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Mike Morgan

@mdmorgan.bsky.social

Lecturer (assistant professor) University of Aberdeen. Immunology, computational biology, genetics and single cells. Runner, climber and connoisseur of Yorkshire tea. Views expressed are my own. https://www.morganlab.co.uk/

1,155 Followers  |  1,818 Following  |  37 Posts  |  Joined: 18.09.2023  |  2.2277

Latest posts by mdmorgan.bsky.social on Bluesky

AllTheBacteria

Small update from AllTheBacteria (allthebacteria.org). Assemblies can be bulk downloaded from OSF as before, or you can now get individual assemblies from AWS. We now also have a LexicMap index on AWS, so you can align your favourite gene against 2.4million bacteria (next post for price estimates)

29.04.2025 15:36 โ€” ๐Ÿ‘ 47    ๐Ÿ” 23    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

On an immunological note, promiscuous expression of reproductive tissue antigens in the thymus might also suggest there is a need for tolerance against these tissues, albeit earlier in life than most cancer patients. What are your thoughts?

30.04.2025 11:50 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Baking in marginal selection of antigens to prevent the adverse loss of reproduction seems a minor inconvenience compared to stopping someone from having kids full stop.

30.04.2025 11:50 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

Saying reproductive tissues are fair game relegates the patient to an object rather than a living breathing person. If that cancer therapy destroys someone's child bearing or producing capacity that is not a good therapy.

30.04.2025 11:50 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Intriguing - maybe worth throwing into the mix that CTAs might need to be sex dependent. Probably not a great idea to give anti-testes CARTs to blokes and anti-placental CARTs to women.

30.04.2025 08:40 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Celebrate International #DayofImmunology by treating yourself to one of our events or training courses! ๐ŸŽ‰

Whether its our Diversity in Immunology event, next weekโ€™s Flow Cytometry training, or the BSI Immunology Awards - there's something for you ๐Ÿ‘€ bit.ly/3v2aAi1

29.04.2025 13:54 โ€” ๐Ÿ‘ 5    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Vaccination in pregnancy to protect the newborn - Nature Reviews Immunology In this Review, Male and Jones provide an overview of the current vaccines that are offered during pregnancy and to newborns, explaining the rationale behind the different vaccination programmes and t...

๐Ÿ‘ถ๐Ÿผ Many #vaccines are not effective in newborns. So how do we protect them from infectious disease?

๐Ÿคฐ๐Ÿฝ By vaccination in #pregnancy!

Here we reviewโ€ฆ

๐Ÿ’‰ Established campaigns vs whooping cough, flu, COVID

๐Ÿ’ก New approaches to RSV, GBS

๐ŸŒˆ Future challenges, opportunities

#ReproSky #ImmunoSky #IDSky

24.04.2025 06:21 โ€” ๐Ÿ‘ 273    ๐Ÿ” 118    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 6
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Today marks the start of #WorldImmunisationWeek! โญ

Get inspired by reading our latest #CelebrateVaccines blog, which explores how the new RSV vaccine is cutting NHS costs and protecting vulnerable populations.

๐Ÿ”— bit.ly/42V1NwZ

#VaccinesWork #HumanlyPossible

24.04.2025 10:54 โ€” ๐Ÿ‘ 5    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Jess read the โ€œdire wolfโ€ preprint so you donโ€™t have to. A long, exasperated and heroic evening thread by someone who knows what they are talking about, which shows the whole thing to be even more flakey than we thought. We salute you, @jfmclaughlin92.bsky.social!

12.04.2025 06:33 โ€” ๐Ÿ‘ 27    ๐Ÿ” 14    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN Dr. Ardem Patapoutian says he watches โ€œwith deep sadness as the United Statesโ€™ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...

Published an op-ed for @cnn.com: โ€œNobel laureate: I owe America my success. Today, its scientific future is in danger.โ€
A personal reflection on whatโ€™s at stake as science funding gets slashed. Iโ€™d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...

09.04.2025 11:30 โ€” ๐Ÿ‘ 903    ๐Ÿ” 494    ๐Ÿ’ฌ 15    ๐Ÿ“Œ 25

Anti-citrullinated protein antibodies arise during affinity maturation of germline antibodies to carbamylated proteins in rheumatoid arthritis https://www.biorxiv.org/content/10.1101/2025.03.22.644346v1

25.03.2025 20:16 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ“† Mark your agenda for the 25th European Conference on Computational Biology! It will take place in Geneva, Switzerland, from 31 August-4 September 2026.

๐Ÿ‘‰ Save the date and stay tuned for more updates as we get ready for #eccb2026

25.03.2025 14:05 โ€” ๐Ÿ‘ 10    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

13 chair positions open @inserm.fr to lead a junior research group in France covering #neuroscience, #immunology, #bioinformatics, #bioengineering, #biotherapy, #public health pro.inserm.fr/rubriques/co... ๐Ÿงช๐Ÿ”ฌ

24.03.2025 20:20 โ€” ๐Ÿ‘ 36    ๐Ÿ” 43    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
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Postdoctoral fellow - Saez-Rodriguez Group Your group Saez-Rodriguez Research Group Your supervisor Julio Saez-Rodriguez Your role As a postdoctoral fellow in the Saez Rodriguez group, you will develop and apply computational methods and tools...

6 days left to apply to the Post-doc opening in our lab
@ebi.embl.org to develop&apply #bioinformatics & #machine-learning methods to study intra-/extra cellular networks to extract disease mechanisms from #single-cell and #spatial multiomic data: embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

17.03.2025 18:01 โ€” ๐Ÿ‘ 31    ๐Ÿ” 27    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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Uncovering bacterial metabolites that can attenuate vitamin B12 deficiency (AKAY_U25MMB) at University of East Anglia on FindAPhD.com PhD Project - Uncovering bacterial metabolites that can attenuate vitamin B12 deficiency (AKAY_U25MMB) at University of East Anglia, listed on FindAPhD.com

We are advertising for a PhD position to study bacterial metabolites in C. elegans, funded by the MRC Microbes, Microbiomes and Bioinformatics training programme @uniofeastanglia.bsky.social @biouea.bsky.social. Open to UK and international students. www.findaphd.com/phds/project...

16.03.2025 10:57 โ€” ๐Ÿ‘ 14    ๐Ÿ” 22    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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How I teach the monogenic disorder PKU with a model and some history of eugenics If you're teaching Mendelian genetics, monogenic disorders are on the cards. But which ones are good examples? The IB has once again decided on PKU (phenylketonuria). In this post, I'll show you how ...

Today I taught about phenylketonuria and eugenics. An important lesson, especially in times of nazis. Blog post:
#iTeachBio #SciTeachUK

cmooreanderson.wixsite.com/teachingbiol...

12.03.2025 18:57 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Four ways COVID changed virology: lessons from the most sequenced virus of all time After 150,000 articles and 17 million genome sequences, what has science taught us about SARS-CoV-2?

Great article from Ewen Callaway in @nature.com about how #SARSCoV2 has helped us better understand viruses - including the areas where we still have much to learn.

โ€œThis was one of the first times where evolutionary biology became an applied scienceโ€ says @jbloomlab.bsky.social

12.03.2025 16:24 โ€” ๐Ÿ‘ 113    ๐Ÿ” 40    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2
Assistant/Associate Professor in Computational Biology - Job Opportunities - University of Cambridge Assistant/Associate Professor in Computational Biology in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge.

We are excited to announce a new faculty position here in Cambridge, for researchers in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Come and join us! Happy to answer questions about research, teaching and working here. www.jobs.cam.ac.uk/job/50414/

21.02.2025 15:07 โ€” ๐Ÿ‘ 313    ๐Ÿ” 240    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 5
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a man is typing on a keyboard in a living room Alt: a man is typing on a keyboard in a living room

Exploring #Proteomics?
Join us for a brand new and improved *Analysing Proteomics Data* #bioinformatics #training course this Wednesday 12th March, live online via Zoom
9:30-17:00 GMT/UTC
www.bioinformatics.babraham.ac.uk/training.html

10.03.2025 09:45 โ€” ๐Ÿ‘ 10    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Reviving the woolly mammoth isnโ€™t just unethical. Itโ€™s impossible | Adam Rutherford At a time when US scientists are under attack from their own government, the illiteracy around these elephantine fantasies is dangerous, says geneticist Adam Rutherford

A mammoth circus of macabre fantasy and moral bankruptcy.
I got my views on mammoths down. Enjoy.

www.theguardian.com/commentisfre...

06.03.2025 14:15 โ€” ๐Ÿ‘ 539    ๐Ÿ” 187    ๐Ÿ’ฌ 37    ๐Ÿ“Œ 32
Postdoctoral Fellowships The information provided on this page is a summary of the main rules and requirements for Postdoctoral Fellowships (PFs) and who can apply for them.

๐Ÿ“ฃ๐Ÿ“ฃAre you looking for a postdoc? ๐Ÿ“ฃ๐Ÿ“ฃ

Does a EU or Horizon Europe assoc country (eg UK, S Korea) seem like a good destination?

These fellowships a great funding option for anyone in the ๐ŸŒŽ

๐Ÿ‘€ Check them out - next call opens 8 May

๐Ÿงช ๐Ÿ‘จโ€๐Ÿ”ฌ๐Ÿ‘ฉโ€๐Ÿ”ฌ
marie-sklodowska-curie-actions.ec.europa.eu/actions/post...

09.03.2025 08:59 โ€” ๐Ÿ‘ 217    ๐Ÿ” 134    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 3
Poster of the EIPOD call

Poster of the EIPOD call

Join the Interdisciplinary Postdoc Fellowship Program at the European Molecular Biology Laboratory (EMBL), one of the best places to do research in modern biology and develop your career.

Great opportunities for statisticians, comp. biologists, AI experts, mathem. modelers!
www.embl.org/eipod-linc

22.11.2024 09:02 โ€” ๐Ÿ‘ 41    ๐Ÿ” 32    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
GSK hiring Computational Biologist in Stevenage, England, United Kingdom | LinkedIn Posted 11:13:48 PM. Site Name: UK - Hertfordshire - Stevenage, Heidelberg - OfficePosted Date: Feb 28 2025We create aโ€ฆSee this and similar jobs on LinkedIn.

Are you a postgraduate student interested in protein modelling and drug discovery?

We have an exciting opportunity to join our team at GSK for a 6-9 months internship, working on an ambitious cross-department research project. Apply before March 14th!

www.linkedin.com/jobs/view/41...

06.03.2025 20:23 โ€” ๐Ÿ‘ 6    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
IMMREP25: TCR Specificity Prediction Challenge Competitors will make predictions on previously unpublished TCR-epitope binding data in order to benchmark prediction methods.

The IMMREP25 TCR specificity prediction challenge is now live on Kaggle!

Get involved: kaggle.com/competitions...

Huge thanks to: Matthew Noakes, @the-dee-em.bsky.social, @everichardson.bsky.social, @bjoernpeters.bsky.social , @adaptivebiotech.bsky.social , IEDB, @airr-community.bsky.social

03.03.2025 14:35 โ€” ๐Ÿ‘ 11    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

PubMed has not been disappeared. It's working fine ๐Ÿ‘‡๐Ÿผ

02.03.2025 11:21 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
BioStudies < The European Bioinformatics Institute < EMBL-EBI BioStudies โ€“ one package for all the data supporting a study

NCBI websites are patchy at present, but now feel far less secure for long-term storage than they used to.

For sequencing datasets consider using ArrayExpress:
www.ebi.ac.uk/biostudies/a...

Many, if not all, GEO datasets are on there.

02.03.2025 09:32 โ€” ๐Ÿ‘ 6    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Future Leaders in Biomedical Sciences Scholarships Open to candidates of Black or mixed Black heritage only.

here's one from us @crick.ac.uk: www.crick.ac.uk/careers-and-...

01.03.2025 14:23 โ€” ๐Ÿ‘ 18    ๐Ÿ” 9    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

The confession of every dog owner

01.03.2025 16:34 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Get 'em up Cairn 'o Mount - that'll get the thighs burning and the lungs busting. If there's no snow...then a whizz down to Balmoral along the Dee.

01.03.2025 11:14 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I am happy to discuss with any American junior researcher about transitioning from PhD>post-doc or PD>PI in Europe. I have experience in this matter! And for those who want to do a PhD, @juliusbrennecke.bsky.social listed a number of outstanding PhD programs in awesome institutes/cities.

01.03.2025 10:50 โ€” ๐Ÿ‘ 30    ๐Ÿ” 19    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

@mdmorgan is following 20 prominent accounts