Q-Lab

Thanks Alex!! Totally mutual!! Your work on epigenetic evolution is really inspiring!

Thanks Pierre!!

Thanks Vincent!!

Thanks Anne!!

Thanks Max!!!

📢The project will start in Summer 2026 and we will be recruiting postdocs interested in TE–host relationships, protein evolution and AI-powered genomics. If this resonates, feel free to reach out! More details soon.

🙏 Huge thanks to everyone who read drafts, challenged ideas, shared feedback and kept spirits up during the writing and interview stages, and to my team for their hard work, discussions and constant enthusiasm that pushed this proposal forward!!

💡With HosTEome, we will chart TE–host relationships across the eukaryotic tree of life, follow their coevolution, and ask how cellular context and specific molecular partnerships shape whether a TE invasion can take hold and persist, or instead is contained and eventually goes extinct.

🧬TEs are some of the most successful genetic invaders, reshaping chromosomes, rewiring gene regulation and sometimes contributing to adaptation and disease. A central question is when a genome becomes a “welcoming” environment for these elements, and how that changes across the tree of life.

🎉 Very grateful and proud to share that I have been awarded an #ERCCoG to support our research on transposable elements!!! @erc.europa.eu @cnrs.fr @cnrsbiologie.bsky.social @parissaclay.bsky.social @ips2parissaclay.bsky.social

Transposable elements are vectors of recurrent transgenerational epigenetic inheritance DNA methylation loss at transposable elements (TEs) can affect neighboring genes and be epigenetically inherited in plants, yet the determinants and significance of this additional system of inheritan...

Happy to share the results of a long-haul post-doc project, now online @science.org, aiming at understanding the rules of transgeneration epigenetic inheritance over TEs in plants and its extent and impact in nature. More below!
doi.org/10.1126/scie...

An RNA Splicing System that Excises Transposons from Animal mRNAs All genomes harbor mobile genetic parasites called transposable elements (TEs). Here we describe a system, which we term SOS splicing, that protects C. elegans and human genes from DNA transposon-medi...

Cool story - SOS splicing to remove transposons in mRNA! Though not by the spliceosome.

www.biorxiv.org/content/10.1...

Drosophila Genetic Database The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @camplantsci.bsky.social
www.jobs.cam.ac.uk/job/51488/

Our preprint has now found a wonderful home in @molbioevol.bsky.social. Shout out to our collaborators in the Mozgova lab too 💚

See you at Jussieu in Paris tomorrow at 1:30 PM! We will march by the Statue of Liberty at Luxembourg Garden, a great symbol of our treasured alliance and shared values! 🧪🗽 @standupforscifr.bsky.social @sufs-paris-rp.bsky.social @standupforscience.bsky.social

When your kids ask you what you did to save US science in the crisis of ‘25, you will say that you showed up! Please spread the word and join us!!
@standupforscience.bsky.social

Diagram of somatic TE insertions across the A. thaliana genome

In our latest @biorxiv-genomic.bsky.social preprint, we describe our approach to use PacBio HiFi reads to detect somatic TE transposition -- good enough to detect rare events that are present in only single cells. Led by Andrea Movilli.
#plantscience
www.biorxiv.org/content/10.1...

CRISPR targeting of H3K4me3 activates gene expression and unlocks centromeric crossover recombination in Arabidopsis H3K4me3 is a fundamental and highly conserved chromatin mark across eukaryotes, playing a central role in many genome-related processes, including transcription, maintenance of cell identity, DNA dama...

Very nice new paper from my neighbours www.biorxiv.org/content/10.1...

Long-read detection of transposable element mobilization in the soma of hypomethylated Arabidopsis thaliana individuals https://www.biorxiv.org/content/10.1101/2025.02.07.637047v1

Have protein-ligand co-folding methods moved beyond memorisation? Deep learning has driven major breakthroughs in protein structure prediction, however the next critical advance is accurately predicting how proteins interact with other molecules, especially small mo...

Excited to share our latest preprint evaluating AlphaFold3, Boltz-1, Chai-1 and Protenix for predicting protein-ligand interactions, featuring our newly introduced benchmark dataset 🌹Runs N’ Poses🌹!

www.biorxiv.org/content/10.1...

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📣 #EMBOMobileGenome is open for registrations!

Assembling experts in genomics, epigenetics, structural biology, evolutionary biology, and developmental biology to discuss the broad impact of TEs on organismal biology. 🧬🔍

📜 Submit abstract by 29 July!
👉🏼 https://s.embl.org/mge25-01-bl

The mobile genome: genetic and physiological impacts of transposable elements

Dear all, registrations are open for the Mobile Genome @EMBO workshop. Many slots for posters, short talks but also long talks for last minute groundbreaking results! Let’s meet again on Nov 4-7, 2025 in Heidelberg. www.embl.org/about/info/c...

You have plenty of time to send us your abstracts, but please block the dates in your calendar already! Looking forward to welcoming you in Heidelberg!! #EMBOMobileGenome! @events.embl.org

A sit-in Monday Jan 27th 16h30 will happen in front of the College de France in protest against the government cuts to higher education and research.

Congratulations Angélique! Very cool work!! 👏

Congratulations Sole!!!

Double trouble: two retrotransposons triggered a cascade of invasions in Drosophila species within the last 50 years - Nature Communications Horizontal transfer of genetic material in eukaryotes has rarely been documented over short evolutionary timescales. Here, the authors show that two transposable elements, Shellder and Spoink, invaded...

super proud - our new work about the invasions triggered by two troublesome TEs in Nat. Comm. www.nature.com/articles/s41...

The Institute for Integrative Biology of the Cell (I2BC) is seeking to recruit new group leaders to join the Virology Department.
The application deadline is March 15th, 2025
www.i2bc.paris-saclay.fr
www.i2bc.paris-saclay.fr/wp-content/uploads/2025/01/I2BC-Virology-call_2025.pdf

Director, Institute for Quantitative and Computational Biosciences University of California, Los Angeles is hiring. Apply now!

My division at UCLA is recruiting a new Director for our Institute for Quantitative and Computational Biosciences. We're a fun cross-departmental community focused on quantitative biology education and research. Consider applying!

recruit.apo.ucla.edu/JPF10007