Andre Rendeiro

Images of cells showing protein mislocalization caused by a Noonan syndrome mutation, with the idea to screen drugs to find any that can reverse the unhealthy mislocalization

Have $10M and want to cure some diseases?

It costs ~$1B to invent a new medicine…but $10M buys you Project Encore, to see if ANY existing drug might be repurposed for ~100 diseases that have no treatments.

Contact me - be a hero for desperate patients!
docs.google.com/document/d/1...

Data Scientist / Software Engineer in Computational Biology (f/m/d) - Vienna (Landbezirke) (AT) job with Research Center for Molecular Medicine (CeMM), ÖAW | 12842231 The Rendeiro lab at CeMM is recruiting a highly motivated data scientist to join our international team studying human aging and pathology.

🚨 We're hiring! The Rendeiro Lab @cemm.oeaw.ac.at is looking for a data scientist or software engineer to work on open-source tools for spatial, histological & multimodal data.
Ad: www.nature.com/naturecareer...
More info: rendeiro.group

Well deserved, congratulations!

Join two powerhouses of research driving innovation in artificial intelligence and biomedicine in Vienna!

My group will be recruiting a PhD student to continue and extend our work on spatially resolved study of aging via principled computational approaches:
rendeiro.group
apply.cemm.at

the treasure trove of all sequencing datasets

Excited to share a new preprint from the lab with @ryandhindsa.bsky.social ! www.biorxiv.org/content/10.1...

Led by @sherrynyeo.bsky.social, @erinmayc.bsky.social, and friends, we continue our journey to find viral DNA in our favorite place-- the overlooked and discarded reads in existing data! 1/

Die Blutbaustelle − Helfer im Einsatz! - KinderuniOnline Ein blutendes Knie? Kein Problem, denn in deinem Körper startet sofort der Superhelden-Einsatz! Im kurzen Video „Die Blutbaustelle – Helfer im Einsatz!“ zeigen wir dir, wie Plätti und die weißen…

⭐ CeMM is proud to have supported #KinderuniWien together with @oeaw.bsky.social again this year!
We created a fun online video, quiz & game to show children how wounds heal & the immune system protects us. Watch it below 👇

🎥 “Die Blutbaustelle - Helfer im Einsatz!” (in German)
🔗

Thanks! Could you please add me?

I received some old microscopy slides from the 1800s, when at-home microscopes made it possible to look at hidden worlds of diatoms, polycystina, and other teeny tiny things.

I made this website so people today can take a look too: microspeci.men

Enjoy! #scienceisforeveryone #microscopy #HistSci

LazySlide 🦥 just hit 100 GitHub stars! 🎉 Our free, open-source framework is making whole slide analysis easier than ever. Built on scverse 🐍, it handles everything from tissue segmentation to multi-omics workflows 🤹 & deep learning 🏋️. Big thanks to the community!
www.biorxiv.org/content/10.1...

Absolutely, hard to overstate

📢 Announcing the MOPITAS Autumn School on Spatial Transcriptomics Data Analysis – taking place November 12–14, in Munich. Don't miss this excellent opportunity to deepen your expertise in data science and multi-OMICS analysis - especially as a PhD student in the data science community.

How Should Portuguese Americans Be Classified? The question of who Portuguese Americans are—white, Hispanic, minority, nonminority—remains unsettled.

This was interesting: How should Portuguese Americans be classified? www.theatlantic.com/ideas/archiv...

We finished the week by welcoming @lochlanfennell.bsky.social (UniSC 🇦🇺) for an Impromptu Seminar on the spatial tumour–immune microenvironment in #ColorectalCancer 🧬 Thank you, Lochlan, for an insightful presentation & engaging discussion, & to our host, CeMM PI @andre-rendeiro.com!

🚨 New preprint: The Spatial Atlas of Human Anatomy
Jiwoon Park et al @ Chris Mason's lab present the first multimodal, subcellular-resolution reference of human tissues across organs.

15M cells from >100 donors profiled with CosMx, Xenium, GeoMx, snRNA-seq and more: www.biorxiv.org/content/10.1...

Open Positions CeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences

🚨 3 days left to apply!
Join us at CeMM (Vienna) to work on AI + computational pathology projects like LazySlide.
Amazing team, H100 GPUs, real impact.
Apply now: cemm.at/join-cemm/op...

Open Positions

🚨 We are recruiting at CeMM! If you're excited about tools like LazySlide and want to work at the interface of computational pathology, AI, and molecular medicine, check out the CeMM International Postdoc Program.
cemm.at/join-cemm/op...

Agreed, it will increase competition even more and squeeze out the younger PIs

GitHub - rendeirolab/LazySlide: Accessible and interoperable whole slide image analysis Accessible and interoperable whole slide image analysis - rendeirolab/LazySlide

🛠️ LazySlide is free, open-source, and significantly easier to work with than other tools. Whether you're a pathologist or a single-cell researcher, LazySlide brings WSIs to your fingertips.
github.com/RendeiroLab/...

🧠 Built on the @scverse.bsky.social ‬ecosystem 🐍, LazySlide makes advanced histopathology analysis accessible with minimal code. Segment tissue, classify cells, run vision-language queries or integrate with omics data - all these without training, and in an already familiar API. lazyslide.rtfd.io

🔬 Whole slide histopathology images are a goldmine for tissue biology and diagnostics - but too often locked away in inaccessible formats or tools. In our new preprint, we introduce LazySlide: an open-source, modular, and interoperable framework.
www.biorxiv.org/content/10.1...

GitHub - rendeirolab/LazySlide: Accessible and interoperable whole slide image analysis Accessible and interoperable whole slide image analysis - rendeirolab/LazySlide

🛠️ LazySlide is free, open-source, and significantly easier to work with than other tools. Whether you're a pathologist or a single-cell researcher, LazySlide brings whole slide image analysis to your fingertips. Check it out: github.com/RendeiroLab/...

🧠 Built on the @scverse.bsky.social ‬ecosystem 🐍, LazySlide makes advanced histopathology analysis accessible with minimal code. Segment tissue, classify cells, run vision-language queries or integrate with omics data - all these without training, and in an already familiar API. lazyslide.rtfd.io

Today we had the pleasure of hosting Roman Praschberger (@i-med.ac.at) at #CeMM for an Impromptu Seminar hosted by @andre-rendeiro.com. Roman shared how rare disease genetics & #SingleCell sequencing can uncover neuronal resilience pathways. Thanks for the inspiring talk!

It’s Friday! 🔍Discover the #EquationsForLife from @andre-rendeiro.com's Group: using #LinearRegression & deep learning, they created “tissue clocks” that predict biological age from images & blood!🧬

👉Read more: tinyurl.com/CeMMRR2024-R...

#CeMMResearchReport2024

Welcome AITHYRA!

Congratulations!

Atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses - Nature Medicine This study provides a cross-trait atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses.

Pujol Gualdo, N., Džigurski, J., Rukins, V. et al. Atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses. Nat Med (2025). doi.org/10.1038/s415...
^^ super important research and some great insights and polygenic risk scores with broad applicability

Simultaneous immunomodulation and epithelial-to-mesenchymal transition drives lung adenocarcinoma progression Lung cancer remains the deadliest cancer in the United States, with lung adenocarcinoma (LUAD) as its most prevalent subtype. While computed tomography (CT)-based screening has improved early detectio...

How well do CT scans predict the aggressiveness of early lung lesions? 🫁

Imaging >60 proteins in >2M cells, we compare CT and histology classes in very early lesions, and show fibrosis and EMT-driven changes missed by CT.
#lungcancer #cancerresearch

doi.org/10.1101/2025...

I am curious about your opinion and feedback, please reach out!

Excited to announce that the Rendeiro Lab Manual is now open source! Inspired by other labs, the information we need to work efficiently and collaborative is now available to everyone: rendeiro.group/lab-manual/ (source available here: github.com/rendeirolab/...)