Genshiro A. Sunagawa

Influence of poly(A) sequences and genetic elements on iCre expression and induction of a hibernation-like state in mice - Journal of Comparative Physiology B Journal of Comparative Physiology B - Activation of hypothalamic QRFP-producing neurons (Q neurons) induces a hibernation-like state in mice, termed Q neurons–Induced Hypometabolism (QIH). To...

While improving a mouse QIH (synthetic torpor–like) model, we found that changing the polyA sequence downstream of a knock-in iCre caused unexpectedly large shifts in expression patterns. A modest observation, but useful for generating mouse lines with brain Cre expression.
doi.org/10.1007/s003...

An excellent resource for learning both the concepts and practical use of Bayesian statistics, especially for researchers working with real data.

The major difference this time is that he’s running two parallel tracks each week: Beginner and Experienced. The plan is to cover the entire Statistical Rethinking, 2nd edition by March.

YouTube video by Richard McElreath Statistical Rethinking 2026 - Lecture A01 - Introduction to Bayesian Workflow

Richard McElreath @rmcelreath.bsky.social has started releasing his new Statistical Rethinking (2026) lectures — I think this is the first update in about three years.
www.youtube.com/watch?v=ztbY...

YouTube video by Richard McElreath Statistical Rethinking 2026 - Lecture A01 - Introduction to Bayesian Workflow

Richard McElreath さんの 『Statistical Rethinking（2026）』新講義が公開され始めた（3年ぶりだと思う）。今回の大きな違いは、 Beginner / Experienced の2トラックを毎週“並走”させる点。3月までに Statistical Rethinking 2ed をカバーする構成。ベイズ統計の概念や実践的な手法を学ぶのにとても良い教材だと思います！
www.youtube.com/watch?v=ztbY...

The International Hibernation Society is happy to release the Seasonal Hibernation Highlights for the Fall 2025.

Enjoy reading the latest research on Torpor & Hibernation as Seasonal Adaptative Strategies and as Biomimicry Inspiration!

@sicbjournals.bsky.social @sebiology.bsky.social

The International Hibernation Society starts to release quaterly Seasonal Highlights on the Topic "Torpor & Hibernation as Seasonal Adaptative Strategies".

Here are the first Hibernation Highlights for the Summer 2025. Enjoy reading the latest research from the Torpor & Hibernation field!

Quaterly Hibernation Highlights will be available on the IHS Website: hibsoc.com

The PDF of the 2025 Summer Hibernation Highlights are accessible from this link : hibsoc.com/wp-content/u...

Stay Tuned 😀 🙃 😁

Synthetic torpor: advancing metabolic regulation for medical innovations - Nature Metabolism Chen et al. provide an overview of historical and more recent approaches for the induction of synthetic torpor, and discuss their potential medical applications.

Our new review in Nature Metabolism explores the emerging science of synthetic hibernation. From neural circuits to organ protection, mild hypothermia to lifespan modulation. A guide for those venturing into the field.
👉 nature.com/articles/s42...
#SyntheticTorpor #Hibernation #TranslationalMedicine

These are real images of exoplanets.

Four super-Jupiters, imaged 10 times over 12 years around a star 133 lightyears away.

These are real, giant worlds, out there in the dark.

And we can see them.

YouTube video by 進化生物学ch【ゆっくり解説】 【ゆっくり解説】人工冬眠の可能性【 進化論 / 科学 】

🎉 Evolutionary Biology Channel featured synthetic hibernation!! ❄️🐻✨
They explained QIH and its applications so clearly—I'm super happy! 😆💖
"Hibernation research, standing on the shoulders of giants, will only speed up from here!" 🚀🌍
#ゆっくり解説
www.youtube.com/watch?v=a7c5...

Why we (usually) don't have to worry about multiple comparisons Applied researchers often find themselves making statistical inferences in settings that would seem to require multiple comparisons adjustments. We challenge the Type I error paradigm that underlies t...

Since it is inefficient to attempt to educate every reviewer individually, I am yeeting into your feed this clear paper from Gelman, Hill, and Yajima on how Bayesians can do even better than correcting for multiple comparisons. arxiv.org/abs/0907.2478

新作をリリースすることが一番の宣伝。ひとりで7年間，ゲームを作ってきた個人開発者が心がけていたこととは［IDC2024］ IDC2024にて「ひとりで7年ゲームを作ってきた開発者の生存術」というセッションが行われた。このセッションは，個人開発者のじぃーま氏が自身のゲーム開発経験を振り返って，大切だと感じたことを共有するものだ。

At IDC2024, solo developer Jiima shared how he uses errors as a tool: by stopping work at a "rough point," errors help him quickly resume tasks. This, along with regular game releases and unified themes, has fueled his success in seven years of solo game development.
www.4gamer.net/games/529/G0...