Alix Lee

Researchers at @lshtm.bsky.social, led by @josebengoechea.bsky.social, will conduct a £2.2M study funded by UK MRC to investigate how Klebsiella pneumoniae silently colonises the gut before causing deadly infections. 🔬🦠

Read more 👉 bit.ly/4mNSreh

Check out our new #MSc in Biomedical and Clinical Research.

Acquire a broad skill set, selecting a biomedical or clinical focus. Join a vibrant, multi-national community with cutting-edge research projects in #infection & #immunobiology, #AMR, #respiratory #medicine, and more.

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Using AI-driven computer vision and high-throughput multiplexed human cell infection assays to dissect intra- and intercellular signalling networks and discover new antimicrobials at Queen’s Universit... PhD Project - Using AI-driven computer vision and high-throughput multiplexed human cell infection assays to dissect intra- and intercellular signalling networks and discover new antimicrobials at Que...

Funded 4-year #PhD in the exciting BBSRC NILAB program. @wwiem-qub.bsky.social

Receive multidisciplinary training, develop #infection models and #AI image analysis to reveal bacterial & viral disease mechanisms & discover new antimicrobials. Fight #AMR

Get in touch!
Details: tinyurl.com/e5k6ptua

Klebsiella pneumoniae disrupts vasodilation by targeting eNOS post translational modifications via the type VI secretion system and the capsule polysaccharide Vasodilation is a crucial protective response to inflammation and infection. Endothelial cells control vasodilation through the bioavailability of eNOS-produced nitric oxide (NO), and the generation o...

New pre print! We establish an ex vivo blood vessel model to investigate the effect of infection on vascular physiology in real time. We show Klebsiella inhibits vasodilation in a T6SS-dependent manner by targeting eNOs. Superb work by @safimicro.bsky.social www.biorxiv.org/content/10.1...

Klebsiella pneumoniae emerging anti-immunology paradigms: from stealth to evasion Klebsiella pneumoniae (KP) is a global threat to human health due to the isolation of multidrug-resistant strains. Despite advancements in understanding KP’s population structure, antibiotic resistanc...

🔊Online now: Klebsiella pneumoniae emerging anti-immunology paradigms: from stealth to evasion

Review by José Bengoechea (@josebengoechea.bsky.social) & colleagues

OA link: www.cell.com/trends/micro...

Klebsiella pneumoniae emerging anti-immunology paradigms: from stealth to evasion Klebsiella pneumoniae (KP) is a global threat to human health due to the isolation of multidrug-resistant strains. Despite advancements in understandi…

Last work from the lab in @cp-trendsmicrobiol.bsky.social !
We review the most recent evidence on the strategies deployed by Klebsiella to counteract host defences. www.sciencedirect.com/science/arti... The co-evolution with the immune system has taught the bug a couple of tricks!!!

@dralixlee.bsky.social