The Genetic Links to Anxiety and Depression Study

📣 Everyone 16+ is invited to help us find the genetic links to #anxiety and #depression!
UK @gladstudy.bsky.social needs people with no history of #MentalHealth conditions as well as those who have, to compare.
Take part with @cpft-nhs.bsky.social and help others for #BlueMonday: ➡️ gladstudy.org.uk

🚨NEW PREPRINT ALERT!🚨

Jacob Knyspel investigated the moderating impact of exposure to different traumas on genetic risk for PTSD, using data from @ukbiobank.bsky.social, @gladstudy.bsky.social, @edgiuk.bsky.social and @nihrbioresource.bsky.social

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www.researchsquare.com/article/rs-8...

Difficult-to-treat depression (sometimes called treatment-resistant depression) affects a large proportion of people living with depression. Many patients don’t respond fully to antidepressants, and… Lithium versus Quetiapine in Depression: the results of the LQD study

If you live with depression, you’ll know treatment doesn’t always work.

About half of people still have symptoms, even after more than one medication.

🧵 THREAD

#DifficultToTreatDepression #TreatmentResistantDepression

buff.ly/BtJ3ydR

💙

Whatever you're carrying, you don't have to carry it alone.

Share the load. We're here.

Talk to us:

Support line: 0300 102 1234
open 9am-6pm, Monday - Friday

Email us:
info@mind.org.uk

Contact your local Mind:
find yours on our website

Use our online forum:
Side By Side

'Self-care' in a jug being poured into a cup that says 'you can't pour from an empty cup'

Time to refill that cup

P.S. search 'self-care' on our website for lots of tips and ideas for how

How can I help someone if they're struggling? offer practical help like chores ( laundry basket) educate yourself look for helpful info ( laptop with mind webpage) offer to go to appointments with them (hugging) ask them how they'd like to be supported (How can I help? sign) listen and don't judge (phone) Same time next week, keep social contact (mugs of tea)

It’s tough seeing someone you care about going through a hard time - you can feel pretty helpless, right? 😔
But the good news is, there are ways you can try to support them. 1/2

Can VR help treat anxiety and phobias? New evidence says yes — but with caveats.

A new meta-analysis suggests immersive VR is better than no treatment and often as good as other therapies, especially for anxiety-related disorders.

🧵 THREAD

📣 Now everyone 16+ is invited to help us find the genetic links to #anxiety and #depression!
The UK @gladstudy.bsky.social is also recruiting people with no history of #MentalHealth conditions to compare data with others who have them.
Take part & say you heard about it from CPFT: ➡️ gladstudy.org.uk

Tackling social determinants will reduce the global mental health burden: mega-blog by Xiaolin Guo &‪ @nhigsonsweeney.bsky.social of current prevention strategies buff.ly/niIxj5p

Summarising a recent review by @kirkbride.bsky.social‬ et al

#SocialDeterminants #MentalHealth #Prevention

🧵 THREAD

Excited about our new preprint: 1st successful genome-wide study of >61,000 panic attack and 29,000 panic disorder cases. www.medrxiv.org/content/10.1... We find 17 associations & evidence that peripheral neurons in eye, lungs and heart are involved in panic & other psychiatric disorders 1/n

Thanks to all our participants who generously gave their time and DNA to our studies - from me particularly to the
@gladstudy.bsky.social GLAD study participants.

New research from @kingsioppn.bsky.social @nihrbioresource.bsky.social has identified a range of weight loss behaviours associated with #eatingdisorders which are not currently included in assessment criteria: www.maudsleybrc.nihr.ac.uk/posts/2025/j...

📽️First author Saakshi Kakar explains:👇

(2/2) In a preprint led by @megsk.bsky.social @thaliaeley.bsky.social in @gladstudy.bsky.social, GWASs of #functionalimpairment, anxiety, and depressive symptoms revealed high genetic correlations, suggesting symptom measures may detect most of the genetics of functional impairment. 🔍 osf.io/4d6ju

(1/n) 🔍 Can we predict who will experience antidepressant side effects?

New study led by Danyang Li used machine learning in @gladstudy.bsky.social to predict side effects & discontinuation across SSRIs, SNRIs, and tricyclic antidepressants in over 4,000 participants.

A Spotlight On: Genetics and Mental Health – Gerome Breen - Front Line Genomics Gerome Breen, Professor of Psychiatric Genetics, King’s College London talks about the genetics of mental health, depression and anxiety.

💬 Interested in learning more about @gladstudy.bsky.social? Check out this interview with Study Lead @psychgenomics.bsky.social & how this is a unique dataset to understand genetics & comorbidity between different types of anxiety & depressive disorders.

frontlinegenomics.com/a-spotlight-...

📣 We offer a range of #MentalHealth #research studies to consider taking part in for #MentalHealthAwarenessWeek!
Anyone 16+ in the UK can join the @gladstudy.bsky.social to help find genetic links to #depression & #anxiety and improve treatments - no diagnosis required:
➡️ gladstudy.org.uk
#MHAW25

YouTube video by Mental Elf Targeting underserved regions and communities with mental health research

🎯 We need to target underserved regions and communities with mental health research.

Watch our video to find out how this is happening right now! 👇🏽👇🏽👇🏽

#MentalHealthAwarenessWeek
#MentalHealthResearch

youtu.be/rKTvMtY8Vco?...

Involving people from all communities in mental health research We need to involve people from all communities in mental health research. It’s #MentalHealthAwarenessWeek and the theme this year is COMMUNITY.In the past, m...

We need to involve people from all communities in mental health research.

It’s #MentalHealthAwarenessWeek and the theme this year is COMMUNITY.

🧵 THREAD

Next Week is Mental Health Awareness Week. Mental health is everything, everywhere, everyone. Join the fight with us next week Monday 12 May to Sunday 18 May, so no mind gets left behind.

Just one week to go until Mental Health Awareness Week and this year we’re highlighting that mental health is connected to everything. That means any way you choose to spread the word this Mental Health Awareness Week will make a difference. #MentalHealthAwarenessWeek #MHAW

Listen to the Statistical Genetics Lead of #GLADStudy, @jonicoleman.bsky.social discuss #depression below ⤵️

Dark blue background with snowy features (snowy hill, trees, snowflakes), GLAD logo and study website. Text reads genetic links to anxiety and depression, GLAD, gladstudy.org.uk, it’s getting darker outside… What could this mean for our minds?

Dark blue background with snowy features (icicles and trees), GLAD logo and study website. Text reads genetic links to anxiety and depression, GLAD, gladstudy.org.uk, As we tilt away from the sun during the winter months, we receive less light and colder weather. For some, this can mean having low moods, sleeping longer than normal, and often feeling lethargic. In some cases, seasonal affective disorder occurs (SAD). MET Office, NHS (2021)

Dark blue background with snowy features (icicles and trees), GLAD logo and study website. Text reads genetic links to anxiety and depression, GLAD, gladstudy.org.uk, SAD symptoms include but are not limited to: NHS (2021) A loss of pleasure or interest in normal everyday activities, Irritability, Feelings of despair, guilt and worthlessness, Finding it hard to get up in the morning, Difficulty concentrating. Whilst not everyone suffers from SAD, the winter season can be hard regardless. What can we do to help with this?

Dark blue background with snowy features (icicles and snowflakes as textboxes), GLAD logo and study website. Text reads genetic links to anxiety and depression, GLAD, gladstudy.org.uk, Keep a diary and prepare for difficult times, Dedicate time to your physical health, Reach out to loved ones, let them know how you are feeling, Plan relaxing activities, Talk to a medical professional, Take extra time for self-care, Get out whilst the sun is out, alone or with friends, Mind (2022)

The winter season brings along darker skies, but what does this mean for our mental health?

Read here about the signs that it may be more than just the winter blues, and reach out for support if you need it.

(Samaritans, Campaign Against Living Miserably (CALM), SANEline)

gladstudy.org.uk

beige/yellow background with blue, black and white squiggly lines and rectangles with text in. Text reads sign ups, in 2024, 10,388 participants signed up! That’s an 18% increase since 2023!, genetic links to anxiety and depression, GLAD, gladstudy.org.uk

beige/yellow background with blue, black and white squiggly lines, numbers 1-5 with text and small images (hands raised, checklist, party hat, groups of people, silhouette of a group) alongside them. Text reads:Our top GLAD moments Celebrating our 6th anniversary! Welcoming participants without anxiety and depression. Launching two new campaigns to prioritise recruitment of underserved communities. Enhancing our research with deeper insights from our Patient and Public Involvement (PPI) panel. Welcoming 2,000 more participants into our GLAD community this year. Genetic links to anxiety and depression, GLAD, gladstudy.org.uk

beige/yellow background with blue, black and white squiggly lines and rectangles with text in. text reads: number of kits, in 2024 GLAD received 2269 saliva kits. That’s a 6.6% increase since 2023! Genetic links to anxiety and depression, GLAD, gladstudy.org

beige/yellow background with blue, black and white squiggly lines, numbers 1-5 with text and small images of our top posts alongside them. Text reads: our top posts, Even though Eeyore was depressed...Bed Rotting. Now recruiting control participants. Hair Depression. ADHD. genetic links to anxiety and depression, GLAD, gladstudy.org.uk

Everyone’s posting their #SpotifyWrapped, but here’s the GLAD wrapped 2024! 📚🔬

We cannot thank you enough for all of your support🎉

If you would like to join us and be part of our next Wrapped, visit gladstudy.org.uk

Pastel yellow and blue background with graphics of flying books, clouds, and a brain with glasses reading a book while sitting on a cloud. Dark blue text, “Want to learn a bit more about anxiety and depression? GLAD to read…” in the centre. GLAD logo in the top right corner.

Pastel yellow and blue background with dark blue text, “When Things Fall Apart: Heart Advice for Difficult Times by Pema Chödron. A book where each chapter is only six pages, so you take in a little at a time at your own pace. By normalising anxiety, you can feel less alone” in the centre. GLAD logo in the bottom right corner and dark blue text, “gladstudy.org.uk” in a white text box in the bottom left corner. Graphic of the book cover to the left.

Pastel yellow and blue background with dark blue text, “Big Magic: Creative Living Beyond Fear by Elizabeth Gilbert. A book with short, concise chapters that may be a breath of fresh air for perfectionists. Explore letting go and embracing curiosity” in the centre. GLAD logo in the bottom right corner and dark blue text, “gladstudy.org.uk” in a white text box in the bottom left corner. Graphic of the book cover to the left.

Want to read more about anxiety and depression📚?

Check out our book suggestions to inspire creativity and embrace life’s journey✨

Let us know your recommendations!

gladstudy.org.uk

#mentalhealthmatters #anxietybooks

@kingscollegelondon.bsky.social @nihr.bsky.social @nihrmaudsleybrc.bsky.social @psychgenomics.bsky.social @thaliaeley.bsky.social

Hi all! We're the GLAD Study, the world's largest study of anxiety and depression

We welcome anyone 16+ living in the UK with #depression, #anxiety or no experience of #mentalhealthdisorders to sign up to make a change in mental health research

Join us: gladstudy.org.uk

We are grateful to our funders, study teams, and users over the years. These days, there is an impressive range of discoverability platforms, and we are happy that we can still support researchers with the #CatalogueMHM.🧵4/5
@gladstudy.bsky.social @usociety.bsky.social @clscohorts.bsky.social

YouTube video by Eating Disorders Genetics Initiative The Eating Disorders Genetics Initiative (EDGI) Information Video

Hi BlueSky!

We're EDGI UK, an online research study exploring the genetic and environmental influences of all eating disorders

Our study is open to anyone
⭐16+
⭐residing in England
⭐Has ever experienced an eating (diagnosis not required)

Join today: edgiuk.org

Huge welcome to the Bluesky accounts of the world's largest cohort studies of anxiety and depression, and eating disorders

@gladstudy.bsky.social and @edgiuk.bsky.social

🧪 #episky #PsychSciSky #neuroskyence #devpsych #Medsky