The Pratt Group

Congratulations, Andreas and team - and welcome to BlueSky!

19.08.2025 11:40 — 👍 0    🔁 0    💬 0    📌 0

The first FASEB Ferroptosis conference! ✔️ Thank you to my co-organizer Scott Dixon, our sponsors, and the whole #Ferroptosis community for showing up and making this such a wonderful meeting! 🤩 ❤️

01.08.2025 18:07 — 👍 27    🔁 4    💬 1    📌 2

Home - Ferroptosis, Oxidative Stress, and Lipid Metabolism

FYI - We've extended abstract submission deadline to June 8. Submit soon to be considered for a short talk. Come join us at the first FASEB #Ferroptosis meeting! It's going to be awwwwesome! 🤩
events.faseb.org/event/11797f...

03.06.2025 16:24 — 👍 9    🔁 8    💬 0    📌 0

Lipid-degrading small molecule kills cancer cells by ferroptosis A molecule designed to activate iron locked up in organelles called lysosomes and thereby induce cell death might offer a way to tackle treatment-resistant cancer.

and the News & Views www.nature.com/articles/d41...

07.05.2025 15:48 — 👍 17    🔁 5    💬 0    📌 0

Activation of lysosomal iron triggers ferroptosis in cancer - Nature Some cancer cells exhibit high loads of reactive iron in lysosomes, and this feature is exploited by using fentomycin-1, a newly developed small molecule, to induce ferroptosis.

new out in Nature, very cool story www.nature.com/articles/s41...

07.05.2025 15:48 — 👍 30    🔁 11    💬 0    📌 1

Recommendations for robust and reproducible research on ferroptosis Nature Reviews Molecular Cell Biology - Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in...

Important walkthrough for newcomers in the field
rdcu.be/eg58p

09.04.2025 20:21 — 👍 14    🔁 9    💬 1    📌 2

This is literally what you get when you look for alcohol on the LCBO website. For those unfamiliar, the liquor control board of ontario is the LARGEST single purchaser of alcohol IN THE WORLD. Why? Because they buy for all of ontario.

04.03.2025 20:49 — 👍 15    🔁 1    💬 3    📌 1

The Chemical Institute of Canada

Deadline for #CSC2025 abstracts is approaching. “Chemistry Sings the Blues” is a symposium in celebration of the life and contributions of Dr. Willie Leigh. It is in the INORG division (ORG doesn’t allow symposia in honour of) but is open to all areas of chemistry. www.xcdsystem.com/cic/abstract...

28.01.2025 14:21 — 👍 3    🔁 2    💬 0    📌 0

Not opposite obviously, looked too quickly! You know what I mean…

11.12.2024 01:23 — 👍 1    🔁 0    💬 0    📌 0

The clock tower ;) Was Mark on the other side of that glass?

11.12.2024 01:21 — 👍 0    🔁 0    💬 1    📌 0

Western!

11.12.2024 01:19 — 👍 2    🔁 0    💬 1    📌 0

Congrats Kamyar and team! We are happy to have helped out. Very useful to have approved drugs to accelerate validation of ferroptosis inhibition as a therapeutic strategy!

22.11.2024 22:06 — 👍 2    🔁 0    💬 1    📌 0

Monitoring electrophilic intermediates in reactions of thiols in aqueous solution directly with 19 F NMR - Chemical Science (RSC Publishing) DOI:10.1039/D4SC04871G

No derivatization required! Thiol oxidation products (RSOH, RSCl, etc) can be observed and characterized directly using Dmitry’s water-soluble triptycene scaffold. Check it and some cool applications out now in ChemSci! pubs.rsc.org/en/content/a... @roysocchem.bsky.social

21.11.2024 13:20 — 👍 8    🔁 1    💬 1    📌 0

Ligand-Based Radical Reactivity of Metal Thiosemicarbazones Prompts the Identification of Platinum(II)-Based Cytoprotectants CuATSM, a copper(II) complex of a bis(thiosemicarbazone) of diacetyl, prevents oxidative cell death and acts as a neuroprotectant in vivo, prompting its evaluation to treat amyotrophic lateral scleros...

First post on the new (to us) platform! Now out with page numbers: Mike and Aditya inhibit #ferroptosis with platinum complexes!? You read that right… platinum is not just for killing cells! Check it out in JACS: pubs.acs.org/doi/abs/10.1...

19.11.2024 22:33 — 👍 19    🔁 3    💬 2    📌 0