FABULOUS ๐
10.12.2025 22:47 โ ๐ 3 ๐ 1 ๐ฌ 0 ๐ 0@jacobphd.bsky.social
Scientist errant. Genetics, evolution, whimsy, awe. https://connects.catalyst.harvard.edu/Profiles/display/Person/173289 ๐งฌ๐ฆ๐๐ฉธ๐ค๐ฆ ๐๐ธ๐งฌ
FABULOUS ๐
10.12.2025 22:47 โ ๐ 3 ๐ 1 ๐ฌ 0 ๐ 0My new favorite Bsky account
10.12.2025 08:18 โ ๐ 1 ๐ 1 ๐ฌ 0 ๐ 0Biolojical is on Bluesky! Share some emoji-based science!
@jfmclaughlin92.bsky.social
@c0nc0rdance.bsky.social
@stairwaytokevin.bsky.social
@whysharksmatter.bsky.social
@sarahmackattack.bsky.social
@edyong209.bsky.social
@carlbergstrom.com
@jopabinia.bsky.social
@carlzimmer.com
@tetzoo.bsky.social
Biolojical is now on BlueSky!
(not promising anything new, but moved some of my favorite posts over from the other site)
Species:
๐ฆ
Genus:
๐ฆ๐ฏ
Family:
๐ฆ๐ฏ๐ฑ
Order:
๐ฆ๐ฏ๐ฑ๐ป
Class:
๐ฆ๐ฏ๐ฑ๐ป๐จ
Phylum:
๐ฆ๐ฏ๐ฑ๐ป๐จ๐ธ
Kingdom:
๐ฆ๐ฏ๐ฑ๐ป๐จ๐ธ๐ฆ
Domain:
๐ฆ๐ฏ๐ฑ๐ป๐จ๐ธ๐ฆ
๐
๐๐ถ๏ธ๐ ๐๐๐ฒ
Kingdom:
๐
๐๐ถ๏ธ๐ ๐๐๐ฒ
Phylum:
๐
๐๐ถ๏ธ๐ ๐๐
Class:
๐
๐๐ถ๏ธ๐ ๐
Order:
๐
๐๐ถ๏ธ๐
Family:
๐
๐๐ถ๏ธ
Genus:
๐
๐
Species:
๐
ยฐLatitude:
90โ๏ธ
80๐บ
70๐บ๐ป
60๐บ๐ป๐๐ฟ
50๐บ๐ป๐๐ฟ
40๐บ๐ป๐๐ฟ๐ต๐ฏ
30๐บ๐ป๐๐ฟ๐ต๐ฏ๐ฆ๐๐๐ช๐ฆ๐ผ
20๐บ๐๐ฟ๐ต๐ฏ๐ฆ๐๐๐ช๐ฆ
10๐บ๐๐ฆ๐ต๐ฏ๐ฆ๐๐๐ช๐ฆ๐ฆ
0๐ง๐ฆ๐๐ฆ๐ต๐ฏ๐ฆ๐๐๐ช๐ฆ๐ฆ
10๐ง๐ฆ๐๐ฆ๐ต๐ฏ๐ฆ๐๐๐ฆ
20๐ง๐ฆ๐๐ฆ๐ต๐ฆ๐ฆ๐๐๐ฆ๐จ
30๐ง๐ฆ๐๐ฆ๐ต๐ฆ๐ฆ๐๐๐ฆ๐จ
40๐ง๐ฆ๐๐ฆ๐ฆ
50๐ง๐ฆ๐ฆ
60๐ง
70๐ง
80๐ง
90โ๏ธ
Who shares a common ancestor with you __ million years ago?
2โฐ๐ฉ๐ฝ
2ยน๐ฉ๐ฝ
2ยฒ๐ฉ๐ฝ
2ยณ๐ฉ๐ฝ๐ฆ
2โด๐ฉ๐ฝ๐ฆ
2โต๐ฉ๐ฝ๐ฆ๐
2โถ๐ฉ๐ฝ๐ฆ๐
2โท๐ฉ๐ฝ๐ฆ๐๐ฎ๐ฆ
2โธ๐ฉ๐ฝ๐ฆ๐๐ฎ๐ฆ๐จ๐ฆ
2โน๐ฉ๐ฝ๐ฆ๐๐ฎ๐ฆ๐จ๐ฆ๐ฆ๐
2ยนโฐ๐ฉ๐ฝ๐ฆ๐๐ฎ๐ฆ๐จ๐ฆ๐ฆ๐ ๐๐ฆ
2ยนยน๐ฉ๐ฝ๐ฆ๐๐ฎ๐ฆ๐จ๐ฆ๐ฆ๐ ๐๐ฆ๐๐ณ
2ยนยฒ๐
"The great Tree of Lifeโฆ with its ever-branching and beautiful ramifications"
-C Darwin
โโโ๐ฏ๐ผ๐บ๐ท๐ณ๐ฆ
โ โ|
โ| โ๐๐ฆ๐ง๐ฐ๐ฟ๏ธ๐น
| |
โ| โ๐๐ฆ๐ง๐ฆ
๐๐ข
| |
| โ๐ท๏ธ๐ฆ๐ฆ๐๐ฆ๐
|
| โ๐ท๐พ๐ฝ๐๐๐ฅฅ
| |
โ| โ๐ต๐ฅ๐ฅ๐ป๐ถ๏ธ๐ฅ
| |
โ| โ๐๐ฅ๐น๐๐๐
โ โ|
โโโ๐๐๐๐ฅฆ๐ซ๐บ
Calendar of evolution:
Jan 1โฃ1st life
Nov 2๐1st animals
Nov 20๐1st land animals
Nov 23๐ฆ1st sharks
Nov 26๐ธ1st tetrapods
Dec 3๐ฒ1st seed plants
Dec 9๐๐
Dec 10๐ฆ1st dinos
Dec 11๐ญ1st mammals
Dec 19๐ผ1st flowers
Dec 20๐ฆ1st birds
Dec 25๐ฆ1st T rex
Dec 26โ๐
Dec 31๐1st humans
The 5 evolutionary mechanisms:
Mutation
๐บ๐บ๐บ๐บโโข๏ธ๐บโ๐บ๐บ๐บ๐
Selection
๐บ๐บ๐บ๐โ๐ง๐ฟโฅ๏ธ๐โ๐๐๐๐
Gene flow
๐๐๐๐โ๐ถ๐ฉโ๐๐ฉ๐๐
Drift
๐๐ฉ๐๐โ๐ช๏ธโ๐ฉ๐ฉ๐๐
Non-random mating
๐ฉร๐,๐ซ๐ร๐โ๐ฉ๐ฉ๐ฉ๐ฉ
The Scientific Method:
Question
โ๐ฑ=โ
Hypothesis
โ๐ฑ=โต๏ธ
Experiment
โ๐ฑ+๐
Result
โ๐ต
Conclusion
โ๐ฑโ โต๏ธ
What evolution means for youโก๏ธ
1. Weโre all one big familyโ โshare theโค๏ธ:
โ๐ป๐ณ๐ฆ๐ฆ๐ข๐
2. A continuous๐of variation is natural in a species:
โ๐ง๐ผโ๐ง๐ฟ
โโ๏ธโโ๏ธ
โ๐ฌโ๐ซ
โโฆ& everything in betweenโฆ
3. You werenโt created to fill a role, but๐to be anything:
โ๐ท๐ฝโโ๏ธ๐จโโ๏ธ๐จ๐ปโ๐ค๐ฉ๐ผโ๐๐จ๐พโ๐๐ฉ๐ฟโ๐ญ
If๐บcame from๐why do we still have๐?
If๐บ๐ธcame from๐ฌ๐งwhy do we still have๐ฌ๐ง?
If๐came fromโฝ๏ธwhy do we still haveโฝ๏ธ?
If๐คcame fromโต๏ธwhy do we still haveโต๏ธ?
Ifโ๏ธcame fromโก๏ธwhy do we still haveโก๏ธ?
If๐กcame from๐ฏ๏ธwhy do we still have๐ฏ๏ธ?
If๐ฅจcame from๐why do we still have๐?
Precambrian:
๐ฆ
๐ฆ
๐ฆ
๐ฆ
Paleozoic:
๐ฆ ๐
๐ฆ ๐๐ฑ
๐ฆ ๐๐ฑ๐ฆ
๐ฆ ๐๐ฑ๐ฆ๐ฆ
Mesozoic:
๐ฆ ๐๐ฑ๐ฆ๐ฆ๐
๐ฆ ๐๐ฑ๐ฆ๐ฆ๐๐ญ
๐ฆ ๐๐ฑ๐ฆ๐ฆ๐๐ญ๐ผ
๐ฆ ๐๐ฑ๐ฆ๐ฆ๐๐ญ๐ผ๐ฆ
Cenozoic:
๐ฆ ๐๐ฑ๐ฆ๐ฆ๐๐ญ๐ผ๐ฆ๐
๐ฆ ๐๐ฑ๐ฆ๐ฆ๐๐ญ๐ผ๐ฆ๐๐
๐ฆ ๐๐ฑ๐ฆ๐ฆ๐๐ญ๐ผ๐ฆ๐๐๐
๐ฆ ๐๐ฑ๐ฆ๐ฆ๐๐ญ๐ผ๐ฆ๐๐๐๐ถ๐พ
DNA translation:
dogcabcandewegg โ ๐๐๐ฅซ๐ง๐ฅ
Missense mutation:
dogcabmandewegg โ ๐๐๐ด๏ธ๐ง๐ฅ
Synonymous mutation:
dogcarmandewegg โ ๐๐๐ด๏ธ๐ง๐ฅ
Frameshift mutation:
dogcodarmandewegg โ ๐๐๐ช๐ฝ&๐
Nonsense mutation:
dogcodarmendewegg โ ๐๐๐ช๐ฝ๐
Where science happens:
๐ญin vivo
๐งชin vitro
๐๏ธin situ
๐คฐin utero
๐ฅin ovo
๐ฅ๏ธin silico
๐ง in cerebro
๐ปin stereo
๐in silencio
๐ฅผin vestimento
๐in indusia
๐๏ธin institutione
๐กin domo
๐ณin saltu
๐ฉ๐ฟโ๐ฌ๐จ๐ผโ๐ฌ๐ฉ๐ฝโ๐ฌ๐ฉ๐ปโ๐ฌ๐จ๐พโ๐ฌin omnio
Chromosome #
2๐
6๐ฆ
14๐ฅ
16๐จ๐๐
18๐๐ฅ๐ฅฆ๐ฅฌ
20๐ฆ๐ฝ
22๐ฆ๐
24๐ท๐ถ๏ธ๐ฅ๐
26๐
28๐น
30๐ฆ
32๐๐๐ฅฅ
33๐
34๐ฆ๐๐๐ป
36๐๐ฆ
38๐ฆ๐ฆ๐ท๐
40๐ญ๐ฅ๐ฅญ
42๐ผ๐๐ก
44๐ฌ๐น๐ฐ๐ฆก
46๐ฅ๐ฆ
48๐ฆ๐ฅ
50๐๐
54๐
56๐๐
60๐ฎ๐
64๐ด
66๐ฆ
๐ฆ
70๐ฆ
74๐ป๐ช๐ฆ
76๐๏ธ
78๐๐ถ๐บ
80๐ฆ๐ฆ๐ฆข
82๐ฆ๐ฆ
84๐บ
88๐ฆ
90๐
110๐ฆ
174๐ฅ
Biolojical is now on BlueSky!
(not promising anything new, but moved some of my favorite posts over from the other site)
Listen, I want a cute pet raccoon as much as the next person (ok I don't, you don't want to live a life with a chaos gremlin with HANDS).
But if you've seen the paper about how raccoons are on their way to domestication... brookshire-team-trash.beehiiv.com/p/raccoons-d...
I wanted to use this framework to talk about how we should and shouldn't think about genetic diversity and how it evolves. Plus these are just amazing histories of two charismatic species, if I do say so myself.
Check it out:
adaptivediversity.wordpress.com/2025/12/04/b...
Cover of Hedrick population genetics textbook featuring multicolored wovles
Plate from an old biology book that gives a false picture of sharp differences among human races
Wolf coat color is an iconic case study in pop gen, but the whole wild story โ that it comes from domestic dogs via an antimicrobial peptide gene โ isn't widely known. And the parallels with human color polymorphism โ both the truth and our ugly misperceptions of it โ are striking.
05.12.2025 19:08 โ ๐ 2 ๐ 0 ๐ฌ 1 ๐ 1Black and White and Read All Over: pigment evolution in humans and wolves, and our oft-misguided perceptions of genetic variation
adaptivediversity.wordpress.com/2025/12/04/b...
Cows, sheep, and goats are cladistically antelopes. I often hear how chicken nuggets are dinosaur meat, but rarely about the ubiquity of antelope burgers.
04.12.2025 00:50 โ ๐ 3 ๐ 0 ๐ฌ 0 ๐ 0Herb Robert aka Stinky Bob
Please, Herb Robert was my father. Call me Stinky Bob.
03.12.2025 17:39 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0Cookie Monster doing his thing
Cookie Monster is a good model of a catabolic enzyme.
โขspecific substrate
โขglobular shape
โขdoes not remove anything, but simply breaks large reactants into smaller products
โขnotable release of energy
His-Ala-Pro-Pro-Tyr
Thr-His-Ala-Asn-Lys-Ser-Gly-Ile-Val-Ile-Asn-Gly
Conversation in my mentions about homology between heme and chlorophyll
26.11.2025 00:06 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0tetrapyrrole biosynthetic pathway from https://pmc.ncbi.nlm.nih.gov/articles/PMC2883787/
They did not arise independently. They are both synthesized from protoporphyrin IX, sometimes in the same organism. However, there is no evidence that our microbial ancestors were ever photosynthetic. Plants have heme, but animals do not have chlorophyll. So heme probably came first.
25.11.2025 23:20 โ ๐ 1 ๐ 1 ๐ฌ 1 ๐ 1Frankensteinโs monster, having hidden immortal in the Arctic for 200 years, learns of modern biotechnology and re-enters civilization seeking a path to true humanity. But neither reactionary prejudice nor scientific hubris has changed much in two centuries.
Why isnโt this a movie or graphic novel?
A painful truth all dads must learn: if you wear a baseball cap while running around on playground equipment designed for children, the brim will block your upper view and you will bonk your head.
24.11.2025 02:05 โ ๐ 5 ๐ 3 ๐ฌ 0 ๐ 0