This is also why NIH and government-funded research is so important.
In addition to funding the entire biomedical research pipeline, it funds basic exploratory research that builds the foundation for more specific breakthroughs down the road.
Research asking questions like
'How does a lizard regulate its blood sugar when it only eats a few times a year?' (GLP-1),
'What happens when a cone snail paralyzes its prey?' (non-opioid pain medication), or 'Why are patients taking heart medication reporting unexpected erections?' (Viagra)
Again, these questions might sound aimless or even
"wasteful" at first, and they don't lead to treatments right away, which is exactly why private industry won't fund them.
So instead, government funds this research. And we all benefit from it through better treatments, longer lives, and a stronger economy.
Because every $1 invested in the NIH generates $2.56 in economic activity.
What a great ROl. Seems we should fund it more.
17.08.2025 17:33 β π 33 π 8 π¬ 0 π 0
In the 1990s, the NIH funded scientists to study the saliva of the Gila monster to understand how it regulated blood sugar between meals, since the lizard only eats a few times a year.
While studying the saliva, they discovered a peptide called exendin-4 that acts like the human hormone glucagon-like peptide-1, or GLP-1.
That discovery led to many more NIH-funded studies that eventually led to the development of the first
GLP-1 drugs used to treat type
2 diabetes.
That original exploratory research had no clear intent, and certainly wasn't
conducted with the goal of finding a treatment for type 2 diabetes. But we wouldn't have this kind of therapy today without that basic, NIH-funded research on Gila monster saliva.
This is how basic, exploratory science, without immediate application, can lay the foundation for major medical breakthroughs.
17.08.2025 17:33 β π 71 π 24 π¬ 1 π 1
the people simply clamor for a land tax
07.10.2025 17:28 β π 2 π 0 π¬ 0 π 0
once again, tostones
07.10.2025 17:18 β π 0 π 0 π¬ 0 π 0
One of the more incredible stories out of LA this year has been how a taco review blog became the best on-the-ground coverage of ICE raids in the city.
They do a dispatch every day, follow-up on the kidnapped people (which almost no media outlet has done), and fact-check government claims.
07.10.2025 04:03 β π 4371 π 1702 π¬ 18 π 35
It's not just that they're going to strike down a law against conversion therapy, it's that they're going to do it on behalf of made-up claims from a straw plaintiff who can't honestly show the law affected her at all
07.10.2025 16:06 β π 2533 π 834 π¬ 55 π 47
solange wearing yohji yamamoto
07.10.2025 15:21 β π 8 π 2 π¬ 1 π 1
The UK is within spitting distance of having more murders portrayed annually on TV shows and movies set in the country than occur in real life
07.10.2025 12:42 β π 894 π 201 π¬ 14 π 4
This picture is from 1992 in LA and using it in this post and story shows terrible news judgment.
07.10.2025 13:05 β π 2921 π 633 π¬ 70 π 27
One thing that the Swiss historically pointed to as why transit was so popular in referenda is that people who couldnβt drive (women and the elderly) are far more represented in a referendum than in a legislature or bureaucracy which tend to be filled disproportionately with able bodied men.
06.10.2025 20:26 β π 116 π 30 π¬ 2 π 4
what bill Clinton did to welfare man, that man's going straight to hell
07.10.2025 05:36 β π 1 π 0 π¬ 0 π 0
Another one added
06.10.2025 17:58 β π 177 π 26 π¬ 3 π 0
THERE ALWAYS SAYEN TALK TO YOUR DOCTOR BUT I DONT KNOW ANY ONE WHO HAS "A DOCTOR" LMAO LIKE IF THEY POP THERE BACK OUT THEY MIGHT GO TO A DOCTORS OFFICE TO BEG FOR A MRI, BUT THE DOCTOR AINT SENDING THEM CARD'S AFTERWARDS LOL ,IMAGINE IF YOU GOT "CHECK UP" WHERE YOU GO IN TO THE DOCTERS IF THERES NOTHING WRONG WITH YOU, ONE TIME I WENT TO THE DOCTERS AND THE MOTHER FUCKER OPENS UP WEB MD, LIKE I DIDENT DO THAT BEFORE I CAME IN , SO JUST SAVE US ALL SOME TIME AND LET WEB MD GIVE ME ANTIBIOTICS, IF THERS NO EFFECTIVE MEDICAL CARE FOR MOST OF THE COUNTREY THEN JUST LET ME BUY THE PILLS DIRECTLY FROM THE PILL STORE!!!!! IM TIRED OF THE LAW BINDING AND NOT PROTECTING ME!!! IF I AINT GETTING PROTECTED THEN DONT BIND MY ASS MOTHER FUCKER!!!!!!!! IF WERE DOIN THE POCALYPSE THEN LEGALIZA ALL DRUG'S AND GIVE ME THE RADIOACTIVE BEANS FROM FALL OUT!!!!! ILL EAT A DAMB GIANT ROACH IF IT MEANS I NO LONGER HAVE TO THINK ABOUT THE WORD "DEDUCTIBLE" AND DA TEXT SAYS "TALK TO YOUR DOCTOR , IM AMERICAN, I DONT HAVE A DOCTOR, WHEN I GET SICK OR HURT I GO TO A BUILDIGN THAT USE TO BE A PIZZA HUT, AND I PAY A GUY $176 TO CALL ME FAT " - DASHARE.ZONE ADMIN
TALK TO "MY DOCTOR" LOL - dashare.zone ADMIN
06.04.2025 00:04 β π 2889 π 657 π¬ 0 π 23
I love an odd little movie about people simmering in quiet desperation and the needle drops in this are insanely good
07.10.2025 02:18 β π 0 π 0 π¬ 0 π 0
99 yd pick six for Devin Lloyd, this game has flip turned up side down
07.10.2025 02:13 β π 451 π 68 π¬ 19 π 37
Dean, professor accused of denigrating conservative ideas, president of the undergraduate libertarians club
07.10.2025 02:06 β π 51 π 8 π¬ 0 π 0
what do you mean Eric Adams son competed on Albanian idol
07.10.2025 02:08 β π 0 π 0 π¬ 0 π 0
Scooby Miu Miu where r u
07.10.2025 00:43 β π 7 π 3 π¬ 1 π 0
#nw fallen leaves
07.10.2025 00:53 β π 0 π 0 π¬ 1 π 0
this administration is trying to kill me
07.10.2025 00:19 β π 2 π 0 π¬ 0 π 0
mahomes sells the town on the monorail and travis muscles the city council into voting for it
07.10.2025 00:06 β π 532 π 37 π¬ 9 π 0
I like that as soon as we as a species started having civilizations one of the first things we started doing was roasting pork. priorities
07.10.2025 00:14 β π 1 π 0 π¬ 0 π 0
Paul Musgrave β’ @profmusgrave
Around the department:
Americanists: how bad can it be really?
Comparativists: dictatorship, purges
International relations: nuclear war
2017-01-12, 9:18 AM
708 Retweets 944 Likes
Paul Musgrave Β© @profmusgrave β’ 2017-01-12
Replying to @profmusgrave
Americanists: haha but seriously
IR and comparative: who is joking
8
οΌ»189
194
Time for this evergreen banger.
19.08.2025 01:12 β π 70 π 6 π¬ 3 π 1
bro what the fuck is this shit
stop this
06.10.2025 20:22 β π 0 π 0 π¬ 0 π 0
"there are no atheists in foxholes" is a terrible expression. sure, the things that foxes worship do not resemble our "gods". that does not mean that they are atheists
29.03.2025 15:04 β π 385 π 87 π¬ 3 π 4
This is the main issue I have with so much of the coverage around e-bikes. It's not that there aren't legitimate issues. But there is a panic around e-bikes and crickets regarding the daily toll of cars. And that's because the harm of cars is just accepted. It's baked into our society.
06.10.2025 18:36 β π 384 π 87 π¬ 4 π 5
every email in the work inbox is dumber than the last π§
06.10.2025 17:55 β π 1 π 0 π¬ 0 π 0
Greta Thunberg: "I could talk for a very, very long time about our mistreatment and abuses in our imprisonment. Trust me. But that is not the story. What happened here was Israel⦠continuing to worsen and escalate their genocide and mass destruction with genocidal intent, attempting to erase an...
06.10.2025 17:12 β π 3692 π 1329 π¬ 17 π 95
A festive graphic with the text: βHappy Mid-Autumn Festival! δΈη§η―εΏ«ζ¨οΌβ
Best wishes for a peaceful and happy Mid-Autumn Festival!
06.10.2025 14:48 β π 70 π 13 π¬ 0 π 0
Journalist covering business, feminism, reproductive rights and a lot in between. Bylines: BBC, Observer, Prospect, New Statesman, The Persistent. βA little whiny and self-involvedβ.
Of course I have a Substack: https://bigfatnegative.substack.com/
Trade publishing's daily rundown, and sibling of the source of Deal Reports.
Writer, poker player and accidental quiz show host.
πβ€οΈβπ₯πΉ
Musician & astrologer
βSo long as I have five dollars in my pocket and some spaghetti, Iβm all rightβ - Fiorello LaGuardia
Long Island -> Florida -> Bronx -> Brooklyn
The Projectionist at The New York Times, and the author of βBlood, Sweat & Chrome: The Wild and True Story of Mad Max: Fury Roadβ
Not cowboy like Ally. Not at all
cuecuechmiquiliztli en mictlan
MSBWHT β’ π²π½
Political science PhD student. Worldβs third best Bigfoot colonial governance simulation expert. Had to drag myself kicking and screaming to she/her, but she/her nonetheless.
fashion enthusiast and y2k stuff π§πΌββοΈ (love posting off duty content)
i love margiela and hwang hyunjin
she her | 18β βπβΛβΉ
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Author of SOME OF MY BEST FRIENDS ('22) and TOUGH LOVE (forthcoming) / tajjaisen.com
Managing Director of Single Family Housing Inventory at BlackRock #DarkBlueSky
California writer. Ida Tarbell stan. Beat: tech fascism, billionaire extremism, network state, crypto cartels.
Writing a book: βThe Nerd Reich: Silicon Valley Fascism and the War on Global Democracy.β
The Nerd Reich: http://www.thenerdreich.com
Rhymes with Omni
co-creator/artist of FIRE POWER at Image Comics/Skybound
creator of JONNA AND THE UNPOSSIBLE MONSTERS at Oni Press
**please donβt color & repost my art**
The graphic joy of mid-century Eastern Bloc matchbox labels.
Prints available to buy online http://matchbloc.com
White House reporter for the Associated Press + CNN political analyst. Proud alum of the Washington Post and Politico.
baseball labor + econ journo, defector.com, etc; copy editor, @objectivejournos.bsky.social; "the most punk rock sports journo that's ever lived" -Nik; they/dude; π
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