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Daniel Wrapp

@wrapplab.bsky.social

Host-pathogen interactions, structural biology, protein design and more. Assistant Professor at Duke University. www.wrapplab.org

254 Followers  |  57 Following  |  1 Posts  |  Joined: 12.11.2024  |  1.632

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Our latest preprint is now available doi.org/10.1101/2025...! Led by my postdoc, Luqiang Guo @luqiang.bsky.social, we determined a ~2.4 A resolution structure of the hantavirus glycoprotein tetramer on the surface of VLPs. Also determined structures of dimers of tetramers and Fab-bound tetramers.

18.06.2025 14:24 β€” πŸ‘ 62    πŸ” 21    πŸ’¬ 2    πŸ“Œ 2

Design, Structure, and Immunogenicity of a Soluble Prefusion-stabilized EBV gB Antigen www.biorxiv.org/content/10.1101/2025.05.19.654955v1 #cryoEM

20.05.2025 07:10 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain HCoV-229E is an endemic Alphacoronavirus that typically causes common cold-like disease in most healthy adults, but can also cause severe respiratory disease in the very young and the elderly. Althoug...

Very excited to share our latest preprint describing the isolation and characterization of neutralizing HCoV-229E-directed antibodies from a human donor! Great collaboration between DHVI and the Baric and Sheahan (@timothysheahan.bsky.social) labs at UNC.

www.biorxiv.org/content/10.1...

19.05.2025 10:34 β€” πŸ‘ 17    πŸ” 11    πŸ’¬ 1    πŸ“Œ 2

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