Ray Berkeley

New preprint from Daniel Du @fitzpatricklab.bsky.social shows #femtosecond light pulses can lens electron beams, promising higher contrast in #cryoET and better aberration correction in #cryoEM

tinyurl.com/257sw7j9

Experiments made possible by support from @cziscience.bsky.social #ImagingTheFuture

This could be a good time to mention we are looking for a new Lab Manager / Postdoc for the biochemistry lab with expertise protein expression, purification, and protein NMR. Details to follow.

Research Scientist - Mass spectrometry - Ferguson Lab Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

Mass spec/proteomics chempostdoc in the Ferguson lab, UCSD, La Jolla, CA

chemsky 🧪 ⚗️

jobrxiv.org/job/universi...

Structural basis for the conformational protection of nitrogenase from O2 - Nature Cryo-electron microscopy of Azotobacter vinelandii FeSII–nitrogenase reveals a core complex of molybdenum–iron proteins (MoFePs), iron proteins (FePs) and FeSII, in which FeSII mediates interactions with MoFeP and FeP to position their FeS clusters in catalytically inactive but O2-protected states.

Nature research paper: Structural basis for the conformational protection of nitrogenase from O2

https://go.nature.com/4aiD344

Awesome work from Sarah, @bcryo.bsky.social and friends in the Herzik Lab! It was cool to see this come together in such a short time.

I like the inclusion of a picture the actual pond in Fig. 1A of this paper! Very serene, it sets the stage well.

Crosslinking intermodular condensation in non-ribosomal peptide biosynthesis - Nature Structural studies of tyrocidine synthetase using site-selective crosslinking probes to link condensation domains with carrier protein substrates define key interactions and molecular mechanisms of no...

Awesome application of biorthogonal chemistry to trap non-ribosomal peptide synthetase complexes for cryo-EM, out yesterday from the Burkart Lab @ucsandiego.bsky.social

www.nature.com/articles/s41...

What do they keep in here…