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Kristopher Sarosiek

@celldeathlab.bsky.social

The Sarosiek Lab @HarvardChanSPH studies the regulation of #apoptosis in human development and diseases, especially cancer.

220 Followers  |  325 Following  |  6 Posts  |  Joined: 12.11.2024  |  1.7742

Latest posts by celldeathlab.bsky.social on Bluesky

See you there! Monday April 7th at 3PM on the Harvard Med Quad. bostoncelldeath.org

24.03.2025 17:32 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Federal funding drives groundbreaking research at Harvard Chan School | Harvard T.H. Chan School of Public Health Harvard Chan faculty conduct groundbreaking research that has led directly to lifesaving vaccines, treatments, policies, and programs.

With support from federal funding, @hsph.harvard.edu faculty have conducted groundbreaking research that has led directly to treatments, policies, and programs that have saved lives by the millions, in the US and around the world.

Here are just three examples: hsph.harvard.edu/news/federal...

21.03.2025 13:51 β€” πŸ‘ 11    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0
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Boston Cell Death Initiative | Harvard T.H. Chan School of Public Health The Boston Cell Death Initiative brings together laboratories in the Boston area and beyond that work on various aspects of cell death.

➑️Join our next BCDI meeting for exciting discussions on programmed cell removal from Mounica Vallurupalli from the Broad Institute and NK-mediated targeting of tumor cells from Michal Sheffer from Dana Farber! Monday April 7th at 3PM on the Harvard Med Quad. bostoncelldeath.org

24.03.2025 12:44 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1

Join us for 2 great cell death discussions, Monday, March 3rd at 3PM on the Harvard Med Quad.! bostoncelldeath.org

22.02.2025 06:25 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Boston Cell Death Initiative

Boston Cell Death Initiative

➑️Join our next BCDI meeting for exciting discussions on Regulatory T Cell fate from Xudong Li @tufts and modulation of Gasdermin D function in pyroptosis from lab of Hongbo Luo @BostonChildrens! Monday March 3rd at 3PM on the Harvard Med Quad. bostoncelldeath.org

21.02.2025 11:20 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1

➑️Join us today at 3PM for the Boston Cell Death Initiative Discussion on #pericyte survival and #ferroptosis in hematopoietic stem cells! Goldenson 122 on the Harvard Med Quad.

03.02.2025 11:14 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

See you at the next BCDI discussion Monday Feb 3rd at 3PM on the Harvard Med Quad (Goldenson 122)!

21.01.2025 14:24 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Boston Cell Death Initiative | Harvard T.H. Chan School of Public Health The Boston Cell Death Initiative brings together laboratories in the Boston area and beyond that work on various aspects of cell death.

➑️Join our next BCDI meeting for not-to-be-missed discussions on pericyte cell survival for capillary integrity from Ke Yuan and preventing #ferroptosis in hematopoietic stem cells from @bloodgenes.bsky.social lab. Monday Feb 3rd at 3PM on the Harvard Med Quad. bostoncelldeath.

21.01.2025 11:22 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 2
This chart presents US cancer death rates in children under five years old, measured in reported annual death rates per 100,000 children. It consists of four graphs:

1. All Malignant Cancers Combined: This graph, shown in black, illustrates a decline in childhood cancer death rates from about 11 per 100,000 in 1950 to around 1.8 in 2021, indicating a six-fold decrease since the 1950s.
   
2. Leukemia: This graph shows a decrease from around 5 per 100,000 in 1950 to less than 1 in 2021, following a similar declining trend throughout the decades.

3. Brain and Nervous System Cancers: This chart shows some fluctuations but overall a decline from nearly 0.8 per 100,000 in 1950 to about 0.4 in 2021.

4. Lymphomas and Multiple Myeloma: This graph shows fluctuations and a decline from around 0.8 in the late 1950s to less than 0.2 by 2021.

The data is sourced from the WHO Mortality Database (2024), with a note indicating that figures may fluctuate year-by-year due to low numbers.

This chart presents US cancer death rates in children under five years old, measured in reported annual death rates per 100,000 children. It consists of four graphs: 1. All Malignant Cancers Combined: This graph, shown in black, illustrates a decline in childhood cancer death rates from about 11 per 100,000 in 1950 to around 1.8 in 2021, indicating a six-fold decrease since the 1950s. 2. Leukemia: This graph shows a decrease from around 5 per 100,000 in 1950 to less than 1 in 2021, following a similar declining trend throughout the decades. 3. Brain and Nervous System Cancers: This chart shows some fluctuations but overall a decline from nearly 0.8 per 100,000 in 1950 to about 0.4 in 2021. 4. Lymphomas and Multiple Myeloma: This graph shows fluctuations and a decline from around 0.8 in the late 1950s to less than 0.2 by 2021. The data is sourced from the WHO Mortality Database (2024), with a note indicating that figures may fluctuate year-by-year due to low numbers.

Childhood cancer deaths in the United States have declined six-fold over the last seventy years

09.01.2025 22:13 β€” πŸ‘ 109    πŸ” 16    πŸ’¬ 2    πŸ“Œ 10
Boston Cell Death Initiative

Boston Cell Death Initiative

➑️Join our next BCDI meeting for not-to-be-missed discussions on harnessing GSDMD-mediated cell death in cancer immunotherapy from Hao Wu's lab and neutrophil-derived vesicles from Hongbo Lou's lab. Monday Jan 6th at 3PM on the Harvard Med Quad. bostoncelldeath.org

30.12.2024 14:27 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
https://www.cell.com/cell/abstract/S0092-8674(24)01334-5

#NoTimeToDie! @vijayrathinam.bsky.social Weight &co show @cp-cell.bsky.social that pyroptotic cells release extracellular vesicles which transplant gasdermin D #GSDMD pores to neighboring cells propagating cell death! t.co/XgU6jt15aF Free link to the paper πŸ‘‰ authors.elsevier.com/a/1kMQgL7PXq...

31.12.2024 18:07 β€” πŸ‘ 19    πŸ” 7    πŸ’¬ 2    πŸ“Œ 0

Come join us for the first 2025 meeting of BCDI! Jan 6th 3-4pm, Goldenson 122 off the Harvard Quad

30.12.2024 17:02 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Boston Cell Death Initiative

Boston Cell Death Initiative

➑️Join our next BCDI meeting for not-to-be-missed discussions on harnessing GSDMD-mediated cell death in cancer immunotherapy from Hao Wu's lab and neutrophil-derived vesicles from Hongbo Lou's lab. Monday Jan 6th at 3PM on the Harvard Med Quad. bostoncelldeath.org

30.12.2024 14:27 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
Assistant Professor, Department of Molecular Metabolism The Department of Molecular Metabolism (MET) at the Harvard T.H. Chan School of Public Health invites applications for the level of assistant professor. The shared interest of MET faculty is to explor...

Join us in Boston! The Department of Molecular Metabolism (MET) at the Harvard T.H. Chan School of Public Health has just opened a Jr. Faculty search. Apply by January 15, 2025 at academicpositions.harvard.edu/postings/14371

21.11.2024 00:59 β€” πŸ‘ 29    πŸ” 17    πŸ’¬ 0    πŸ“Œ 2
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Kristopher Sarosiek's Faculty Website Researching Cell Death

We're looking for a hard working and ambitious postdoc to join our lab studying cell death in cancer, development, toxicology, neurodegeneration and beyond! We strive to maintain a diverse, inclusive and collaborative work environment.
Apply now at sarosieklab.org!

21.11.2024 10:50 β€” πŸ‘ 13    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1

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