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Alexandra Colin

@alexandra-colin.bsky.social

CNRS researcher in the Cytomorpholab (Grenoble, France)

304 Followers  |  550 Following  |  12 Posts  |  Joined: 04.12.2024  |  2.2445

Latest posts by alexandra-colin.bsky.social on Bluesky

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Live on Oct 7, the MBoC 2025 Early Career Award Webinar (Part 1) runs 12–1 pm ET.

> Keynote: Margaret Gardel (UChicago)
> lightning talks from UCSF, UVM, ETH Zurich, Cambridge & Harvard
> moderation by John Aitchison

Free to attend β†’ www.ascb.org/ascb-meeting... #ASCB #CellBiology

24.09.2025 12:15 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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”Please inhibit responsibly: Natural and synthetic actin toxins as useful tools in cell biology”

I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!

www.molbiolcell.org/doi/10.1091/...

www.molbiolcell.org/cms/10.1091/...

16.09.2025 01:31 β€” πŸ‘ 34    πŸ” 13    πŸ’¬ 0    πŸ“Œ 1
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We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz β€” pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy.

mikeinmemoriam.sciencesconf.org

18.09.2025 08:50 β€” πŸ‘ 59    πŸ” 31    πŸ’¬ 0    πŸ“Œ 2
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Allocation of resources among multiple daughter cells. New study from Alison Wirshing, Daniel Lew and colleagues @mit.edu: rupress.org/jcb/article/...

#Cytoskeleton #Development

09.09.2025 14:16 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Flagellar gliding in choanoflagellates Freire-Delgado and Brunet discover a new mode of cell motility in choanoflagellates, the closest relatives of animals. Under mild confinement, choanoflagellate move over surfaces without cell deformat...

New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧡

09.09.2025 18:11 β€” πŸ‘ 209    πŸ” 86    πŸ’¬ 7    πŸ“Œ 7
Paris Cytoskeleton Day 2025 - Sciencesconf.org

Which city is the best for Cytoskeleton research?
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !

09.09.2025 12:32 β€” πŸ‘ 37    πŸ” 20    πŸ’¬ 2    πŸ“Œ 0

A new #UExM probe for #Actin!

Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !

Congrats to all !

If interested in #UExM, or #HAK-Actin, feel free to reach out !

Soon available at @spirochrome.com

#Expansion #Microscopy #ProtistsOnSky

28.08.2025 07:16 β€” πŸ‘ 45    πŸ” 19    πŸ’¬ 3    πŸ“Œ 0

πŸŒ±βœ‚οΈ How do plant cells decide where to divide?

Our work shows that actin can override the geometric rulesβ€”guiding cells to divide in alternative orientations.
#PlantScience #CellBiology #Arabidopsis

@camilagoldy.bsky.social @rdplab.bsky.social

www.biorxiv.org/content/10.1...

25.08.2025 08:34 β€” πŸ‘ 57    πŸ” 30    πŸ’¬ 3    πŸ“Œ 0
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Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...

21.07.2025 12:52 β€” πŸ‘ 50    πŸ” 22    πŸ’¬ 1    πŸ“Œ 0
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We have used many microwells to confine biochemical reactions in our recent studies. We wanted to share the protocol for preparing and characterizing microwells; this protocol is now published here : www.frontiersin.org/journals/cel...

@manuelthery.bsky.social @lblanchoin.bsky.social

17.07.2025 07:20 β€” πŸ‘ 28    πŸ” 7    πŸ’¬ 1    πŸ“Œ 1
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#science 🧬 | Non, ce ne sont ni les slips de Superman, ni ceux de Walter White dans Breaking Bad.

C’est une cellule ... et la mΓͺme photographiΓ©e 36 fois.
Sensation, adaptation, mΓ©moire… la cellule est plus futΓ©e qu’on ne le croit 🀯.

Pour en savoir plus πŸ‘‰ youtu.be/dX4rDXLJAdI

18.07.2025 07:17 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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We also give examples of imaging and functionalization to study actin-related processes.

17.07.2025 07:20 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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We detail the equipment and protocol for microwell manufacture, as well as characterization and quality control.

17.07.2025 07:20 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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We have used many microwells to confine biochemical reactions in our recent studies. We wanted to share the protocol for preparing and characterizing microwells; this protocol is now published here : www.frontiersin.org/journals/cel...

@manuelthery.bsky.social @lblanchoin.bsky.social

17.07.2025 07:20 β€” πŸ‘ 28    πŸ” 7    πŸ’¬ 1    πŸ“Œ 1
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πŸ”¬ From JCB’s July issue (rupress.org/jcb/issue/22...): a PtK2 cell plated on a micropattern and injected with low doses of soluble actin (orange) and tubulin (blue) in order to generate speckles along the corresponding filaments. From @manuelthery.bsky.social group (rupress.org/jcb/article/...).

14.07.2025 15:05 β€” πŸ‘ 24    πŸ” 5    πŸ’¬ 0    πŸ“Œ 3

this focused issue includes a great method by @alexandra-colin.bsky.social to make closed microwell in order to encapsulate your favorite reconstitution mix in compartments of controled size and shape. πŸ”΄πŸŸ₯πŸ”»β€οΈ

09.07.2025 17:17 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Frontiers | Reconstitution Methods in Cell Biology Reconstitution of cellular phenomena is a powerful approach for investigating the biochemical and biophysical processes that sustain life. Cell-free reconsti...

Interested in reconstitution methods? Love cell biology? Check out the accepted manuscripts in our Research Topic on Reconstitution Methods in Cell Biology! We are still open for submissions so if you're writing something exciting this summer, send it here: www.frontiersin.org/research-top...

09.07.2025 13:54 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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Want to brush up your French? Check the summary of our work with @stefvass.bsky.social, β€œPlongΓ©e au cΕ“ur de l'endocytose axonale”, just out in the June issue of MΓ©decine/Science! Open access here: www.medecinesciences.org/fr/articles/...
And we got the cover 😎

08.07.2025 09:08 β€” πŸ‘ 21    πŸ” 5    πŸ’¬ 3    πŸ“Œ 0

Come and Join our Dpt in Beautiful #Geneva !

We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.

08.07.2025 04:24 β€” πŸ‘ 34    πŸ” 25    πŸ’¬ 0    πŸ“Œ 0
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Registration and abstract submission for the 2025 SFP Physics & Life days are now open!
The meeting will be held on October 2-3 at the Institute Jacques Monod, Paris. Deadline: September 5.
phys-life-2025.sciencesconf.org?lang=en
@sfp-physique.bsky.social

@ijmonod.bsky.social

07.07.2025 10:54 β€” πŸ‘ 4    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1
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Evolutionary repurposing of a DNA segregation machinery into a cytoskeletal system controlling cyanobacterial cell shape Bacteria, despite their diversity, use conserved cytoskeletal systems for their intracellular organization. In unicellular bacteria, the ParMRC DNA partitioning apparatus is well known for forming act...

One of the most exciting discoveries from our lab so far is now online as a preprint!

Read a story on how the ParMR and Min systems started to collaborate to create the CorMR cytoskeleton, which now controls cell shape in multicellular cyanobacteria:
www.biorxiv.org/content/10.1...

02.07.2025 11:35 β€” πŸ‘ 83    πŸ” 36    πŸ’¬ 2    πŸ“Œ 5

Just out: we used SReD to measure the periodicity of spectrin rings along axons, finely capturing the effect of actin depolymerization. This and many more applications ➑️ www.nature.com/articles/s41...

Another great collab with @henriqueslab.bsky.social, congrats @afonsomendes92.bsky.social et al πŸ™

02.07.2025 12:20 β€” πŸ‘ 27    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

AML patient blasts exhibit polarization defects upon interaction with bone marrow stromal cells.

www.embopress.org/doi/full/10....

Work by Manuel Thery @manuelthery.bsky.social @institut-leucemie.bsky.social and co-workers.

02.07.2025 05:55 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Exciting news: our Board of Trustees has appointed @monicabettencourt.bsky.social as the CRG's new Director. Prof Bettencourt-Dias is expected to take up the post in 2026, replacing Dr. Luis Serrano, who will continue to maintain a research group at the institute.
www.crg.eu/en/news/moni...

01.07.2025 08:59 β€” πŸ‘ 96    πŸ” 18    πŸ’¬ 5    πŸ“Œ 7
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Les membres du Conseil scientifique de l'ENS-PSL partagent la vive inquiΓ©tude des personnels d'@universcience.bsky.social sur le devenir du @palaisdecouverte.bsky.social et s'associent Γ  la pΓ©tition en cours.

En savoir plus πŸ‘‰ https://bit.pulse.ly/b1pitkbaaa

26.06.2025 14:59 β€” πŸ‘ 5    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg  and Julie

A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg and Julie

🚨 JOB ALERT 🚨
We're hiring a Research Assistant – no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired πŸ§«πŸ”¬
Apply now πŸ‘‰ www.nature.com/naturecareer...

#STEMCareers #ResearchJobs

23.06.2025 13:00 β€” πŸ‘ 48    πŸ” 32    πŸ’¬ 1    πŸ“Œ 5

πŸ”¬ Vous souhaitez en savoir plus sur les mΓ©daillΓ©s 2025 de CNRS Biologie ?

πŸ“… Rendez-vous chaque jour pour dΓ©couvrir deux portraits de nos laurΓ©ats : leur parcours, leurs travaux, leur passion pour la recherche ! ‡️

17.06.2025 09:30 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Merci Adrien !

23.06.2025 05:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Merci Marie Emilie :)

22.06.2025 07:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Merci StΓ©phane !

19.06.2025 12:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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