Alltrna

If you’re at #JPMWeek, check out Wednesday’s live recording of The Genetics Podcast for a conversation on translating emerging RNA and gene-editing modalities into meaningful patient benefit, featuring Alltrna CEO @mcw44.bsky.social.

bit.ly/3YxH8w5

#tRNA #StopCodonDisease #RNAsky #JPM26

2025 was a year of momentum and big leaps at Alltrna. Each step reflected our belief that patients deserve better and our commitment to boldly building a new future for those with Stop Codon Disease. We look forward to 2026 and taking the next meaningful leaps in the clinic.

As the year wraps up, we’re grateful for our Alltrna team and the way they showed up for one another and our community. From our String of Giving donation drive to a little holiday fun together, thank you for an incredible year. Warm holiday wishes from all of us at Alltrna.

From patents to patients. For Nick Triano, protecting innovation in biotech also means making an impact in #raredisease treatment. Meet Alltrna's Senior Legal Counsel in the latest #EmployeeSpotlight posted on www.alltrna.com/life-at-allt....

#WeAreAlltrna

Today is #PKUAwarenessDay. Additional #genetictesting can help people with #PKU understand the variants (aka mutations) behind their disease which can guide care and clarify eligibility for #clinicaltrials.

Watch the video from #NPKUA and @nordrare.bsky.social to learn more: bit.ly/48psGe0

This November, we set aside time to reflect, say thank you, and celebrate our team. #Gratitude is not limited to one month for us. It is part of who we are as one team and how we give our best to build a new future for patients every day.

#WeAreAlltrna

At the 2nd MENA Congress for Metabolism in Health and Disease 2025, Alltrna highlighted how engineered #tRNA medicines can restore protein synthesis in liver #StopCodonDisease and inborn errors of metabolism.

metabolism.ae

#RNAsky

Small groups, big impact. Our new Peer Mentoring Circles give colleagues space to share experiences, build skills, and strengthen community. The first session was a success! We’re excited to see how far we go and grow together.

#WeAreAlltrna #Mentorship #LifeAtAlltrna

Alltrna CMO Dr. Nerissa Kreher will join leaders from across the #raredisease field for a panel titled, “𝘼 𝙉𝙚𝙬 𝙀𝙧𝙖 𝙛𝙤𝙧 𝙍𝙖𝙧𝙚 𝘿𝙞𝙨𝙚𝙖𝙨𝙚 𝘾𝙡𝙞𝙣𝙞𝙘𝙖𝙡 𝙏𝙧𝙞𝙖𝙡𝙨,” at the 𝗡𝗢𝗥𝗗 𝗥𝗮𝗿𝗲 𝗗𝗶𝘀𝗲𝗮𝘀𝗲𝘀 & 𝗢𝗿𝗽𝗵𝗮𝗻 𝗣𝗿𝗼𝗱𝘂𝗰𝘁𝘀 𝗕𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗦𝘂𝗺𝗺𝗶𝘁 in Washington, D.C.

#NORDSummit: nordsummit.org

@nordrare.bsky.social

Behind every breakthrough at Alltrna are people who are not only scientists, innovators, and colleagues, but also parents and caregivers. For Working Parent Awareness Day, our Culture Team hosted an excellent panel about balancing family life with meaningful work.

#NationalWorkingParentsDay

95% of genetic #rarediseases lack therapies. On #InternationalPodcastDay, Alltrna CEO @mcw44.bsky.social shares how engineered #tRNA medicines can restore protein production and uniquely treat many diseases with the same underlying mutation.

bit.ly/3VR6LXd

#RNAsky #StopCodonDisease

Congrats to our colleagues at Flagship Pioneering on 25 years of turning bold ideas into medicines. At Alltrna, we’re building on this legacy of #BiggerLeaps by pioneering #tRNA medicines to unify treatment across #StopCodonDisease and redefine what’s possible for patients.

#FlagshipFounded

For Ayush, science is both an intellectual challenge and a creative pursuit. He has turned his passion into possibility in his role as a research associate at Alltrna, where he explores massive design spaces to find the best tRNAs for therapeutic development.

www.alltrna.com/life-at-allt...

New tRNA tech aims to rewrite rare disease treatment Explore the role of tRNA in genetic medicine and how Alltrna is revolutionizing therapies for rare genetic diseases.

Drug Target Review spotlights Alltrna’s mutation-driven strategy to expand the reach of genetic medicine. By focusing on the shared genetic cause, rather than one disease at a time, our tRNA therapeutic approach can accelerate rare disease drug development.

bit.ly/4858rUi

#StopCodonDisease

Alltrna appoints Dave Hava as CSO. With two decades translating breakthrough science into first-in-class drugs, he will expand and prioritize our tRNA medicines pipeline. Grateful to our first CSO Chris Henderson, who will continue to guide our science as our SAB chair.

bit.ly/4mPxcbK

An image with Nerissa and details of Alltrna's presentation at ICIEM 2025

We’re pleased to share that Alltrna will present at the International Congress of Inborn Errors of Metabolism (ICIEM 2025), taking place September 2-6 in Kyoto, Japan.

For more info: site2.convention.co.jp/iciem2025/we...

#ICIEM2025 #RNAsky #StopCodonDisease #rarediseases #tRNA

Alltrna volunteers spent our annual #DayofService with Cradles to Crayons, helping provide essential items to children living in low-income and homeless situations.

Proud to support their mission to #EndClothingInsecurity, www.cradlestocrayons.org.

#WeAreAlltrna

For #RNADay, we’re spotlighting the therapeutic potential of #tRNA to move beyond the one-gene, one-disease, one-drug paradigm and scale genetic medicine for thousands of rare diseases.

Learn more: www.alltrna.com/trna-biology

#RNAsky #WorldRNADay

Image: Disability Pride Flag Use: Symbol of the Disability community and the Disability Pride Movement Description: A charcoal grey flag bisected diagonally from the top left corner to the lower right corner by five parallel stripes in red, pale gold, pale grey, light blue, and green. Designed to be visually safe and inclusive. Designed by Ann Magill and adopted into use in 2021.

July is #DisabilityPrideMonth, reminding us that disability is a natural and valuable part of human diversity. At Alltrna, accessibility is not a project – it is woven into our values. We are one team, embracing all voices and experiences as we advance tRNA therapeutics for patients.

#WeAreAlltrna

Earlier this month we took a moment collectively to recharge, so we could return to work with fresh perspectives. At Alltrna, curiosity sparks discovery, and time away helps us thrive. When we reunite, we’re one team, committed to giving it our all for patients everywhere.

#WeAreAlltrna

Ancient Molecule, Modern Medicine: The Science, Strategy, & Stakeholders Behind tRNA Therapeutics <p>As we all know well, &ldquo;unearthing&rdquo; our molecules&rsquo; potential poses numerous technical and business-related challenges for young biotech companies. Here, Werner and I continue our conversation, unpacking some of these internal and external challenges the company is navigating as it strives to bring tRNA to the commercial market.</p>

Raiders of the Lost Codon Part 2: The Hunt Continues.

In this new Advancing RNA article, Alltrna CEO @mcw44.bsky.social 4.bsky.social shares how we’re navigating the scientific and strategic challenges of bringing our first #tRNA medicines to patients.

bit.ly/451yuc7

#StopCodonDisease #RNAsky

At the Propionic Acidemia Conference, we presented about how premature stop codons cause #rarediseases, like PA, and the need for #genetictesting, even after a diagnosis.

If you missed it, you can learn more about #tRNA therapeutics and #StopCodonDisease here: www.alltrna.com/stop-codon-d....

For #PrideMonth2025, Alltrna is reading and discussing The House in the Cerulean Sea by TJ Klune. It’s a beautiful story about identity and belonging. We also gathered for a Pride happy hour to connect and reflect on what inclusion and belonging mean to each of us.

#WeAreAlltrna #PrideMonth

Joyner Eke’s job is about more than engineering a molecule – it’s about building a future where more families have more time. Her work in process development and purification is critical to scaling Alltrna’s #tRNA medicines.

Watch her video here: www.alltrna.com/life-at-allt...

#StopCodonDisease

Alltrna scientists presented at #RNA25 and the 2025 IRSF #RettSyndrome Scientific Meeting on our advancement of #tRNA as a new therapeutic modality to treat diseases caused by the same underlying mutation.

Thanks to our team for their outstanding work!

#StopCodonDisease #RNAsky

Thank you for an incredible discussion on next-gen advocacy in rare disease at #BIO2025. Real change takes all of us – patients, families, regulators, industry – pushing forward together.

#RNAsky #rarediseases

Don't forget -- our panel is today at 1:45pm ET in Room 251!

#BIO2025

On Behind the Breakthroughs #podcast, Alltrna CEO @mcw44.bsky.social shares how personal experience drives our mission – and how engineered tRNAs could unlock new treatments for diseases caused by premature stop codons.

Read the Q&A & listen here: bit.ly/4mZWjZN

#tRNA #StopCodonDisease #RNAsky

Congratulations to Sandra Visser, Ph.D., SVP, Head of Therapeutics Development at Alltrna, on being named President of @ascptclinpharm.bsky.social for 2025-2026! We’re proud to see her leadership recognized by the clinical pharmacology community.

#ASCPT2025 #PatientCentricity

Bright breakthroughs: Real stories of beating rare disease

When @mcw44.bsky.social's son was diagnosed with #Duchenne, patient groups became a lifeline. In this @science.org webinar, she shares how that shaped her leadership at Alltrna, listening to families as we develop #tRNA medicines to treat #StopCodonDisease.

www.science.org/content/webi...

#RNAsky