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Dan Sloan

@sloanevolab.bsky.social

Molecular Evolutionary Biologist. Professor at Colorado State University Department of Biology. Personal account. Opinions my own (as if anyone else would want them). https://sites.google.com/site/danielbsloan

791 Followers  |  458 Following  |  68 Posts  |  Joined: 22.11.2023  |  1.753

Latest posts by sloanevolab.bsky.social on Bluesky

A 3D structural model of the plant mitochondrial ribosome shown from four angles, highlighting subunits affected by mitochondrial gene loss, nuclear transfer, and/or functional replacement in Silene conica.

A 3D structural model of the plant mitochondrial ribosome shown from four angles, highlighting subunits affected by mitochondrial gene loss, nuclear transfer, and/or functional replacement in Silene conica.

Pre-Thanksgiving preprint! Check out our first look at the proteomics of the wacky mitochondria of Silene conica and their translation machinery. Fun project with @jumpinggenomes.bsky.social, Amanda Broz, and Ryan Stikeleather!

www.biorxiv.org/content/10.1...

26.11.2025 16:06 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Research Associate-Fixed Term - East Lansing, Michigan, United States Position Summary The Lowry Lab at Michigan State University is searching for a postdoctoral research associate to conduct molecular and physiological experiments to understand the causes of genetic va...

I am currently searching for a new postdoctoral researcher to study the evolution, genetics, and physiology of cold acclimation and freezing tolerance in switchgrass at Michigan State University. This work will be funded by a newly funded five-year DOE grant. careers.msu.edu/jobs/researc...

20.11.2025 14:49 β€” πŸ‘ 58    πŸ” 79    πŸ’¬ 0    πŸ“Œ 2
Image showing 4 tRNAs being produced from only 2 loci, the tRNA genes completely overlap

Image showing 4 tRNAs being produced from only 2 loci, the tRNA genes completely overlap

Oh, your favorite genetic locus only encodes one gene? That's boring.

Amazing work from Jess Warren (www.hhmi.org/scientists/j...) to figure this out and prove it was real, given the wacky and challenging insect system we've got here.

www.biorxiv.org/content/10.1...

14.11.2025 20:06 β€” πŸ‘ 20    πŸ” 6    πŸ’¬ 3    πŸ“Œ 0

Matt, clearly we need a wrapper tool to run and aggregate output from all the CAFEs. CAPPUCCINO? Coordinated Aggregator of Pipelines Persistently Using Confusingly Common Identical Names Over and over

17.11.2025 22:13 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Professor & Head, Dept of Horticulture & Landscape Architecture Colorado State University invites applications and nominations for the position of Professor and Head of the Department of Horticulture and Landscape Architecture (HLA) in the College of Agricultural ...

We are looking for a new colleague and department head for #Horticulture and Landscape #Architecture at #Colorado State #University! #highered #academicsky #agsky #Agriculture. Apply by December 31! jobs.colostate.edu/postings/169...

16.11.2025 22:37 β€” πŸ‘ 20    πŸ” 20    πŸ’¬ 0    πŸ“Œ 0
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I am looking to hire a postdoc interested in combining genetics and evolution to understand why telomeres vary so much in plants. My group has been developing Mimulus a genetic model for studying plant telomeres and we have really cool research brewing. Please check ad for detail. Deadline is 12/31.

16.11.2025 20:29 β€” πŸ‘ 38    πŸ” 37    πŸ’¬ 0    πŸ“Œ 0
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U.S. Congress considers sweeping ban on Chinese collaborations Researchers speak out against proposal that would bar funding for U.S. scientists working with Chinese partners or training Chinese students

β€œThe prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”

14.11.2025 01:03 β€” πŸ‘ 593    πŸ” 315    πŸ’¬ 59    πŸ“Œ 278
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We are looking for a PhD student to work on an exciting plastid endosymbiosis in microbial eukaryotes. This position involves sampling, exciting microscopy such as CARDFISH, ExM and FIBSEM, single-cell transcriptomics and more. #protistsonsky 1/2

12.11.2025 09:50 β€” πŸ‘ 77    πŸ” 66    πŸ’¬ 2    πŸ“Œ 3
Wellcome Connecting Science hybrid conference 
Mutations in Time and Space

Conference dates: 13-15 April 2026 
Location: Hinxton Hall Conference Centre, UK and online. 

Bursary deadline: 12 January 2026
Abstract deadline: 2 February 2026
In-person registration deadline: 16 March 2026
Virtual deadline: 6 April 2026

Wellcome Connecting Science hybrid conference Mutations in Time and Space Conference dates: 13-15 April 2026 Location: Hinxton Hall Conference Centre, UK and online. Bursary deadline: 12 January 2026 Abstract deadline: 2 February 2026 In-person registration deadline: 16 March 2026 Virtual deadline: 6 April 2026

Explore the origins, patterns and consequences of mutations across biological systems! #MITS26

πŸ—“οΈ Conference dates: 13-15 April 2026

Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬

Check out our exciting speakers ➑️ bit.ly/4hmbnyr
#Genomics

27.10.2025 08:00 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1
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I am looking for a PhD student to start in my lab at UCSB in Fall 2026, studying evolutionary biology. See attached flyer for more information. Please also share with potentially interested students. Thanks!

03.11.2025 17:27 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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In situ architecture of the nuclear pore complex of the higher plant Arabidopsis thaliana - Nature Plants Using advanced imaging techniques and computer modelling, the authors were able to create a detailed structural model of a nuclear pore complex from a seed plant.

"...the higher plant Arabidopsis thaliana" πŸ€”

@natplants.nature.com you may want to edit the title!

www.nature.com/articles/s41...

03.11.2025 12:27 β€” πŸ‘ 37    πŸ” 4    πŸ’¬ 10    πŸ“Œ 1

Does anyone have examples of F32 supporting documents in the new format (starting August of this year) they'd be willing to share? We're specifically looking for goals, preparedness, training activities and timeline for an F32 resubmission for the December deadline. Any help very much appreciated! πŸ™

01.11.2025 17:57 β€” πŸ‘ 9    πŸ” 11    πŸ’¬ 0    πŸ“Œ 1
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Research Technician - Torii Lab Primary Work Address: 2500 Speedway, Austin, TX, 78712 Current HHMI Employees, click here to apply via your Workday account. About the Lab We are currently seeking a proactive Research Technician to s...

🧬πŸ§ͺResearch Technician Position Open🧬πŸ§ͺ
HHMI, UT Austin. Biochemistry/Biophysics- Assist recombinant protein expression, purification and structural analysis (protein NMR and CryoEM) to uncover the mechanisms of cell fate specification in plants.
hhmi.wd1.myworkdayjobs.com/en-US/Extern...

01.11.2025 19:41 β€” πŸ‘ 7    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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I'm really excited to help organize this workshop on #phylogenomics and #genome #evolution in the Czech Republic! The instructors are world-class!

Register to be part of the #phylogenomics and #genome #evolution workshop in Czechia! Registration closes November 15! evomics.org/apply-worksh...

01.11.2025 17:43 β€” πŸ‘ 15    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
A ceramic mug with a mitochondrial design on it

A ceramic mug with a mitochondrial design on it

Some slick mito gear hand made by one of our lab alums!

28.10.2025 18:37 β€” πŸ‘ 47    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Bumping this up one last time. I'm looking to hire graduate student(s) to work on an NSF-funded project to study elevational range shifts among dragonflies here in Colorado. @cudenverclas.bsky.social πŸ§ͺπŸŒπŸ™

Applications will be considered until Nov 1. See post below for more details

24.10.2025 12:24 β€” πŸ‘ 37    πŸ” 57    πŸ’¬ 0    πŸ“Œ 0

The GRFP announcement from NSF cuts out an entire cohort of 2nd year students from consideration, without warning. This is so deeply unfair that it warrants a formal protest from the scientific community. If someone wants to work with me to craft an open letter and solicit signatures, LMK.

26.09.2025 17:10 β€” πŸ‘ 171    πŸ” 88    πŸ’¬ 9    πŸ“Œ 9
Post image 18.09.2025 00:23 β€” πŸ‘ 778    πŸ” 189    πŸ’¬ 72    πŸ“Œ 15

Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.

Ie: it's not us (Samtools team)! Be warned

15.09.2025 08:40 β€” πŸ‘ 146    πŸ” 127    πŸ’¬ 2    πŸ“Œ 5
SMBE2026 - Call for Symposia Proposals

SMBE2026 - Call for Symposia Proposals

πŸ“’ The Call for Symposia for SMBE2026 is now open. We warmly invite you to submit a symposium proposal and help shape the scientific content of our annual meeting.

πŸ—“οΈ Key dates
Call for symposia: Sep. 1 - Oct. 15
Announcement of accepted symposia: Nov. 3

More information: smbe2026.org/symposia

09.09.2025 14:15 β€” πŸ‘ 14    πŸ” 12    πŸ’¬ 2    πŸ“Œ 2

I’ll be advertising a post-doc position (up to 3 year) soon. It will be for somebody that is a good programmer, interested in evolution & is keen to learn new machine learning & AI approaches. I don’t have a link to a job advertisement yet. The post will be hybrid working and based at U of Liverpool

09.09.2025 14:25 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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NSF Graduate Research Fellowship Program (GRFP)

The GRFP lives!! (due end of October)
www.nsf.gov/funding/oppo...

08.09.2025 18:23 β€” πŸ‘ 344    πŸ” 277    πŸ’¬ 6    πŸ“Œ 18

❀️❀️❀️ CSU. Fort Collins is a lovely place to live, and students / faculty are awesome. I should know, I taught there for 15 years! Apply!

08.09.2025 16:07 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Graphs showing plant responses to ribosome-stalling drugs as measured by photosynthetic efficient (Fv/Fm) and root length, with representative images of phenotypic mueasurements.

Graphs showing plant responses to ribosome-stalling drugs as measured by photosynthetic efficient (Fv/Fm) and root length, with representative images of phenotypic mueasurements.

New preprint on the role of MutS2 genes in rescuing stalled/collided ribosomes in chloroplasts, led by Amanda Broz and many other contributors from the lab. Never expected to go down this road when we started working on plant MutS2 years ago. Feedback appreciated!

www.biorxiv.org/content/10.1...

08.09.2025 19:49 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Assistant Professor Plant-Microbe Interactions We seek a creative, collaborative, and visionary plant biologist to establish an internationally recognized research program at the forefront of plant-microbe interactions aimed at understanding how t...

The Department of Biology at Colorado State University is hiring an Assistant Professor in the area of plant-microbe interactions! Please spread the word!

jobs.colostate.edu/postings/165...

08.09.2025 15:45 β€” πŸ‘ 74    πŸ” 138    πŸ’¬ 0    πŸ“Œ 1
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Low mutation rate but high male-bias in the germline of a short-lived opossum Abstract. Age and sex have been found to be important determinants of the mutation rate per generation in mammals, but the mechanisms underlying these fact

New paper led by @yadirapga.bsky.social!

Opossums have babies at 6-months of age, but are still highly male-biased in their mutations

academic.oup.com/genetics/adv...

01.09.2025 19:09 β€” πŸ‘ 31    πŸ” 18    πŸ’¬ 0    πŸ“Œ 0
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Collateral mutagenesis funnels multiple sources of DNA damage into a ubiquitous mutational signature Mutations reflect the net effects of myriad types of damage, replication errors, and repair mechanisms, and thus are expected to differ across cell types with distinct exposures to mutagens, division ...

In these dark times, it comes as a rare pleasure to highlight @natanaels.bsky.social ‬ & @marcdemanuel.bsky.social's work on germline and somatic mutations in humans. 1/n
www.biorxiv.org/cgi/content/...

02.09.2025 11:44 β€” πŸ‘ 107    πŸ” 46    πŸ’¬ 5    πŸ“Œ 2
Slide showing definition of epistasis: Interactions between alleles at different loci. The phenotypic effect of an allele at one locus depends on which alleles are present at another locus in the genome.

Slide showing definition of epistasis: Interactions between alleles at different loci. The phenotypic effect of an allele at one locus depends on which alleles are present at another locus in the genome.

On the same page there!

02.09.2025 00:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Cuz I thought epistasis only exists when there is variation at both loci, which is why the QG folks talk about "converting" epistatic to additive variance when an allele is fixed at one locus. Dude, all I know is that my confidence is shot next time I teach the Genetics kiddos about epistasis. Ha.

02.09.2025 00:08 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Don't you also need Ab and ab to show that it's an interaction?

01.09.2025 23:42 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

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