Sam "The Mug Guy" Horrell 's Avatar

Sam "The Mug Guy" Horrell

@drhorrell.bsky.social

Scientist πŸ§‘β€πŸ”¬, structural biologist 🧬, X-ray Crystallographer πŸ’Ž, Synchrotron Mug Enthusiast β˜•, D&D 🎲 and MTG player πŸ§™, bird dad to Nori and Kili 🦜🦜 He/Him

953 Followers  |  1,494 Following  |  257 Posts  |  Joined: 22.09.2023  |  1.8223

Latest posts by drhorrell.bsky.social on Bluesky

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I'm currently at LCLS in Stanford, anyone got a lead on where I might find a #SynchrotonMug to add to my collection? I know they exist. I've seen pictures!

06.11.2025 19:51 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

All three are adorable thanks πŸ™‚

04.09.2025 18:34 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Finally, a detector suitable for the new SynchroGnome beamlines. A giant leap forward in tiny science.

#ROD10atECM #ECM

26.08.2025 12:16 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I don't have a Crystallography themed hat, so I guess I need to get one made out of something edible.

26.08.2025 12:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Why would we bother guessing anything else?

26.08.2025 12:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It's actually in P 21 21 21, but we can still meet up for that beer if you spot me at the conference.

25.08.2025 14:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Who are you wagering? Becuase I know the answer already πŸ˜‰

25.08.2025 12:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Disappointingly it was P21 21 21.

25.08.2025 12:36 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Made it to Poznan for the European Crystallography Meeting. Looking forward to presenting at the Science Slam on Thursday with the help of my cat Rosalind.

#Crystallography #ECM35 #StructuralBiology #ScienceCommunication #SciComm #ScienceSlam

25.08.2025 10:52 β€” πŸ‘ 13    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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a man with a beard is wearing a crown and saying you bow to no one . ALT: a man with a beard is wearing a crown and saying you bow to no one .

Top notch pun work. Truly immaculate.

20.08.2025 16:37 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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I don't want to alarm anyone, but I think my electron density might be haunted.

πŸ’ŽπŸ‘»πŸ’€

20.08.2025 15:46 β€” πŸ‘ 43    πŸ” 5    πŸ’¬ 2    πŸ“Œ 0
2 people, a woman wearing glasses and a man with a beard, taking a picture in the reflective surface of a photon counting detector.

2 people, a woman wearing glasses and a man with a beard, taking a picture in the reflective surface of a photon counting detector.

Said goodbye to the @dectris.bsky.social Pilatus 6M the other day with one last #DetectorSelfie featuring beamline scientist Sofia.

Collected some data to 0.87 A to give it a proper send off.

Not sure how many images it has taken on I24 but it is very deserving of a rest.

11.08.2025 18:02 β€” πŸ‘ 9    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Protein structure or #Minecraft Creeper?

19.06.2025 09:29 β€” πŸ‘ 15    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Taking bets on if this is crystalline or not. We'll find out next week on @diamondlightsource.bsky.social's VMXm next week with the help of @adamcrawshaw.bsky.social.

13.06.2025 09:50 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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The electron microscope can't believe you just said that.

05.06.2025 14:24 β€” πŸ‘ 28    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
A light yellow and grey cockateil and a dark grey peid cockateil put their heads together. One has their beak wide open. Both have very orange cheeks.

A light yellow and grey cockateil and a dark grey peid cockateil put their heads together. One has their beak wide open. Both have very orange cheeks.

After 2 weeks of antibiotics twice a day Nori (left) now has a clean bill of health.

Kili (right) is clearly pleased about this too.

29.05.2025 16:01 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A regular repeating pattern of Ale, Pau, and Danny from the  rock band The Warning. Effectively forming a 2D crystal of the band members.

A regular repeating pattern of Ale, Pau, and Danny from the rock band The Warning. Effectively forming a 2D crystal of the band members.

The reulsting diffraction pattern of the crystallised members of the warning. A Grey background with white spots in a regular repeating pattern.

The reulsting diffraction pattern of the crystallised members of the warning. A Grey background with white spots in a regular repeating pattern.

I was minding my own business watching a music video when suddenly I see @thewarningarmy.bsky.social have managed to crystallise themselves. So I thought I'd see if they diffract, and they do!

#Crystallography #TheWarning #Crystal #Diffraction

22.05.2025 10:36 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Naturally

16.05.2025 20:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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If this #crystal space group isn't P3 or P6 I'll eat my #crystallography hat.

It also reminds me of a tiny allen key.

15.05.2025 10:45 β€” πŸ‘ 26    πŸ” 1    πŸ’¬ 3    πŸ“Œ 0

I don't see a major and a minor groove, and there are fewer that 4 bases per turn.

08.05.2025 14:26 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Him: Structures in PDB format
Her: Do you mean mmCIF and not deprecated format, right?
Him: 
Her: RIGHT?

Him: Structures in PDB format Her: Do you mean mmCIF and not deprecated format, right? Him: Her: RIGHT?

Changes in PDB IDs are coming that will require use of PDBx/mmCIF file format... will you be ready? #MayThe4th
Resources are available to help: www.wwpdb.org/docume...

04.05.2025 16:12 β€” πŸ‘ 34    πŸ” 9    πŸ’¬ 2    πŸ“Œ 0
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Happy #StarWars day from Nori and Kili. May the fourth be with you.

04.05.2025 15:53 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Pretty successful draft at the local game store. Won the event and got a chonky dragon.

#MTG #MagicTheGathering

02.05.2025 22:03 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A black silicon chip with regular etched square holes covered in blue/purple crystals.

A black silicon chip with regular etched square holes covered in blue/purple crystals.

Blue copper crystals on a silicon chip.

01.05.2025 15:57 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Macrocyclic Peptide Probes for Immunomodulatory Protein CD59: Potent Modulators of Bacterial Toxin Activity and Antibody‐Dependent Cytotoxicity CD59 is an immunomodulatory cell surface receptor associated with human disease. Despite its importance in complement regulation and bacterial pathogenesis, CD59 remains a challenging therapeutic tar....

New paper out today on a cyclic peptide which interacts with CD59, a protein that inhibits the complement mediated membrane attack complex.

Some cool structural work went into this, modelling the cyclic peptide was an interesting challenge.

onlinelibrary.wiley.com/doi/abs/10.1...

01.05.2025 14:14 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I made Ojer Axonil spell slinger group slug and it has quickly become one of my favourites. First mono deck was Gisa Glorious Resurrector.

28.04.2025 21:59 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Β‘OlΓ©! Β‘OlΓ©! Β‘OlΓ©! WARNING!

Had a great time watching #TheWarning at Brixton last night.

18.04.2025 14:44 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

It's a protein called Isocitrate dehydrogenase 1 (IDH1). No salt crystals here.

16.04.2025 12:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Did someone say protein crystals?

Someone probably said protein crystals.

16.04.2025 09:37 β€” πŸ‘ 22    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Also a good shout

#PandemicFlashBacks

15.04.2025 15:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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