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Subham Biswas

@subhambiswas.bsky.social

Core Facility Manager: High-Resolution Microscopy || PhD Student || Microtubules || Cytoskeleton || Microscopy ๐Ÿ”ฌ Biocytolab.com

63 Followers  |  104 Following  |  3 Posts  |  Joined: 11.01.2024  |  1.5348

Latest posts by subhambiswas.bsky.social on Bluesky

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๐ŸšจGreat News!๐Ÿšจ
Our latest preprint is now live on bioRxiv!
We show that MAP65-1 and PRC1 facilitate microtubule nucleation on pre-existing lattices, particularly at sites with structural defects associated with mechanical stress.

Congrats @marianattom.bsky.social

www.biorxiv.org/content/10.1...

16.09.2025 11:39 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Have you ever wondered how microtubules withstand and respond to mechanical stress in cells?

Here we show by in vitro reconstitution assays that MAP65-1 and PRC1 promote microtubule nucleation on existing lattices, especially on those with structural irregularities linked to mechanical stress.

16.09.2025 06:43 โ€” ๐Ÿ‘ 11    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

MAP65-1/PRC1 reinforces microtubules through nucleation https://www.biorxiv.org/content/10.1101/2025.09.14.676082v1

15.09.2025 23:31 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Are you ready for a symposium dedicated to microtubule dynamics, function, and structure? ๐Ÿ™Œ

#EESMicrotubules will bring together researchers who share an interest in microtubule biology and its relevance to health and disease ๐Ÿฉบ

๐Ÿ’ป s.embl.org/ees26-09-bl
โœ’๏ธ Submit your abstract by 11 March

11.09.2025 14:13 โ€” ๐Ÿ‘ 13    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Kinesin-induced buckling reveals the limits of microtubule self-repair https://www.biorxiv.org/content/10.1101/2025.09.08.672697v1

12.09.2025 21:48 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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Happy to share that our paper on Tau- Microtubule interaction is now published in Nature Physics!๐Ÿฅณ

We show that Tau isnโ€™t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.

Congratulations @subhambiswas.bsky.social!

www.nature.com/articles/s41...

11.09.2025 18:03 โ€” ๐Ÿ‘ 30    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Tau accelerates tubulin exchange in the microtubule lattice - Nature Physics Beyond its known role in stabilizing microtubules, it is now shown that tau protein actively promotes lattice defect repair by enhancing tubulin turnover at topological defects.

Excited to share that my paper on Tauโ€“Microtubule interactions is now published in Nature Physics!๐ŸŽ‰

Our work shows that tau goes beyond stabilizing microtubulesโ€”it also promotes the removal of defects in the microtubule lattice.

www.nature.com/articles/s41...

09.09.2025 11:56 โ€” ๐Ÿ‘ 30    ๐Ÿ” 12    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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๐ŸšจWe are hiring!!๐Ÿšจ
๐Ÿ“ขOur lab has two #ERC funded #PhD positions on an exciting project on cytoskeleton crosstalk to investigate how microtubules and vimentin intermediate filaments work together.

For additional details, visit: biocytolab.com/jobs/

Please share/repost!

23.01.2024 13:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

We have a PhD opening ๐ŸŽ“ at our lab in Saarbrรผcken, Germany!

The project focuses on interactions between microtubules and intermediate filaments in the cytoskeleton, โ€œcrosstalkโ€.

For additional information, visit: biocytolab.com

22.01.2024 08:19 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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