Sophie Claudel, MD

Great summary!

Thank you!

I’m extremely honored to have been chosen as one of this year’s STAT Wunderkinds and grateful for the incredible support of my mentors @ashunephro.bsky.social and Sus Waikar!! @bu_bmc_renal 🎉 #nephsky

www.statnews.com/wunderkinds/

Visual abstract from Jade Teakell

Design of the CURE study which we hope will disentangle the etiologies and mechanisms of CKDu (beyond mesoamerican nephropathy - there’s one site in India too, though not Sri Lanka ) www.kireports.org/article/S246... in @kireports.bsky.social
#NephSky

Urinary Albumin-to-Creatinine Ratio, Serum Potassium Level, Estimated Glomerular Filtration Rate, and Systolic Blood Pressure over Time.

The first #ERA25 simultaneous pub

CONFIDENCE trial of empagliflozin + finerenone in N = 579

Greater reduction in ACR and BP
Note the impressive GFR dip

www.nejm.org/doi/full/10....

Cardiovascular mortality increases with stage of cardiovascular–kidney–metabolic syndrome Nature Reviews Nephrology, Published online: 31 March 2025; doi:10.1038/s41581-025-00957-yCardiovascular mortality increases with stage of cardiovascular–kidney–metabolic syndrome

ICYMI:

Thank you @asnkidney.bsky.social for highlighting our work!

@ashunephro.bsky.social

Learned quite a lot about interactions, thresholds, and synergistic effects from @ashunephro.bsky.social in this analysis of albuminuria, heart failure, and CKD progression. Our findings emphasize albuminuria as a key biomarker for CKM health. 🫘
@jaccjournals.bsky.social #NephSky

Thank you @danieljdrucker.bsky.social !!

Extremely grateful to @ahascience.bsky.social and @ashunephro.bsky.social for the opportunity to publish this comprehensive review on albuminuria in #Circulation. We cover albuminuria in the spectrum of #CKM disorders. Please take a look!
@nephjc.bsky.social #NephSky

Thank you! And yes, I completely agree.

Very proud of our #BMCimRes internal medicine residents for coming up with this project idea and seeing it through to publication! We looked at current statin prescribing practices for young adults in the US and their CVD risk.

authors.elsevier.com/a/1khiu2gOwG...

Excited to share this research letter looking at albuminuria values in healthy adults! We followed IFCC guidelines for establishing references ranges, which had not previously been shown in the literature, and consider what “normal” should be by sex.

Very proud of this project that started as a casual conversation on #CKM syndrome with @ashunephro.bsky.social over a year ago and is now in print at #JASN! Couldn’t have done it without @ashunephro.bsky.social teaching me about cumulative incidence curves in #NHANES.

Cumulative Incidence of Mortality Associated with... : Journal of the American Society of Nephrology e corresponding restricted mean survival time over a 15-year period. Methods: This is a longitudinal study of 50,678 community-dwelling U.S. adults aged 20 and older with baseline data for CKM stag...

Thrilled to share our publication led by exceptional @sophieclaudel.bsky.social "Cumulative Incidence of Mortality Associated with Cardiovascular-Kidney-Metabolic Syndrome" in @asnpublications.bsky.social journals.lww.com/jasn/abstrac... @asnkidney.bsky.social @americanheart.bsky.social

DOT’s Plan to Distribute Funding by Birth and Marriage Rates Would Leave Communities Most In Need Behind If enacted, the new US Department of Transportation memo would prioritize funding to whiter, higher-income, more car-dependent areas over communities of color and people who walk, bike, or take public...

The US DOT says it's planning to prioritize areas with high marriage & high birth rates for funding.

Our new analysis @urbaninstitute.bsky.social shows this would disproportionately fund:
—Communities with a higher white resident share
—Low-density areas
—High-income areas
—Car-dependent areas

Hyperaldosteronism in CKD (and CVD) is something I’ve been trying to learn more about recently. Hoping to join tonight! #nephjc

Very proud of this work! Thanks to @ashunephro.bsky.social and co-mentors for their support of this project

Social Determinants of Health and Cumulative Incidence of Mortality Among US Adults Without Major Chronic Diseases - Journal of General Internal Medicine Background Social determinants of health (SDOH) are associated with poor health outcomes among individuals with prevalent diseases. Objective To quantify the association between adverse SDOH and morta...

Very excited to share this work by my mentor Dr. Ashish Verma and me on #SDOH and #mortality among adults *without* major chronic diseases published in @JGIM! We looked at food insecurity, employment, income, acculturation, education and healthcare access.

link.springer.com/article/10.1...

The post-Thanksgiving consult bolus is real… 🧂

Sophie, enjoying life as a renal fellow in Boston. No COI #NephJC

NHANES 2021-2023 was recently released, but big changes in sampling methodology. And labs released so far don’t include a BMP or UACR! Hopefully soon?? HTN and DM prevalence pubs are out from CDC.

You are too kind, Tony!! I’m excited to be a part of the #medsky community. Kidney content coming soon! 🫘