Join us today to hear from Ann-Sophie Paschke and Stefanie Schiele from the @morandilab.bsky.social about their work on C-to-N atom swapping reactions!! Thanks to Karim for hosting and editing!
Link: youtu.be/D513hX1gOTg
@chemicalscience.rsc.org
doi.org/10.1039/D5SC...
09.08.2025 13:38 β π 1 π 0 π¬ 0 π 0
YouTube video by Synthesis Workshop Videos
Non-enzymatic Methylcyclization of Alkenes with Immanuel Plangger
Join us this week on Synthesis Workshop as Immanuel Plangger shares his work on the development of a non-enzymatic methylcyclization reaction!! Thanks to Fabrizio Politano for hosting and editing!
Link: youtu.be/fnFfw9T5DTM
Key paper:
Nat. Chem. 2025, 17, 904β910.
doi.org/10.1038/s415...
19.07.2025 22:15 β π 0 π 0 π¬ 0 π 0
Very excited to announce that our recent review has been featured on the cover of Synthesis!!
If you haven't had a chance to check it out yet, here is a link to the review: doi.org/10.1055/a-26...
18.07.2025 14:31 β π 0 π 0 π¬ 0 π 0
Join us this week as Jonathan Gruhin @alexanian-lab.bsky.social shares his work on the homologation of carboxylic acids! Thanks to Alicia Wagner for hosting and editing!!
Link: youtu.be/hbrrRyy0zfU
Key paper:
J. Am. Chem. Soc. 2024, 146, 48, 32919β32924
doi.org/10.1021/jacs...
12.07.2025 19:08 β π 1 π 0 π¬ 0 π 0
Dive into chiral #DrugDevelopment π This review by Γlvarez-Calero & Horwitz @synthesisworkshop.bsky.social highlights efficient, scalable #API synthesis for new drug substances. Discover how asymmetric synthesis drives #pharma innovation via diverse case studies π§¬
π buff.ly/ganycgH
02.07.2025 07:01 β π 1 π 1 π¬ 0 π 0
YouTube video by Synthesis Workshop Videos
Concise Synthesis of Isosteroidal Alkaloids with Michael Zott and Daniel Zuschlag
Join us today as Michael Zott and Daniel Zuschlag share their work with Prof. Dirk Trauner on the synthesis of isosteroidal alkaloids!!
youtu.be/Be-vVFLuGzE
Key reference: J. Am. Chem. Soc. 2025, 147, 3010-3016. doi.org/10.1021/jacs...
21.06.2025 14:39 β π 0 π 0 π¬ 0 π 0
Today Γmer TaΕpΔ±nar joins us to share his work from the Clayden group on asymmetric intramolecular arylation reactions in a virtual research poster!!
Check out the full paper, published under a month ago in Angewandte Chemie here: doi.org/10.1002/anie...
04.06.2025 19:42 β π 0 π 0 π¬ 0 π 0
This is just one example of the problems you'll find in our latest problem set on covalent and noncovalent organocatalysis!! Check out the full set at synthesis-workshop.com in the Problem Sets or Courses section (see the Asymmetric Organocatalysis course).
26.04.2025 20:42 β π 0 π 0 π¬ 0 π 0
YouTube video by Synthesis Workshop Videos
Introduction to Asymmetric Organocatalysis: Non-covalent Organocatalysis
Check out the latest installment in our Asymmetric Organocatalysis course!!
Link: youtu.be/pwtS9YWxldI
Once you're done, head over to synthesis-workshop.com and check out the corresponding problem and solution set! You can find it either in the Problem Sets or Courses section.
26.04.2025 20:40 β π 0 π 0 π¬ 0 π 0
Join us this week as Rahul Giri shares his work on dual-functional group transfer reagents for the dihalogenation of hydrocarbons!! Thanks to Andy for hosting!
Link: youtu.be/eL7dFssUHcA
28.03.2025 20:23 β π 1 π 1 π¬ 0 π 0
YouTube video by Synthesis Workshop Videos
eFluorination for the Rapid Synthesis of Carbamoyl Fluorides from Oxamic Acids
Join us this week to hear from Dr. Feba Pulikkottil about her recently published work on eFluorination!!
Link: youtu.be/U6V6rYhMu1A
Key paper: Org. Lett. 2024, 26, 29, 6103β6108 doi.org/10.1021/acs....
22.03.2025 14:21 β π 0 π 0 π¬ 0 π 0
YouTube video by Synthesis Workshop Videos
Site-selective Arylation and Alkylation of Glycines and Peptides with Prahallad Meher
Join us today on Synthesis Workshop as Prahallad Meher shares his work on site-selective alkylation and acylation reactions on glycines and peptides!! Thanks to Matteo Balletti for hosting!
Link: youtu.be/D7GsRePvxSs
Key paper:
ACS Catal. 2024, 14, 18896-18906.
doi.org/10.1021/acsc...
15.03.2025 14:35 β π 1 π 0 π¬ 0 π 0
Join us today as NicolΓ² Tampellini shares his recently published work on asymmetric cyclization reactions!!
Link: youtu.be/9e4Hxt5FjH4
J. Am. Chem. Soc. 2025, 147, 4624-4630.
doi.org/10.1021/jacs...
08.03.2025 14:32 β π 3 π 0 π¬ 0 π 1
Also check out our new problem and solution set on synthetic electrochemistry, created by Dr. Peter Bellotti! Available for download for free on our project homepage in the Courses or Problem Set section (www.synthesis-workshop.com)!
05.03.2025 21:16 β π 0 π 0 π¬ 0 π 0
Tune in for an β‘β‘β‘ELECTRIFYINGβ‘β‘β‘ talk!
Today we release our introductory mini-course on synthetic electrochemistry, led by Dr. Max Palkowitz and hosted by Alicia Wagner!!
Link: youtu.be/pBW4xHF2bBw
05.03.2025 21:14 β π 8 π 1 π¬ 0 π 0
Welcome to the team!!!
21.02.2025 05:31 β π 0 π 0 π¬ 0 π 0
Join us this week to hear from Enric Adillon about his work on a carborane-derived proton-coupled electron-transfer reagent!! Thanks to Matteo Balletti for hosting!
Link: youtu.be/PDAUl-I8e3g
Key reference:
J. Am. Chem. Soc. 2024, 146, 30204-30211.
doi.org/10.1021/jacs...
14.02.2025 20:29 β π 1 π 0 π¬ 0 π 0
Did you like our Advanced Organic Chemistry course Good news! You can now download all the PDFs on our project homepage: synthesis-workshop.com#downloads
Haven't seen the course yet? Check it out!
www.youtube.com/playlist?lis...
08.02.2025 16:17 β π 1 π 0 π¬ 0 π 0
A sneak peak of the incredible finale of this talk!
07.02.2025 20:27 β π 0 π 0 π¬ 0 π 0
Tune in to see an incredible recent total synthesis, explained by Hiroshige Ogawa!! Thanks to Kathleen for hosting!
Link: youtu.be/qVz9znlbeFg
@angewandtechemie.bsky.social Int. Ed. 2024, e202414295.
doi.org/10.1002/anie...
07.02.2025 20:27 β π 1 π 0 π¬ 1 π 0
YouTube video by Synthesis Workshop Videos
Sulfoxylate-Mediated Aldehyde-Olefin Coupling with Zhihang Li
Tune in this week as we're joined by Zhihang Li, who shares his recently published work on sulfoxylate-mediated aldehyde-olefin coupling! Thanks to Aidan Looby for hosting and editing!
Link: youtu.be/0r_svfWvQYM
Key paper:
J. Am. Chem. Soc. 2024, 146, 26616β26621.
doi.org/10.1021/jacs...
01.02.2025 14:23 β π 1 π 0 π¬ 0 π 0
Check out our latest Research Spotlight with Liam Franov on electroinduced alkene-aldehyde couplings!
Link: youtu.be/_gDvUnRoWag
Key paper:
J. Am. Chem. Soc. 2024, 146, 29450-29461.
doi.org/10.1021/jacs...
26.01.2025 14:37 β π 1 π 0 π¬ 0 π 1
YouTube video by Synthesis Workshop Videos
Advanced Organic Chemistry: Introduction to Photoredox Catalysis
Curious about photoredox chemistry but don't know where to start? Start here! In this amazing introduction to photoredox catalysis, Dr. Tracy Liu takes us through the core concepts of the field!
youtu.be/JnUI0QoloVc
23.11.2024 14:21 β π 2 π 0 π¬ 0 π 0
YouTube video by Synthesis Workshop Videos
Synthesis Workshop: Demystifying the Soai Reaction with Dr. Soumitra Athavale (Episode 47)
Like detailed mechanistic studies? Then you'll love this talk by Dr. Soumitra Athavale on unraveling the incredible and mysterious Soai reaction!
youtu.be/mMyJ5hcKQ_Q
Reference: Nat. Chem. 2020, 12 , 412-423.
23.11.2024 14:18 β π 1 π 0 π¬ 0 π 0
YouTube video by Synthesis Workshop Videos
Total Synthesis of Maximiscin, A Natural Product with Anticancer Properties
For a great total synthesis throwback (hard to believe it's been 4 years), check out our highlight of the Baran group's approach to maximiscin!
youtu.be/iiZUaqeXGzs
Reference: J. Am. Chem. Soc. 2020, 142, 8608-8613.
23.11.2024 14:16 β π 0 π 0 π¬ 0 π 0
Advanced Organic Chemistry (Synthesis Workshop Course) - YouTube
This is an open access graduate-level course on advanced organic chemistry, which covers many topics covered in standard graduate-level classes, but also man...
This is our first post here! If you're just learning about Synthesis Workshop, check out our open access Advanced Organic Chemistry course: www.youtube.com/playlist?lis...
For much, much more, check out our project homepage: synthesis-workshop.com
23.11.2024 14:06 β π 0 π 0 π¬ 0 π 0
Organic synthesis, organometallic reaction development, and radical C-H functionalization at UNC Chapel Hill
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