Rahul K's Avatar

Rahul K

@theresearch.bsky.social

I run, ski, and engineer cells and materials; asking how nutrient sensing & signaling work: bit.ly/RK-GoogleScholar ๐Ÿ‡ช๐Ÿ‡ช: TalTech| Ex: Tartu รœlikool; ๐Ÿ‡ธ๐Ÿ‡ช: Karolinska Institutet, Chalmers; ๐Ÿ‡ฏ๐Ÿ‡ต: Kyutech; ๐Ÿ‡ฎ๐Ÿ‡ณ: IITD

1,902 Followers  |  643 Following  |  292 Posts  |  Joined: 28.11.2023  |  2.1027

Latest posts by theresearch.bsky.social on Bluesky

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Want to analyze the role of endogenous retroviruses in early human development or investigate their regulation in pluripotency and early development for your PhD?

Join the lab of @fueyoraquel.bsky.social via the IMPRS-BAC #gradschool!

๐Ÿ‘‰ www.molgen.mpg.de/5094682/Fuey...

27.11.2025 14:06 โ€” ๐Ÿ‘ 20    ๐Ÿ” 17    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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๐Ÿ“†Save the Date๐Ÿ“†

Our Metabolism in Health & Disease conference returns from 10-13 Oct 2026 - this time in Portugal!

Keep informed about speaker announcements, grant & abstract opportunities by signing up for updates here: bit.ly/MHD26-SaveTh...

@petemullen.bsky.social @annakrook.bsky.social

02.12.2025 16:44 โ€” ๐Ÿ‘ 6    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Project Assistant The Department of Medical and Translational Biology at the Faculty of Medicine is now seeking a project assistant for a research project related to human brain aging. The position is full-time and lim

๐Ÿ“ฃWe are looking for a Project Assistant to join my group at the Wallenberg Center for Molecular Medicine at Umeรฅ University. Join us if you are interested in transposable elements, epigenetics and human brain aging. ๐Ÿง ๐Ÿงฌ Dont hesitate to reach out with any questions! ๐Ÿ“ฃ
umu.varbi.com/en/what:job/...

06.12.2025 20:06 โ€” ๐Ÿ‘ 8    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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A vision of chromosome organization Cryogenic electron tomography of condensed chromatin enables multiscale analysis of its structure

Cryogenic electron tomography of condensed chromatin enables multiscale analysis of its structure.

Learn more in a new #SciencePerspective: https://scim.ag/3Yfn1T3

09.12.2025 20:36 โ€” ๐Ÿ‘ 40    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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Confused by all the histones that are cropping up in organisms that are decidedly NOT eukaryotes? check out our review - fantastic work by team NucEvo in the #Lugerlab
The Expanding Histone Universe: Histone-Based DNA Organization in Noneukaryotic Organisms - www.annualreviews.org/content/jour...

09.12.2025 15:14 โ€” ๐Ÿ‘ 160    ๐Ÿ” 74    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 3
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Please RT ๐Ÿ“ง
Registration open for โžก๏ธ"Summer School on Chromatin Biology" Our 2 weeks hands on expedition ๐Ÿงช๐Ÿ‘ฉโ€๐Ÿ’ปAugust 2026. 3. edition. Learn CUT@Tag, CUT@Run, ChIPseq, ATACseq AND to analyse your own data at @helmholtzmunich.bsky.social Daily letures by experts in the field !

โ–ถ๏ธ shorturl.at/jrA8i

09.12.2025 11:59 โ€” ๐Ÿ‘ 10    ๐Ÿ” 11    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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So, what have we learned about #SkeletalMuscle?

While cytoskeletal organization is very similar, there are marked differences in the use of FoxO signaling and amino acid metabolism. Cell models reflect most but not all signatures of tissue myocytes, so important which one to choose #MyoBlue.

08.12.2025 09:49 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

The story of how multiple RBPs cooperate to repress translation is now out in @cp-cellreports.bsky.social by @marcopayr.bsky.social and in a great collaboration with @hennig-lab.bsky.social!

www.cell.com/cell-reports...

07.11.2025 15:34 โ€” ๐Ÿ‘ 39    ๐Ÿ” 13    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
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โœจNew preprint!

๐Ÿงต1/4 Excited to share our work on AI-guided design of minimal RNA-guided nucleases. Amazing work by @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social et al!
Multi-lab collaboration @banfieldlab.bsky.social @jhdcate.bsky.social @jacobsenucla.bsky.social๐Ÿงฌ

๐Ÿ”—๐Ÿ‘‡

09.12.2025 07:52 โ€” ๐Ÿ‘ 86    ๐Ÿ” 44    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 8

Anybody got an example of substrate channeling where an isotopic label in a specific product is more enriched than the tracer? I know this is theoretically possible with compartmentalized pools but I am drawing a big old blank on relevant literature?

09.12.2025 00:24 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Lead a lab at Janelia

Janelia is hiring! "Invent new imaging methods, molecular tools, or protein chemistry approaches"

www.janelia.org/content/lead...

08.12.2025 20:41 โ€” ๐Ÿ‘ 28    ๐Ÿ” 22    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Synthetic cells by the numbers Mathematical biosciences; Experimental models in systems biology; Synthetic biology

Latest issue of curated #engineeredlivingmaterials feed:
biomed.news/bims-enlima/... #ELMs
via @biomednews.bsky.social #livingmaterials

includes research on: synthetic cells, ELMs design principles, muscle-powered robots, & more ๐Ÿงช

07.12.2025 10:35 โ€” ๐Ÿ‘ 4    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Come to be our colleague! Center of Paris, excellent facilities, research spanning the whole range of basic and biomedical life science topics, enthusiastic and collaborative colleagues, crรจme brรปlรฉe every Friday... What else could one want?

08.12.2025 10:56 โ€” ๐Ÿ‘ 33    ๐Ÿ” 30    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
Job profile

We have an exciting postdoc position supported by MRC funding to study the interplay between epigenetics and cellular metabolism in human ESCs.

Application deadline January 5th of January 2025.

hrwebapp.qub.ac.uk/tlive_webrec...

www.atlasilab.com

08.12.2025 12:13 โ€” ๐Ÿ‘ 5    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

We will announce a #postdoc opening in January. Cryo-ET and virus replication. If you're interested you can DM or email me already now. More info will follow!

08.12.2025 17:44 โ€” ๐Ÿ‘ 9    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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FEBS Press The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the hear....

Our new review: Hematopoietic (stem) cellsโ€”The elixir of life? ๐Ÿง
Rejuvenation of the blood system might also improve the health of other organs! #FEBS Letters
Link to final video: lengefeldlab.com?page_id=203
Please RT. Happy reading ๐Ÿ˜ƒ
febs.onlinelibrary.wiley.com/doi/10.1002/...

08.12.2025 18:52 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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A genetic platform for a biocementation bacterium Sporosarcina pasteurii is the most widely studied bacterium for microbially-induced calcium carbonate precipitation (MICP), a process of intense interest for materials and construction applications. D...

The #1 organism used to make biocement has never been engineered... until now! Excited to share our work on Sporosarcina pasteurii! Esp. since it's the first project I've contributed to here at Cultivarium :)

www.biorxiv.org/content/10.6...

08.12.2025 14:24 โ€” ๐Ÿ‘ 23    ๐Ÿ” 12    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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A cellular cross-species RNA-seq atlas captures the transcriptional dynamics of myogenesis Skeletal muscle formation and regeneration is a tightly regulated process involving extensive transcriptional reprogramming as proliferating myoblasts fuse into mature myotubes. However, a comparative...

๐Ÿšจ New #MyoBlue preprint: Today, we report a cellular cross-species RNA-seq atlas of myogenesis - using mouse & human cell culture models combined with in vivo snRNA-seq from muscle we provide a comprehensive resource for investigating #SkeletalMuscle differentiation.

www.biorxiv.org/content/10.6...

08.12.2025 09:26 โ€” ๐Ÿ‘ 24    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

New to RNA design? Please try pyFuRNAce! Looking forward to your feedback ๐Ÿงฌ

07.12.2025 16:39 โ€” ๐Ÿ‘ 19    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Uniform pre-processing of bacterial single-cell RNA-seq https://www.biorxiv.org/content/10.64898/2025.12.04.692398v1

07.12.2025 02:46 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

A genetic platform for a biocementation bacterium https://www.biorxiv.org/content/10.64898/2025.12.05.692644v1

07.12.2025 02:02 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

What an honor to see @attychang.bsky.socialโ€™s work featured in @jcb.org The Year in Cell Biology 2025 collection! Even more special that it coincides with my first #cellbio2025 conference ๐Ÿ™‚

s/o to co-authors @baradlab.com @hamid13r.bsky.social @zidlab.bsky.social

#teamtomo #cellbio25

07.12.2025 20:10 โ€” ๐Ÿ‘ 44    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling Protein glycosylation regulates essential cellular processes including protein folding, stability, and cell-cell interactions; however, how aberrant glycosylation impacts protein function and interact...

Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale ๐Ÿ‘

www.biorxiv.org/content/10.6...

08.12.2025 02:32 โ€” ๐Ÿ‘ 81    ๐Ÿ” 25    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
https://www.cell.com/cms/10.1016/j.cell.2025.11.002/asset/6a29b9bb-e6a4-4eb7-a86a-b1f1f5fd697f/main.assets/fx1_lrg.jpg

https://www.cell.com/cms/10.1016/j.cell.2025.11.002/asset/6a29b9bb-e6a4-4eb7-a86a-b1f1f5fd697f/main.assets/fx1_lrg.jpg

Such a great collection of papers on #mitochondrialdisease from #week49! ๐Ÿ“š Congratulations to all authors! biomed.news/bims-mitdis/...
@biomednews.bsky.social @mitoscientist.bsky.social

Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
Wang et al

07.12.2025 14:54 โ€” ๐Ÿ‘ 13    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis Zheng et al. demonstrate that mitochondria remodel the structure and composition of mitochondrial ribosomes in response to metabolic state. This structural โ€œgear-switchingโ€ mechanism fine-tunes mitoch...

Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis

www.cell.com/molecular-ce...

07.12.2025 17:04 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Looking forward the 2025 Nobel Lectures in Physiology or Medicine today at Karolinska Institutet

Congratulations to the Laureates

Professor Shimon Sakaguchi

Dr Mary E. Brunkow

Dr Fred Ramsdel

For info on the lectures see link:

news.ki.se/calendar/the...

07.12.2025 12:50 โ€” ๐Ÿ‘ 8    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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The Nobel Prize Physiology lecture about to start!
www.nobelprize.org

07.12.2025 12:44 โ€” ๐Ÿ‘ 46    ๐Ÿ” 5    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Biohybrid Tendons Enhance the Powerโ€toโ€Weight Ratio and Modularity of Muscleโ€Powered Robots Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscleโ€“tendon architecture by leveraging toug....

Biohybrid Tendons Enhance the Power-to-Weight Ratio and Modularity of Muscle-Powered Robots (h/t @rituraman.bsky.social) #biorobotics

07.12.2025 10:35 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@theresearch is following 20 prominent accounts