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Bogi

@zbobo2.bsky.social

19 Followers  |  16 Following  |  3 Posts  |  Joined: 06.06.2025  |  1.2863

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๐Ÿงฌ New paper in Nature Communications!
We found that POLE2,part of DNA polymerase ฮต,moonlights as a receptor for NPF motifs, binding 70+ proteins across replication, transcription & repair.
The interactome is more interconnected than thought.
@teamgogl.bsky.social ๐Ÿ‡ซ๐Ÿ‡ฎ๐Ÿ‡ซ๐Ÿ‡ท๐Ÿ‡ญ๐Ÿ‡บ๐Ÿ‡ฌ๐Ÿ‡ง

www.nature.com/articles/s41...

15.12.2025 11:58 โ€” ๐Ÿ‘ 8    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
The non-catalytic DNA polymerase ฮต subunit is an NPF motif recognition protein - Nature Communications Short linear motifs in disordered protein regions are involved numerous proteinโ€“protein interactions. Here, the authors find that the POLE2 subunit of human DNA polymerase ฮต acts as a motif binding pr...

Happy to share that our paper describing a new motif-mediated interactome is out in Nature Communications

www.nature.com/articles/s41...

15.12.2025 08:40 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
ProfAffv2 - Protein Affinity Database

profaff.fr

The new ProfAff database is up and running. Although there are still many things to improve, it is a major upgrade.

28.10.2025 08:04 โ€” ๐Ÿ‘ 6    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I am also deeply grateful to the many colleagues, mentors and friends who have supported me at various stages of my scientific journey - too many to name individually, but I deeply appreciate them all.

12.06.2025 08:51 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I am sincerely grateful to the committee for entrusting me with this opportunity. I owe a lot to the incredible team at iBV, whose unwavering support and guidance has been instrumental in preparing me for the interview.

12.06.2025 08:51 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Iโ€™m thrilled to share that I have secured a permanent position within Section 20 of the CNRS. I will do my utmost to advance our understanding of the intricate interactome of transcription factors, an area of research I am deeply passionate about. ๐ŸŽ†

12.06.2025 08:49 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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We like our proteins pure. This is the first #mCherry purification in the new lab. The next ones will be less colorful, I am afraid...

10.06.2025 14:24 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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