Cohesin as an essential disruptor of chromosome organization
Cohesin is a multi-subunit molecular machine that is able to create lateral chromatin loops within a linear chromosome fiber. Despite intense study, a…
Plenty of work required to rigorously test the proposed hypothesis but my initial thoughts are this perspective by Adrian Bird in @cp-molcell.bsky.social may well be the most significant conceptual advance in the 3D genome organisation field in years:
www.sciencedirect.com/science/arti...
21.03.2025 23:19 — 👍 29 🔁 9 💬 3 📌 2
Peter MacCallum Cancer Centre https://commons.m.wikimedia.org/wiki/File:Eastern_entrance_of_the_Peter_MacCallum_Cancer_Centre_in_Parkville_(19_September_2024).jpg#mw-jump-to-license
Wrapping up my first week as a postdoc in the @meleckmas.bsky.social lab at @petermaccc.bsky.social!
Excited to be diving into epigenetic plasticity in cancer and looking forward to working with a fantastic team!
21.03.2025 09:14 — 👍 10 🔁 1 💬 1 📌 0
Wellcome Connecting Science laboratory and computational course
Low Input Epigenomics
Course dates: 9-16 May 2025
Location: Wellcome Genome Campus, UK
Application and bursary deadline: 18 February 2025
🔬 Deepen Your Chromatin Insights 🧬
Strengthen your understanding of an organism's #chromatin using low-input techniques, supporting your research at both the gene and genome-wide levels.
⏰ Apply for #LowInput25 training place by 18 February!
📎bit.ly/40fdETV
#ChromatinSky @nmaziak.bsky.social
12.02.2025 10:01 — 👍 1 🔁 3 💬 0 📌 0
Wellcome Connecting Science laboratory and computational course.
Low Input Epigenomics
Course dates: 9-16 May 2025
Location: Wellcome Genome Campus, UK
Application and bursary deadline: 11 February 2025
Do you want to explore the #chromatin of an organism?
Join our expert instructors at #LowInput25, and learn how to use low input techniques to support your #epigenomics research at the gene & genome-wide level
⏰Application deadline: 11 February
📎bit.ly/40fdETV
#ChromatinSky @nmaziak.bsky.social
13.01.2025 10:58 — 👍 8 🔁 5 💬 0 📌 1
We have had multiple discussions about why people have not previously observed the very dramatic reduction in transcription upon PNUTS depletion. So I looked at our own TT-seq data and analysed it without including the spike-in. The numbers speak for themselves! Spike-in calibration is important!
12.12.2024 10:49 — 👍 27 🔁 10 💬 1 📌 2
Hi Bluesky! I made a 3D chromatin starter pack.
Let me know if you would like to be added.
go.bsky.app/6tTQdqQ
13.11.2024 17:55 — 👍 84 🔁 42 💬 41 📌 0
Developmental and Stem Cell Biologist, interested in all things gene regulation. Transcription, lineage specification, potency and plasticity.
Associate Professor @ Penn Biology, Penn Epigenetics Institute, Penn Center for Genome Integrity.
We combine evolutionary genetics and cell biology to study how DNA repeat evolution perturbs and preserves genome integrity.
Cell aims to publish the most exciting and provocative research in biology. Posts by Scientific Editors on the Cell editorial team. See the latest papers at https://www.cell.com/cell/
Streaming the latest papers in evolutionary developmental biology
Website: https://evodevo.brunovellutini.com
Mastodon: https://biologists.social/@evodevo_papers
#EvoDevo #Papers #Research #DevBio #EvoBio
The preeminent Australian conference on the organisation and expression of the genome
Postdoc @broadinstitute.org @harvard.edu #MGH - Immunogenomics - PhD in Genomics🧬 @cam.ac.uk @sangerinstitute.bsky.social🔬 #LCG-UNAM
Scientist at IMP in Vienna. Excited about gene expression regulation and its encoding in our genomes - enhancers, transcription factors, co-factors, silencers, AI.
Husband. Father. Postdoc @ Svejstrup lab in Copenhagen studying transcription and DNA damage | EMBO & MSCA fellow
Jarocho de corazón, biochemist by training 🇲🇽
Group Leader Chromatin Architecture in Cancer Laboratory at UCD | Interested in Epigenetics, Chromatin, Transcription, Histone Modifications, Cancer | He/Him
Website: https://conwaychromatinlab.com/
Molecular & structural biologist CNRS with a big respect for Transcription Factors, RNA Pol II & Mediator
#CryoEM #ESR
Advocating for #basicresearch #womeninSTEM #preprint
Message in English or French.
https://bsi-lille.cnrs.fr
Stanford BioE, Genetics & Sarafan ChEM-H. Chan-Zuckerberg Biohub Investigator. Our lab develops and applies microfluidic assays for high-throughput biophysics and biochemistry.
Assistant Professor @ Stanford University | cancer epigenetics | DNA replication | protein synthesis | vanrechemlab.com
Assistant Professor, UBC school of Biomedical Engineering. Trying to enable personalized medicine by solving gene regulatory code.
Scientist in the School of Biotechnology and Biomolecular Sciences (BABS) at UNSW Sydney studying gene regulation and transcription factors in adipose tissue-resident immune cells and red blood cells
Deputy Director at WEHI, Melbourne Australia.
Lab head studying epigenetic control, in the context of X inactivation, genomic imprinting, SMCHD1, Prader Willi Syndrome, FSHD.
Mum, wife, beach lover.
Lecturer, researcher in CRISPR gene editing, epigenetics etc, and university administrator
Professor for Genetics interested in chromatin structure, histone variants and histone modifications and their roles in gene regulation and disease development.
Bloomberg Distinguished Professor of Structural Biophysics and Chromatin Biology at Johns Hopkins University, #Transcription #DNArepair #Chromatin #cryoEM
