.org

www.pnas.org/doi/abs/10.1...