Simone Papa

Most comprehensive review of DBS in epilepsy to date (124 studies, 1,210 patients, and 20 anatomical targets) 😱
www.medrxiv.org/content/10.1...

Online Hate Speech Resembles Mental Health Disorder Language - Neuroscience News A new study using AI tools found that posts in online hate speech communities closely resemble the speech patterns seen in forums for certain personality disorders.

AI analysis finds online hate speech posts mirror the language seen in communities for borderline, narcissistic, and antisocial personality disorders, raising questions about how online toxicity may shape behavior over time.

neurosciencenews.com/online-hate-...

On this day 100 years ago physics laureate Werner Heisenberg submitted a paper that revolutionised quantum mechanics.

Heisenberg was only 23 years old when he submitted the paper.

He was awarded the Nobel Prize in Physics for 1932.
(By TheNobelPrize)

www.nobelprize.org/prizes/physi...

“I have come to think that physics is a never ending quest.”
Isaac Isidor Rabi discovered a method to measure the magnetic properties of atomic nuclei, research that would later be used for MRI and atomic clocks.
He was awarded the Nobel Prize in Physics 1944.
www.nobelprize.org/prizes/physi...

Designing and testing #biomimetic #neurostimulation of PNS to restore #somatosensation in #bionic limbs 🦿
Paper: www.nature.com/articles/s41...
Video: m.youtube.com/watch?si=CDB...

#neuroscience #neuroprosthetics Eidgenössische Technische Hochschule Zürich Nature Portfolio

A 2024 #ScienceAdvances analysis involving data from more than 35,000 adults with dyslexia has revealed structural differences in the brain that correlate with a genetic predisposition to dyslexia.
(by ScienceMagazine)
Learn more on #WorldBrainDay: scim.ag/4kOM4oQ

The optimistic brain: scans reveal thought patterns shared by positive thinkers Insights from brain imaging could have implications for mental-health research.

Optimistic people share patterns of brain activity, and make more of a distinction between positive and negative events than pessimists do.
www.nature.com/articles/d41...

YouTube video by Mathis Laboratory for Adaptive Intelligence CellSeg3D Demo on Mouse Brain Tissue

Self-supervised, label-free 3D cell imaging is here

EPFL researchers introduce CellSeg3D, a self-supervised tool for 3D cell segmentation in fluorescence microscopy, eliminating the need for manual labeling and enhancing accessibility for various biological studies.
youtu.be/3UOvvpKxEAo

Neurons on fire 🔥
Check how these microglia ( 🟡 Iba1) interact with neurons ( 🔵 map2), accumulating phospho-Tau ( 🔴 at8).
What is happening there?
Are these microglia making things better or worse?
(By Danielle Beckman, Ph.D)
#Neuroinflammation #Microscopy #Neuroscience

Einstein, Curie, Bohr, Planck, Heisenberg, Schrödinger… how many Nobel Prize laureates can you spot? (By The Nobel Prize)

Photo: Benjamin Couprie, Institut International de Physique Solvay, Leopold Park, Brussels, Belgium. Public domain via Wikimedia Commons.
#NobelPrize

The researchers identified an early, previously unrecognized vulnerability in Alzheimer's disease that affects the deep cortical layers (layers 5/6) www.cell.com/neuron/fullt... #Brain #TheCell #Neuron

Last year in Science, researchers generated a nanoscale-resolution reconstruction of a millimeter-scale fragment of human cerebral cortex (By Science Magazine)
www.science.org/doi/10.1126/...

#WorldBrainDay #Cortex

Researchers used a mouse model to gain insights into how exercise alters brain cells to protect them against Alzheimer’s disease. The findings hint at possible future treatment strategies. bit.ly/3Ig77Dm
(byThe National Institutes of Health)

DELIVR, a user-friendly deep-learning pipeline for automatically detecting and analyzing cells from whole-brain images to map neuronal activity via cFOS
(by Ali Maximilian Ertürk, CEO of Deep Piction)
www.nature.com/articles/s41...
#neuroscience #cFOS #brain

🧠 An Overview of Brain Technologies
This stunning visual “The BCI Universe” maps out the expanding landscape of brain-computer interface (BCI) technologies, from noninvasive sensing tools like EEG and fMRI to invasive neural implants like DBS (by Nicolas Hubacz, M.S).
Credit: BrainMind

From robotic to real?
We are entering a new era of mind-controlled limbs. Neuroprosthetic limbs are no longer science fiction, they are rapidly transforming into natural extensions of the human body (by Michael S Okun)
onlinelibrary.wiley.com/doi/10.1002/...
#neuroscience #neuroprosthetic

A 3D Look at Brain Connectivity 🧠
This colorful 3D reconstruction comes from a type of MRI scan called diffusion tensor imaging (DTI)
🔴 Red - fibers running left to right
🔵 Blue - top to bottom
🟢 Green - front to back
(by Nicolas Hubacz, M.S.)
Credit to USC for the video
#Connectivity #Brain

In Russia, a unique statue pays tribute to lab mice that sacrificed their lives for scientific progress.

It's a heartfelt acknowledgment of their contribution to humanity's advancements in health and science.

#lab #mice

Amyloid-beta: Villain or Hero? What do you think?
The image below is a human brain with Alzheimer's. Staining for Amyloid-β in 🔵 and astrocytes in 🟡
(by Danielle Beckman, Ph.D)
#neuroscience #Amyloid #Alzheimer's

Embryos of the American Alligator
The American alligator is found throughout the Southeastern United States. Females build nests for their eggs and care for the eggs and young hatchlings. Sex determination is temperature dependent.

Credit: Davalyn Powell, PhD from the Embryology
#nature #embryology

Dorothy Crowfoot Hodgkin
"I should not like to leave an impression that all structural problems can be settled by X-ray analysis or that all crystal structures are easy to solve. I seem to have spent much more of my life not solving structures than solving them."

www.nobelprize.org/stories/wome...

A new suite of harmless viruses allows researchers to target almost any type of brain cell (Allen Institute)

Review by Holly Barker for The Transmitter: www.thetransmitter.org/cell-types/e...
🎥: Tanya Daigle, Emily Kussick, LifeCanvas Technologies Inc.
#neuroscience

www.nature.com/nataging/vol...
Sarah Hoelzl et al. Technical University of Munich 🎉
The cover depicts the Three Fates, who manipulate the threads of life and death. The Fates are shown as three older women, unraveling the threads of the inactive X chromosome during aging.
#nature #chromosome

🧠 T.S. Binns work is now published in Nature Communications: www.nature.com/articles/s41...

Their findings pave the way for next-generation adaptive DBS, where machine learning can decode real-time network states to guide stimulation, not just locally, but across brain-wide circuits.
#neuroscience

A striking 3D visualization showing neuron distribution across the entire mouse brain (color-coded by anatomical region) from our new brain atlas initiative derived form precisely aligned Nissl-stained slices (by Sebastien Piluso)
direct.mit.edu/imag/article...

Facial Expressions Reveal Hidden Cognitive States - Neuroscience News New research shows that facial expressions can reveal internal cognitive states, accurately predicting task performance across both macaques and mice.

Facial Expressions Reveal Hidden Cognitive States

Facial expressions don't just show emotion, they reveal how we think.individuals.
neurosciencenews.com/facial-expre...
#neuroscience #facialexpressions #cognitive

𝗪𝗵𝗮𝘁 𝗶𝗳 𝘄𝗲 𝗰𝗼𝘂𝗹𝗱 𝗺𝗮𝗽 𝗰𝗿𝗲𝗮𝘁𝗶𝘃𝗶𝘁𝘆 𝘁𝗼 𝗮 𝘀𝗽𝗲𝗰𝗶𝗳𝗶𝗰 𝗰𝗶𝗿𝗰𝘂𝗶𝘁 𝗶𝗻 𝗼𝘂𝗿 𝗯𝗿𝗮𝗶𝗻?
Study by researchers at Harvard Medical School in which the authors analysed functional magnetic resonance imaging data of over 800 individuals performing #creativity tasks (by Christian Tidona)
jamanetwork.com/journals/jam...

🧠 Connections between Hippocampal Neurons

Confocal microscopy image of neurons cultured from hippocampi of newly born mice at 63x magnification (by Igor Korolev, DO, PhD)

(IMAGE CREDIT: Jason Kirk, Quynh Nguyen; Baylor College of Medicine)
#neurons #Hippocampal #neuroscience

AI applied in microscopy photo 😱 What do you think?"
(by Danielle Beckman, Ph.D.)
#NeuroArt #SciArt #Neuroscience #Neuron

This fiery mixture of red and green neurons in the brain of a mouse shows how interconnected different types of neurons in the brain can be. Green:excitatory pyramidal neurons Red: inhibitory interneurons (Hippocampus of a mouse)
Credit: Nelson Spruston and Erik Bloss, HHMI's Janelia Research Campus