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AndexerLab

@andexerlab.bsky.social

Interested in cofactor-dependent enzymes, cofactor analogues and cofactor regeneration systems. https://www.pharmazeutische-chemie.uni-freiburg.de/de/andexer

47 Followers  |  39 Following  |  3 Posts  |  Joined: 06.12.2024  |  1.6027

Latest posts by andexerlab.bsky.social on Bluesky


Thanks to all co-workers, this was a great team effort and an important part in the preparation process of @for5596.bsky.social - now happy to see the ChemBioChem view statistics.

17.04.2025 08:52 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
How to Tell an N from an O: Controlling the Chemoselectivity of Methyltransferases S-Adenosyl-l-methionine (SAM)-dependent methyltransferases (MTs) are important enzymes in numerous biological pathways. They share a common SN2 mechanism but act on different nucleophilic substrates i...

If you want to know how to tell an N from an O, you can get some ideas in our new paper. This was a great team effort, introducing us to new methods: MD w/ Ferran Feixas & Marc Garcia Borrร s (Girona) + HDX-MS w/ Wieland Steinchen & Gert Bange @bangebalcony.bsky.social
pubs.acs.org/doi/10.1021/...

04.04.2025 15:36 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
logo of research group FOR 5596 on SAM-dependent enzyme chemistry showing the chemical structure of S-adenosylmethionine

logo of research group FOR 5596 on SAM-dependent enzyme chemistry showing the chemical structure of S-adenosylmethionine

FOR 5596 is now on BlueSky! Follow us to stay informed about our collaborative project "Unfolding the potential of SAM-dependent enzyme chemistry".

02.04.2025 14:20 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Appell fรผr mehr Klimaschutz in den Koalitionsverhandlung

Appell fรผr mehr Klimaschutz in den Koalitionsverhandlung

Noch bis zum 24.3. Zeit den Appell fรผr mehr Klimaschutz in den Koalitionsverhandlungen zu unterschreiben.
www.bayceer.uni-bayreuth.de/s4f/de/top/o...

13.03.2025 19:32 โ€” ๐Ÿ‘ 11    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Rewiring Escherichia coli to transform formate into methyl groups - Microbial Cell Factories Background Biotechnological applications are steadily growing and have become an important tool to reinvent the synthesis of chemicals and pharmaceuticals for lower dependence on fossil resources. In ...

๐Ÿ–๏ธ We are happy to share our latest paper! Introduction of the formate assimilation from M. extorquens into E. coli allows transformation of formate into methyl groups. Renewable C1 compounds for biocatalytic methylation!
microbialcellfactories.biomedcentral.com/articles/10....

13.03.2025 15:54 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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