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Chris Marine Lab

@marinelab.bsky.social

Cancer research

1,567 Followers  |  318 Following  |  23 Posts  |  Joined: 15.11.2024  |  1.8542

Latest posts by marinelab.bsky.social on Bluesky


Big shout-out to Hadrien De Blander and huge thanks to all involved!

09.01.2026 16:40 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Simple cell geometry metrics reveal cancer cell diversity and plasticity and guide combination therapy Intra-tumour heterogeneity (ITH) and cellular plasticity contribute to therapy resistance. Single-cell transcriptomics is the gold standard for assessing ITH, but this approach remains costly and slow...

πŸš€ New preprint! Meet ORIGAMI: Mapping cancer cell state heterogeneity and plasticity, predicting and steering therapy-induced trajectories to rationalize genotype-agnostic combination strategies with only two physical metrics (cell surface area and volume)
www.researchsquare.com/article/rs-8...

09.01.2026 16:40 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 4    πŸ“Œ 1
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#highlycitedresearchers #vib #teamscience #researchexcellence #impactthroughcuriosity #whysciencematters | VIB PROUD IπŸπŸ— π•πˆπ 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐑𝐞𝐫𝐬 𝐫𝐞𝐜𝐨𝐠𝐧𝐒𝐳𝐞𝐝 𝐚𝐬 𝐂π₯𝐚𝐫𝐒𝐯𝐚𝐭𝐞 𝐇𝐒𝐠𝐑π₯𝐲 π‚π’π­πžπ π‘πžπ¬πžπšπ«πœπ‘πžπ«π¬ πŸπŸŽπŸπŸ“ Yes, you read that right. And we are beyond proud. But what does this actually mean? Every year, Clarivate highlights ...

www.linkedin.com/posts/vib_hi...

16.11.2025 21:40 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1
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Registration for Cancer Cell Plasticity closes on Monday 03 November!

Join us online to explore the fundamental mechanisms that control cancer cell plasticity at multiple biological levels:

eacr.org/conference/c...

29.10.2025 09:03 β€” πŸ‘ 5    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

Just like there are good and bad macrophages..., there are good and bad NK cells!! This has profound therapeutic implications, far beyond oncology! Thanks to CD for highlighting both papers and the superb and efficient editorial work! Thanks to our collaborators (especially Zihai Li) and funders!

09.09.2025 18:27 β€” πŸ‘ 18    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Unmissable for those working on melanoma and beyond.

09.07.2025 19:33 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Now online in Cancer Discovery for the #EACR2025 presentation by @marinelab.bsky.social: Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype doi.org/10.1158/2159... @vib-ccb.bsky.social @pozniakjoanna.bsky.social

18.06.2025 13:47 β€” πŸ‘ 17    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1

Very excited to see our new study out today - just in time for my talk annual EACR conference @helloeacr.bsky.social

18.06.2025 11:12 β€” πŸ‘ 16    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Fishing for melanoma metastasis-initiating cells in lymph nodes Nature Cancer - The complex nature of metastasis-initiating cells (MICs) has long hindered our understanding of how cancer spreads and how to prevent it. A study now identifies a potential MIC...

rdcu.be/emi9N
Fishing for Metastasis Initiating Cells (MICs): we summarize here a heroic effort from Christoph Klein and Melanie Werner-Klein labs, which describes a MIC population in lymph nodes and how these cells evade immune attack. #metastasis #melanoma #extracellularvesicles #cancerprevention

17.05.2025 08:25 β€” πŸ‘ 21    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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β€œScience has no passport, no gender, no ethnicity, no political party.”

EC President Ursula von der Leyen, announcing a €500M initiative to attract top global talent.

In a fractured world, science remains a unifying force – rooted in diversity, driven by curiosity, and shared by all humanity.

06.05.2025 11:26 β€” πŸ‘ 5638    πŸ” 1324    πŸ’¬ 169    πŸ“Œ 125

We are really looking forward to hosting YOU and these amazing speakers in Leuven. Whether you are a young trainee, an experienced postdoc or a leader in the field, please join us (you will not regret this!).

29.04.2025 12:57 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

An important step towards personalised (combination) cancer treatments. vib.be/en#/ We are very excited about this project! Thanks to Oliver Bechter and his team and Presage for their trust and vision.

01.04.2025 10:19 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Welcome back, Sarah!

01.04.2025 05:58 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Great talk from my friend and colleague @cedric-blanpain.bsky.social (Chemoresistance) at the @helloeacr.bsky.social conference on Drug Tolerant Persister Cells (Lyon, France). Thanks to the organizers for this exciting event.

19.03.2025 00:08 β€” πŸ‘ 16    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Please join us for this exciting event!!! Very much looking forward to the great talks and discussions on this πŸ”₯ topic

14.03.2025 14:57 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Our latest piece "Decoding Melanoma’s Cellular Mosaic to Unlock Immunotherapy Potential" is available online: authors.elsevier.com/a/1khFK3QxxS... and will soon be published in @cp-trendscellbio.bsky.social. Thanks to @pozniakjoanna.bsky.social for taking the lead! Our Cover design proposal is below

01.03.2025 04:34 β€” πŸ‘ 23    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Breaks are key to relaxed & unwind between sessions! This afternoon, @juliensage.bsky.social hit the courts with @marinelab.bsky.social & Lukas Dow - what better way to reset than a (maybe not so) friendly game of tennis🎾 #AMC25

28.02.2025 22:40 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Our excellent host, Julien Sage, sharing a surprising/unexpected role for T cells in the biology of small cell lung cancer …thanks Julien and Kevin for organising such a great @fusionconf.bsky.social (mouse models of cancer) conference!!

28.02.2025 20:53 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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We took a deep dive into cancer progressions & metastasis this morning at #AMC25:
🧬Chris Marine on melanoma progression & therapy resistance
🐭 Eran Andrechek & Peter Westcott with cutting edge mouse models
🫁Katie Politi on progression & resistance in lung cancer
🌊Plus an exciting Catamaran tour⛡️

27.02.2025 21:58 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

So cool!!

12.02.2025 21:59 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

So happy to see this live, Slim! Congratulations to you, Ernesto and the whole team for your resilience, vision and creativity!

10.02.2025 15:31 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

1) Huge thanks to @guccionelab.bsky.social @nickbarker @marinelab.bsky.social @ggargiul.bsky.social
@owensansom 4 the fantastic collaboration. NIH funding #EarlyStageInvestigator. Towards #BetterTherapeuticStrategies 4 #CRC patients #Oncofetal #CRC #IntratumoralHeterogeneity #PhenotypicPlasticity

10.02.2025 15:18 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Congratulations, Mark & co, on this beautiful and very important piece!

03.01.2025 09:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Congratulations Ginevra and the whole Fendt team! This is very exciting work!

01.01.2025 19:29 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

End-of-the-year preprint & first 🧡 where the sky is blue! Ever wondered how a cancer driven by a single mutant oncogene becomes molecularly & cellularly heterogeneous? Why metastases share drivers w/primary tumors but are more aggressive?

31.12.2024 13:12 β€” πŸ‘ 28    πŸ” 8    πŸ’¬ 3    πŸ“Œ 1

Auguri, Andrea! Congrats to the whole lab!!

18.12.2024 20:10 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Bioinformatician Postdoctoral Level - VIB Position summary The Chris Marine lab at the VIB Center for Cancer Biology (https://ccb.sites.vib.be/en) is actively seeking a skilled bioinformatician proficient in analyzing and integrating single-...

Looking for an enthusiastic bioinformatician (long-term postdoctoral follow or staff scientist) interested in cancer/melanoma biology and therapy resistance. Data Science (single-cell, spatial multiomics integration), Machine learning, R, Pyhthon... jobso.id/ik9e

17.12.2024 07:59 β€” πŸ‘ 23    πŸ” 18    πŸ’¬ 0    πŸ“Œ 0

Congratulations, Yael and team!

04.12.2024 12:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Congratulations, Anna and team!

29.11.2024 16:59 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The cellular dogma In this essay, I will put forth what I see as a major conceptual challenge for biology in the next decade, one that is inspired by Crick’s Central Dogma: understanding information flow in the cell in ...

www.cell.com/cell/fulltex...
My first post on BSKY will be a citation from Sydner Brenner (2002): "So genocentric has modern biology become that we have forgotten that the real units of function and structure in an organism are cells and not genes" highlighted by S Quake in this interesting piece.

15.11.2024 10:33 β€” πŸ‘ 21    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1

@marinelab is following 20 prominent accounts