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Kritarth Singh

@kritsh.bsky.social

Cell biologist, Research fellow at UCL, Duchen Lab | Studies mitochondrial biology in neurodegenerative diseases ๐Ÿง ๐Ÿ”ฌ

11 Followers  |  17 Following  |  3 Posts  |  Joined: 03.06.2025  |  1.7166

Latest posts by kritsh.bsky.social on Bluesky

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Redox-dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells When probed using fluorescence lifetime imaging microscopy (FLIM), the emission from reduced nicotinamide adenine dinucleotide (NADH) and its phosphorylated form NADPH have shown promise as sensitive ...

www.biorxiv.org/content/10.1...

14.07.2025 13:43 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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the โ€˜rightโ€™ balanceโ€ฆ๐Ÿค”
(Yanai & Lercher, 2025)

06.06.2025 18:46 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Pathogenic variants in autophagy-tethering factor EPG5 drive neurodegeneration through mitochondrial dysfunction and innate immune activation The autophagy-tethering factor, ectopic P-granule 5 autophagy protein (EPG5), plays a key role in autophagosome-lysosome fusion. Impaired autophagy associated with pathogenic variants in EPG5 cause a ...

Our latest preprint!

03.06.2025 21:01 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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