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jacobboysen.bsky.social

@jacobboysen.bsky.social

The liminal space between self and non-self. AI x genome grammars. Noncoding, TEs, UTRs, that sort of thing.

85 Followers  |  334 Following  |  7 Posts  |  Joined: 16.01.2024  |  1.5291

Latest posts by jacobboysen.bsky.social on Bluesky

Autosomes, not autonomies lol

12.03.2025 06:06 — 👍 0    🔁 0    💬 0    📌 0

Is it common to have these y-chromosome-like fixed non-recombining regions across plant autonomies? Plants you crazy bastards….

12.03.2025 06:05 — 👍 0    🔁 0    💬 1    📌 0

Plants are nuts, your work is really cool. I haven’t spent a lot of time with your papers so apologies for ignorance, but just perusing, it looks like 3’UTR repeats are a dominant theme? And evidence for small RNAs or possibly (I assume) some other trans factor being the limiting timing factor?

12.03.2025 06:04 — 👍 1    🔁 0    💬 2    📌 0

I love the idea anchor species but I wonder if they need to be tied phylogenetically or if they need to based off genome architecture characteristics. Yeast and fission yeast and candida for example, very different genome architectures due to ecology and domestication etc

06.03.2025 01:19 — 👍 1    🔁 0    💬 0    📌 0

Right right, so this matches my mental model as well. We’re trying to brute force speak genome Esperanto when we barely speak a few genome languages “well”. Compared to proteins where the language is the same across all species essentially

06.03.2025 01:16 — 👍 1    🔁 0    💬 1    📌 0

What do you mean by better labels and tricks? Much higher quality annotation of ref genomes?

06.03.2025 00:23 — 👍 0    🔁 0    💬 1    📌 0

Are these SINE fossils? Ie do they have limited seq complementarity? You can….go down a really big rabbit hole here

12.12.2024 16:34 — 👍 2    🔁 0    💬 0    📌 0

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