Armin Toghi

Non-invasive ultrasonic neuromodulation of the human nucleus accumbens impacts reward sensitivity - Nature Communications This study shows that non-invasive ultrasound to the human nucleus accumbens can modulate deep brain activity and enhance reward-guided learning, offering a potential alternative to invasive neuromodu...

New study out today in Nature Comms: www.nature.com/articles/s41..., in which we set out to test whether ultrasound could influence the reward-related learning computations of the nucleus accumbens, building on decades of work on dopaminergic prediction error and reinforcement learning. And it did.

Transdiagnostic eye-tracking biomarkers of inattention across psychiatric disorders: a systematic review - BMC Psychiatry Attention impairment is a dimensional and heterogeneous trait, distributed continuously across the population. Understanding the pathophysiology of eye movement control offers valuable insight into at...

Happy to share our new publication in BMC Psychiatry. @bmc.springernature.com

bmcpsychiatry.biomedcentral.com/articles/10....

🗯️ Here, we aimed to map different oculomotor paradigms metrics to key attention systems across psychiatric conditions, including ADHD, ASD, TS, OCD, BPD, DCD, and SSD.

😳😳🫣

The findings highlighted impairments in several key oculomotor metrics shared across psychiatric conditions, and moderately correlated with self-reported and behavioral measures of inattention symptoms. 3/

Attention impairment is a dimensional and heterogeneous trait, distributed continuously across the population.

Understanding the pathophysiology of eye movement control offers valuable insight into attention dysfunctions and their underlying neural circuits. 2/

Transdiagnostic eye-tracking biomarkers of inattention across psychiatric disorders: a systematic review - BMC Psychiatry Attention impairment is a dimensional and heterogeneous trait, distributed continuously across the population. Understanding the pathophysiology of eye movement control offers valuable insight into at...

Happy to share our new publication in BMC Psychiatry. @bmc.springernature.com

bmcpsychiatry.biomedcentral.com/articles/10....

🗯️ Here, we aimed to map different oculomotor paradigms metrics to key attention systems across psychiatric conditions, including ADHD, ASD, TS, OCD, BPD, DCD, and SSD.

Contents of visual predictions oscillate at alpha frequencies Predictions of future events have a major impact on how we process sensory signals. However, it remains unclear how the brain keeps predictions online in anticipation of future inputs. Here, we combin...

@dotproduct.bsky.social's first first author paper is finally out in @sfnjournals.bsky.social! Her findings show that content-specific predictions fluctuate with alpha frequencies, suggesting a more specific role for alpha oscillations than we may have thought. With @jhaarsma.bsky.social. 🧠🟦 🧠🤖

Confronting the connectivity crisis in human M/EEG research The cognitive neuroscience community using M/EEG has not converged on measures of task-related inter-regional brain connectivity that generalize across tasks and laboratories. We call for community-driven efforts to systematically test and validate connectivity metrics using shared datasets and protocols, aiming to establish robust, replicable frameworks for cognitive and clinical applications.

Online Now: Confronting the connectivity crisis in human M/EEG research

Hierarchical neurobiological changes in dorsolateral prefrontal cortex and subgenual anterior cingulate cortex connectivity induced by theta-burst stimulation Recent studies show that left dorsolateral prefrontal cortex (DLPFC) stimulation induces acute and persistent changes in the subgenual anterior cingulate cortex (sgACC), and the degree of sgACC modula...

Preprint Alert🧑‍💻

In our new study we track hierarchical neurobiological changes 2, 15, 30 minutes post TBS protocols (cTBS, iTBS, Sham) using spDCM under conductance based canonical microcircuit neural mass model🧠📝.

www.medrxiv.org/content/10.1...

For TMS studies to be reproducible and for us to build on each other’s findings, we need to report what we actually did during the experiment.

We've built and now are evaluating the TMS-RAT (Reporting Assessment Tool).

Check out our website! - built by @thehandlab.bsky.social

Researchers reveal how our brains predict what we’re about to see Researchers in the UCL Queen Square Institute of Neurology find that the hippocampus sends signals to the visual cortex to predict what we are about to see.

News story on the UCL Brain Sciences website about our recent paper using 7T fMRI to study the communication between hippocampus and neocortex. www.ucl.ac.uk/brain-scienc... Link to the paper: www.science.org/doi/10.1126/.... #neuroskyence

Any comments would be useful for improving the work!!

feel free to criticize 🙂

Using a multilevel parametric empirical Bayes framework, we observed that
1. cTBS induce wider network effect 2 min after stimulation while iTBS made more lasting changes up to 30 min.
2. TBS caused sustained inhibition within left sgACC microcircuits by increased ss inhibition.

Our study builds on recent findings highlighting the remote modulatory effects of
rTMS over the DLPFC on the sgACC, and its relevance to antidepressant outcomes. Here we used a cutting-edge, biophysically informed neural mass model on bilateral DLPFC-sgACC connectivity.

Hierarchical neurobiological changes in dorsolateral prefrontal cortex and subgenual anterior cingulate cortex connectivity induced by theta-burst stimulation Recent studies show that left dorsolateral prefrontal cortex (DLPFC) stimulation induces acute and persistent changes in the subgenual anterior cingulate cortex (sgACC), and the degree of sgACC modula...

Preprint Alert🧑‍💻

In our new study we track hierarchical neurobiological changes 2, 15, 30 minutes post TBS protocols (cTBS, iTBS, Sham) using spDCM under conductance based canonical microcircuit neural mass model🧠📝.

www.medrxiv.org/content/10.1...

Happy to share a new perspective on Loneliness and social conformity: A predictive processing perspective led by Naem Haihambo & Dirk Scheele & his team @ruhr-uni-bochum.de nyaspubs.onlinelibrary.wiley.com/doi/epdf/10....

A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.

It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠

🧵 How do psychedelics shape brain activity?

Our new paper presents the largest neuroimaging study of psilocybin to date—revealing how context structures psychedelic brain states.

Title: Psychedelics Align Brain Activity with Context
Paper: lnkd.in/gt-kMR6d

A thread 🧵👇 1/n

UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

We have an opening for a 12 month Research Assistant post, funded by an ERC grant. The postholder would help with several neuroimaging projects, including MEG and 7T fMRI. Please repost and share with anyone who may be interested. www.ucl.ac.uk/work-at-ucl/... #neuroskyence #Neuroimaging

Predictive coding folks!
Found sth new for your presentations😂

Great. What is the closest atlas and network available that cover most of the AMN regions?

Schemas, reinforcement learning and the medial prefrontal cortex - Nature Reviews Neuroscience A computational account of how schemas are learned through experience is lacking. In this Perspective, Bein and Niv synthesize schema theory and reinforcement learning research to derive computational...

Excited to share this perspective with @yaelniv.bsky.social about how schemas might be learned and instantiated via reinforcement learning, latent cause inference, and dimensionality reduction, and what's the medial prefrontal cortex might be doing for all of these www.nature.com/articles/s41...

Spanning spatial scales with functional imaging in the human brain; initial experiences at 10.5 Tesla https://www.biorxiv.org/content/10.1101/2024.12.20.629800v1

Is it an obvious human bias that we think we were lucky, while we really didn't experience the other option(s)?

Fresh out: a short review article where I give an overview of different ways that across-trial temporal structure is helpful in understanding cognitive models of decision-making

osf.io/preprints/ps...

📣 #PhD position announcement📣 (please share)

We're seeking applicants for a joint venture with University of St. Andrews (lead by Thomas Otto) exploring how we can optimise measures of #multisensory #perception for remote data collection.

Find out more here👇

https://buff.ly/3ZJk131

A causal role of the right dorsolateral prefrontal cortex in random exploration - Scientific Reports Scientific Reports - A causal role of the right dorsolateral prefrontal cortex in random exploration

Check out our work recently published in Scientific Reports 🧠🧑‍💻

www.nature.com/articles/s41...

Our study explored role of right DLPFC in different explorative strategies, using TMS and Horizon Task.

What is the point of predicting neuroscience results based on abs or intro in our everyday tasks? I'm still not getting the point!!

My paper is out!! 🎉

"Opponent control of reinforcement by striatal dopamine and serotonin", @Nature

Here, we show that dopamine and serotonin signals form a gas-brake system for reward in the mammalian brain

THREAD ⬇️

1/n

Heard that. I should try this. Thanks🙏