The Mario 64 intro scene with a letter from Princess Peach, reading: Dear Mario. Please come to the castle. I'm down bad. Yours truly-- Princess Toadstool (Peach)
CATS from the video game Zero Wing (the All Your Base Are Belong To Us game), saying: "I am Locutus of Borg. Resistance is Futile"
Dracula from Castlevania: Symphony of the Night, saying to Richter "Get out of my house"
The transportation advisor from SimCity 2000, saying "YOU CAN'T STAY ON TWITTER! YOU WILL REGRET THIS!"
My big project: The Death Generator.
It's a tool for making fake video game screenshots, just fill in new text and it'll give you a (generally) pixel-accurate image back, the correct fonts and everything.
deathgenerator.com