Adam Sharp

New drug combination to tackle advanced prostate cancer New drug combination to tackle advanced prostate cancer

NEWS 📰: New drug combination could tackle advanced #ProstateCancer

40% of advanced prostate cancer patients could be treated with a combination of 2 drugs. The drugs are already in use or in trials to treat cancer.

Read more about the work published in
@natcomms.nature.com ⬇️

Thank you

🚨 Delighted to share our latest paper, from
@asharpmedonc.bsky.social team in collaboration with Johann de Bono’s team at @icr.ac.uk and international colleagues, published in Nature Communications @natureportfolio.nature.com
Read here: bit.ly/477pYt7
🧵1/4

Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer. Jimenez-Vacas et al. (2025) Nature Communications.

Could targeting MCL1 be a new treatment approach for hormone therapy-resistant #ProstateCancer?

A study in @natcomms.nature.com by @juanjimenezvacas.bsky.social, @asharpmedonc.bsky.social and the @icr.ac.uk team explores precision therapy strategies.

Grab a ☕ and read: doi.org/10.1038/s414...

Waiting for the water to return. Still a 🏃 just not by 💦

A great talk Adam, really enjoyed hearing about the breadth of your work!

Thank you (for coming as well) 😊

Thanks for coming out today. A home game 🥰

We keep pushing. Wishing you all some Friday happiness 🥰.

Thanks 👀

Fitness 📉

Sleep seems to be optional currently! Big love to all 🥰

Thank you for the invite and the innovative format. Was great to chat with such an enthusiastic and engaged group. Super hospitality. Thank you for the awesome discussion 😊

So he has opted for our bed tonight with Mrs S. Double sleep divorce 😞

Timeline cleanse. Does this make me Batman 🥰

Jet lag is real.

The unit and sensitivity of measurement may change, but good is good and bad is bad, we may need more innovation to move from incremental to transformational.

One upon a time it was punter and pige - having now met @profiand.bsky.social @craiggedye.bsky.social in person - I have new favourite 🇦🇺!

We need to be mindful - we have little knowledge on how the androgen receptor works in prostate cancer. Remains a key area of research and for me the main target.

Thank you Seattle and San Fransisco for a lovely week. @fredhutch.bsky.social @ascocancer.bsky.social #GU

Loved this 😊

It’s real…. 😬

Morning Manchester!

Looking forward to #JING25 - annual meeting for early career researchers in experimental cancer medicine. Welcome to Manchester, everyone.
@cancerresearchuk.org @oncocook.bsky.social @mcrcnews.bsky.social @asharpmedonc.bsky.social @ukecrc.bsky.social
www.ecmcnetwork.org.uk/jing-tng

@annaminchom.bsky.social and I will be doing a very slow jog on Tuesday am at ECMC JING meeting. Meet in foyer around 7am. Plenty of time for it to be a social jog, shower and breakie before we begin day 2. Can’t wait (for the meeting)!

Huge thanks to you and your colleagues for all you do to improve outcomes for cancer patients and their families. Research is where hope starts!

We’re on our way! Looking forward to hearing from your researchers @icrlondon.bsky.social and the hope for prostate cancer patients in the future

An inspirational day for @pjmcg.bsky.social and me @icrlondon.bsky.social with @asharpmedonc.bsky.social and his team of researchers. Thanks for all you’re doing to bring hope to men with #prostatecancer. @ethansgrumps.bsky.social - great to meet you at last. Thanks for all you do too! ❤️

Beyond grateful to @ethansgrumps.bsky.social @sueduncombe.bsky.social @pjmcg.bsky.social for the time spent with our fabulous team @icrlondon.bsky.social. Supporting them develop the ability to describe complex science to public/patients and asking tough questions on how we translate to the clinic.

@ethansgrumps.bsky.social @sueduncombe.bsky.social @pjmcg.bsky.social all giving up their valuable time to visit the @icrlondon.bsky.social tomorrow and see what we are after. Very much looking forward to having them.