Eva Nowack

Congratulations, @messorensen.bsky.social!

A genomic catalog of Earth’s bacterial and archaeal symbionts Microbial symbiosis drives the functional and phylogenomic diversification of life on Earth, yet remains underexplored due to culturing challenges. This study employed machine learning (ML) to predict...

Interesting AI read. 15-23% of uncultivated microbes may engage in symbiotic relationships.

www.biorxiv.org/content/10.1...

By sidestepping the complexities of polycistronic transcription (typical for trypanosomatids like Angomonas) Lena’s new system lays the groundwork for a long-awaited conditional expression platform which will be a game changer for dissecting host-symbiont molecular interactions in real time.

T7 RNA polymerase-based gene expression from a transcriptionally silent rDNA spacer in the endosymbiont-harboring trypanosomatid Angomonas deanei Eukaryotic life has been shaped fundamentally by the integration of bacterial endosymbionts. The trypanosomatid Angomonas deanei that contains a β-proteobacterial endosymbiont, represents an emerging ...

Excited to share that our T7 RNA polymerase-based expression system brings a new level of versatility to Angomonas deanei as a model for studying endosymbiosis!
doi.org/10.1371/jour...

Fantastic news! Congrats!!!🎉

The Nowack lab temporary tattoos have arrived! Time to decide if you're team Paulinella or team Angomonas...

New vacancy in my team!

PhD student position on microbial genome evolution, focusing on the evolutionary principles underlying bacterial genome architecture.

Please repost and share with talented MSc students in #evobio, bioinformatics or related :)

www.uu.nl/en/organisat...

#MEvoSky #MicroSky

A gatekeeper for gene transfers - Nature Plants Large-scale genetic screening for plastid-to-nucleus gene transfers identifies that fast double-strand break repair functions as a key barrier for nuclear integration of organellar DNA and provides in...

With their clever setup to visualize ongoing endosymbiotic gene transfers (EGTs), Enrique Gonzalez-Duran, Ralph Bock and team reveal how double-strand break repair limits excessive EGT. Check out their new Nature Plants paper and my News and Views summary! www.nature.com/articles/s41...

If interested in developing a proposal around microbial endosymbionts in protists (Paulinella, Angomonas or other systems), contact me by PM or email. (2/2)

Interested in joining Heinrich Heine University Düsseldorf for a 2-year postdoc project? Next week (May 6-7) the popular HHU Marie S. Curie Master Class takes place again, an online event supporting you to develop a compelling proposal for the MSCA Postdoctoral Fellowship program. (1/2)

Join the GMI as a Junior Group Leader! The GMI is seeking a talented scientist to lead an independent research group, addressing fundamental questions in molecular plant biology. More information is below.

Credit: Margot Riggi (@margotriggi.bsky.social), Max-Planck Institute of Biochemistry (@mpibiochem.bsky.social)

Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6

Thank you!😊

Send your 'friend' over! I'll be happy to discuss!😆

The host-encoded dynamin-like protein ETP9 forms a contractile ring around the endosymbiont. ETP9 knock down results in division-impaired, filamentous endosymbionts before cells eventually die. 2/2

Angomonas deanei with flourescent-labeled nucleus and endosymbiont. ETP9 localizes at the endosymbiont division site.

Out today: Exciting intermediate between endosymbiont and organelle identified! Endosymbionts in Angomonas deanei lost nearly all bacterial cell division genes. Instead, we identified a host-encoded protein, ETP9, that became specialized for endosymbiont division. 1/2
www.science.org/doi/10.1126/...