Nathan Markarian

Predicting Plasmodium drug resistance through in vitro evolution Knowledge about the resistibility and targets of compounds critically informs antimalarial drug development. Luth et al. systematically analyzed the resistome of Plasmodium falciparum through in vitro...

Of all the -omes neologisms, i think Resistome is my favourite one! www.cell.com/trends/paras...

Mediterranean Spotted Fever: Current Knowledge and Recent Advances Mediterranean spotted fever (MSF) is an emerging tick-borne rickettsiosis of the spotted fever group (SFG), endemic in the Mediterranean basin. By virtue of technological innovations in molecular gene...

Rickettsia conorii causes Mediterranean spotted fever (MSF), endemic in the Mediterranean basin. Transmitted by the brown dog tick, Rhipicephalus sanguineus, MSF presents with fever, rash, and an eschar ("tache noire"). Doxycycline is the treatment of choice.
pmc.ncbi.nlm.nih.gov/articles/PMC...

YouTube video by MicrobeTV TWiV 1195: Dickson Despommier, parasitologist without borders

TWiV 1195 is a tribute to our late co-host Dickson Despimmier 🤍 youtu.be/2PRYLYwgCmo?...

YouTube video by MicrobeTV TWiP 253: Sub-Saharan somnolence

youtu.be/SJKoN-noogY?...

Clinical update with Dr. Daniel Griffin Podcast Episode · This Week in Virology · 02/22/2025 · 59m

podcasts.apple.com/us/podcast/t...

Guess the pathogen! Part 6

Burkholderia pseudomallei and melioidosis - Nature Reviews Microbiology In this Review, Meumann et al. discuss current knowledge on Burkholderia pseudomallei virulence and interaction with the host, and examine the epidemiology of melioidosis, offering insights into diagn...

Burkholderia pseudomallei is a Gram-negative, motile rod that causes melioidosis, found in tropical and subtropical regions. Climate change may increase cases. It spreads via environmental exposure, with diabetes and low socioeconomic status as risk factors. www.nature.com/articles/s41...

Guess the pathogen! Part 5

Histoplasmosis: A systematic review to inform the World Health Organization of a fungal priority pathogens list Abstract. Histoplasmosis, a significant mycosis primarily prevalent in Africa, North and South America, with emerging reports globally, poses notable healt

Histoplasmosis, a fungal infection, is caused by inhaling H. capsulatum spores from contaminated soil (bird/bat droppings). Often mild or asymptomatic, it is severe, even fatal, in immunocompromised individuals, like those with HIV/AIDS or transplant recipients.
academic.oup.com/mmy/article/...

Guess the pathogen! Part 4

Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen In this review, we provide updates on Sin Nombre virus (SNV) and other New World hantaviruses. We discuss the history of SNV, its biology and relatedness to other emerging New World hantaviruses, its ...

Sin Nombre virus (SNV), discovered in the U.S. Four Corners region, causes hantavirus pulmonary syndrome (HPS), a life-threatening disease. It is carried by deer mice & transmitted through aerosolized rodent excreta. Symptoms include fever & respiratory distress. pmc.ncbi.nlm.nih.gov/articles/PMC...

Guess the pathogen! Part 3 🦠

Onchocerca volvulus is a filarial nematode that causes onchocerciasis, commonly known as river blindness. Transmitted through the bite of infected blackflies, It primarily occurs in sub-Saharan Africa, with foci in Latin America and in the Middle East.

www.cdc.gov/dpdx/onchoce...

Guess the pathogen! Part 2

Carrion’s disease: more than a neglected disease - Parasites & Vectors Infections with Bartonella bacilliformis result in Carrion’s disease in humans. In the first phase of infection, the pathogen causes a hemolytic fever (“Oroya fever”) with case-fatality rates as high ...

Here's a great review on the topic : parasitesandvectors.biomedcentral.com/articles/10....

"Bartonella bacilliformis infection results in Carrion's disease in humans. In the 1st phase of infection it causes a hemolytic fever "Oroya fever" with a case fatality rate of 90% in untreated patients, followed by a chronic phase resulting in angiogenic skin lesions (verruga peruana)."

Yup! Bartonella bacilliformis :)

Guess the pathogen! Part 1

Good way to learn :)

Frontiers | The latest advancements in Sosuga virus (SOSV) research

Our latest mini-review from this summer, where we explore recent advancements in researching Sosuga virus—a relatively new paramyxovirus identified in a biologist who fell ill after returning from Africa in 2012.

www.frontiersin.org/journals/mic...