marius walter

A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging Efficient DNA repair might make possible the longevity of naked mole-rats. However, whether they have distinctive mechanisms to optimize functions of DNA repair suppressors is unclear. We find that naked mole-rat cyclic guanosine monophosphate–adenosine ...

A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging

Naked mole rats get much older than closely related mamals of a similar size. cGAS mutations may have an important role in this.

www.science.org/doi/...
1/9

That it loops back has never been tested tho..

I love E2F6

hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

Very interesting!

Haha he was my number 2. I’m probably missing context about the original post

I barely post so you’re not missing much!

Who’s the 3rd one tho?

This is the norm in many countries, but I think it’s a shame to lose it. I always thought it was one of the great feature of US PhD programs

🥳 Very grateful for the support of the ERC Starting Grant for my newly established lab! We will study how transposable elements contribute to mammalian embryonic development.
We will have positions available next year. Stay tuned!

This is insane

In France 90% of the milk is UHT for some reason, and I think it’s pretty high in other European countries too

Mortality Rates, Mortality Rate Ratios, and Excess US Deaths Attributable to the US Mortality Disadvantage Relative to Other High-Income Countries (HICs)

Super interesting deep dive into US excess mortality. We're doing better than we were in 1980 but a *lot* worse than every other high-income country.
jamanetwork.com/journals/jam...

It’s only Monday tho

It may be too slow

There is a also a c in blueberry. Or maybe not.

You must never have tried good butter

The cover of Nature Genetics July 2025 issue. Digital art of a mouse paw skeletal prep on dark background, digits I to IV disintegrating into viral particles. A caption says “An endogenous retrovirus causes limb malformation”.

Pretty surreal to see my artwork on the cover of Nature Genetics! Big congrats to @julianeg.bsky.social, @stemundi.bsky.social and the others, and thank you Juliane for letting me help bring your research to life visually.

www.nature.com/ng/volumes/5...

The payline in this context is the proportion of grant proposals that are funded by NCI. So we’re going from 10% to 4% of proposals receiving money

it was before I knew @rqperezpalacios.bsky.social, but I think it’s a tie

Even as a staff scientist I get asked to review maybe once or twice a year

For sure

I would be happy to try both 😅

Of all the social media content of the last 24h, THIS is the most wrong 😑

⚠️ Discovery of a new mode of viral transmission:

Deltaviruses spread through a viral Trojan Horse !

These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!

www.biorxiv.org/content/10.1...

A thread 1/14

I don’t think this is Bluesky’s fault or that anything changed tho. It’s just that American users are in deep trauma and that sets the tone

There will be, maybe, for the lucky few, but the math do not work at scale.
And wait until you find out how much you would get paid in a lot of other countries…

Whatever trickery this is, this is wrong 😑

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs.

Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design

Please repost for reach 💚

The French mind cannot comprehend