It's really real πππ Huge thanks to Wrapper's Delight ( @wrapplab.bsky.social ) and T-Pain ( @timothysheahan.bsky.social ) for everything. Working on this together was the best part of 2025!
10.01.2026 14:42 β π 7 π 4 π¬ 1 π 0@wrapplab.bsky.social
Host-pathogen interactions, structural biology, protein design and more. Assistant Professor at Duke University. www.wrapplab.org
It's really real πππ Huge thanks to Wrapper's Delight ( @wrapplab.bsky.social ) and T-Pain ( @timothysheahan.bsky.social ) for everything. Working on this together was the best part of 2025!
10.01.2026 14:42 β π 7 π 4 π¬ 1 π 0Human coronavirus 229E antibodies and Spike structure function paper is finally out for real. Led by @wrapplab.bsky.social (wrappers delight) and @mlicc1701.bsky.social (MFL) #lovevirology #229E #antibodies www.nature.com/articles/s42...
10.01.2026 13:06 β π 10 π 3 π¬ 1 π 1A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain
www.nature.com/articles/s42...
@wrapplab.bsky.social
Excited to share a new publication from my PhD labs where we explore a method to improve antibody-mediated protection against herpes simplex virus infections: www.science.org/doi/10.1126/...
19.11.2025 19:04 β π 6 π 3 π¬ 0 π 0I'm honored to receive a MacArthur Fellowship. As always, I extend my sincerest thanks to all my wonderful mentors, colleagues, collaborators, admins, and trainees who make this work possible. #MacFellow
08.10.2025 19:59 β π 222 π 34 π¬ 32 π 2As part of our 2025 βRising Stars in #Vaccinology and #Immunity to #Microbesβ seminar series, we spoke with Dr. Daniel Wrapp @wrapplab.bsky.social who uses structure-based design to develop new #antiviral therapies. cvimp.podbean.com/e/episode-13...
02.09.2025 02:13 β π 16 π 7 π¬ 0 π 0Our latest preprint is now available doi.org/10.1101/2025...! Led by my postdoc, Luqiang Guo @luqiang.bsky.social, we determined a ~2.4 A resolution structure of the hantavirus glycoprotein tetramer on the surface of VLPs. Also determined structures of dimers of tetramers and Fab-bound tetramers.
18.06.2025 14:24 β π 69 π 23 π¬ 2 π 2Design, Structure, and Immunogenicity of a Soluble Prefusion-stabilized EBV gB Antigen www.biorxiv.org/content/10.1101/2025.05.19.654955v1 #cryoEM
20.05.2025 07:10 β π 5 π 5 π¬ 0 π 0Very excited to share our latest preprint describing the isolation and characterization of neutralizing HCoV-229E-directed antibodies from a human donor! Great collaboration between DHVI and the Baric and Sheahan (@timothysheahan.bsky.social) labs at UNC.
www.biorxiv.org/content/10.1...