RNAConnect

UltraMarathonRT Direct RNA-Seq Kit now available for ordering!

Now Available!

The UltraMarathonRT® Direct RNA‑Seq Kit is compatible with your existing ONT protocol, designed to generate higher cDNA yields and improved performance on long/structured RNAs.

Order now: bit.ly/4ju71Xl

#RNA #RNAseq #NGS #nanopore #LongRead #RNASky

Read the latest RNAConnect publication titled Improved long-transcript representation in Oxford Nanopore direct RNA sequencing with UltraMarathonRT

Ditch the doomscrolling and read the latest data showing how uMRT can improve your ONT direct RNA-Seq.

Highlights:
• Notable gains for >5 kb
• ↑ NIC & NNIC + ↑ intron retention
• +~25% higher cDNA yield

Dive into the data → www.biorxiv.org/content/10.6...

#RNA #RNAseq #DRS #cDNA #RNASky

Press release 🔗 bit.ly/3MD4MEF

Press release: RNAConnect Launches the UltraMarathonRT Direct RNA-Seq Kit to Advance Nanopore-based Native-RNA Sequencing

The UltraMarathonRT® Direct RNA‑Seq Kit preserves and detects longer #RNAs and reveals more isoforms per gene.

This kit offers a simple drop‑in fit to your #Nanopore SQK‑RNA004 workflow.

See how it expands what you can learn from every #longread seq sample.

PR🔗below.

#RNASeq #DRS

More Data from Each RNA Sample with Less Bias UltraMarathonRT cDNA Synthesis & Amplification Kit

What if you could see more transcripts from each of your #RNA samples?

uMRT has been engineered to efficiently copy even the most difficult RNA targets, including:

🔹 Highly structured RNAs
🔹 Long transcripts (≤20kb)
🔹 High GC content regions
🔹 Non-coding RNAs

Learn more: bit.ly/488ScFO

rnaconnect.com/pages/umrtcd...

Reveal What Retroviral RTs Miss.

Unlock deeper RNA-seq insights with uMRT, including:
🔹 Low-abundance transcripts
🔹 High GC content regions
🔹 Unique isoforms
🔹 Non-coding RNAs
...and more

Enhance your RNA-seq today! Read more in the comments below...

#RNASeq #RNA #GeneDetection #BioTech

uMRT has been engineered to deliver ultra-processivity at 30°C. It copies every RNA end-to-end in a single pass, which reveals more genes, transcripts, isoforms, and even twice as many retained introns as leading retroviral RT kits.

Learn more: bit.ly/488ScFO

#GeneDetection #RNASeq

Efficient circRNA Detection Using the Processive Reverse Transcriptase uMRT Circular RNAs (circRNAs) are covalently closed RNA molecules known for their increased stability compared to linear RNAs. Synthetic circRNAs are being developed as RNA therapeutics, while natural circ...

Pub 🔗https://bio-protocol.org/en/bpdetail?id=5480&type=0

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Pub highlights:
• Improved read-through of structured regions at ambient conditions
• Accurate and efficient cDNA concatemer generation from circular RNA
• Fewer steps to sequence the concatemeric RT PCR product directly
• Applicable to synthetic and natural circRNAs, from short to very long

[1/2] A new publication from Warkentin & Pyle presents a practical workflow for accurate circRNA detection using UltraMarathonRT® (uMRT), a highly processive reverse transcriptase.

Pub 🔗 in the comments.

#cDNA #RNA #RNAseq #circRNA #RTPCR #RNASky

We’re excited to (RNA)Connect with you at #ASHG25!

Visit Booth #121 to discover how uMRT reveals more from every RNA sample.

▪️ 10–30% more genes detected
▪️ Superior quantification of long transcripts

See what your #RNASeq data has been missing.

#RNA #cDNA #RNASky #transcriptomics #genomics

We’re live at ASHG 2025 — exhibit hours begin today from 9:30 am to 4:30 pm!

Stop by Booth #121 to chat with the RNAConnect team and discover how UltraMarathonRT® can enable you to reveal more of the transcriptome.

#ASHG25 #RNA #Genomics #Transcriptomics #RNASky

Single-cell RNA-seq using UltraMarathonRT expands the known transcriptome The ability to map messenger RNA (mRNA) molecules from individual cells using next-generation sequencing technologies, known as single-cell RNA-seq (scRNA-seq), is transforming biology by redefining c...

www.biorxiv.org/content/10.1...

Congrats to Chia-Ling Chou, Emmanuel Saliba, Anna Marie Pyle, Li-Tao Guo and co-authors on demonstrating how single-cell RNA-Seq with UltraMarathonRT® reveals unexpected transcriptomic diversity.

🔗👇

@emmanuel-saliba.bsky.social @litaoguo.bsky.social

#singlecell #scRNAseq #RNA #RNAresearch #RNASky

Learn more: bit.ly/488ScFO

The new UltraMarathonRT® (uMRT) cDNA Synthesis & Amplification Kit reveals more information from every RNA sample.

RNAseq has been limited by retroviral RTs for too long.

The latest uMRT Kit reveals more information from every RNA sample.

Unlock:
▪️ 10-30% more genes
▪️ More reliable gene quant
▪️ Improved gene body coverage with less bias
▪️ Detects 2x more retained introns

#RNASeq #NGS #RNASky

Read the white paper: bit.ly/3K9RxKy

uMRT RT-qPCR provides more reliable results with consistent Ct values and full-length cDNA every time

You may be getting biased or inaccurate results from your RT-qPCR kit and not even know it.

Our new white paper shows how UltraMarathonRT® delivers robust, reliable results regardless of primer choice and outperforms leading retroviral RTs.

🔗Link in comments.

#RTqPCR #qPCR #RNASky

RNA Connect | UltraMarathonRT cDNA Synthesis & Amplification Kit Maximize insights from your short-read RNA-seq with the UltraMarathonRT® cDNA Synthesis & Amplification Kit. With intrinsic helicase activity, UltraMarathonRT makes full length cDNA from RNA templates...

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Engineered for ultraprocessivity and sensitivity, uMRT makes faithful cDNAs of even the longest, most structured, and low-abundance RNAs - which retroviral RTs simply can’t do.

Reveal more of the transcriptome: bit.ly/488ScFO

[1/2] Now Available!

The new UltraMarathonRT® (uMRT) cDNA Synthesis & Amplification Kit delivers better gene detection and quantification.

#RNAseq #RNASky #Transcriptomics #ReverseTranscriptase #NGS

American Society of Human Genetics (ASHG) 2025 🗓 Date: October 14-18, 2025📍 Location: Boston, MA We look forward to seeing you at the American Society of Human Genetics (ASHG) Annual Meeting. As the genomics and transcriptomics fields continue to ...

Learn more: rnaconnect.com/blogs/news-r...

Join RNAConnect at ASHG 2025

Join us at booth 121 during #ASGH25 to learn how uMRT can provide you with more accurate gene expression profiles and reveal more isoforms, novel splicing, and previously undetectable intron retention events.

#ASHG2025 #RNA #RNASky #Transcriptomics #IntronRetention #Genomics #RNASeq #NGS

RNAConnect® Announces Commercial Launch of UltraMarathonRT® cDNA Synth Branford, CT, August 27, 2025 — RNAConnect, a leader in next-generation molecular biology tools, today announced the commercial launch of the UltraMarathonRT cDNA Synthesis and Amplification Kit, desi...

Read the full PR here: bit.ly/3JzqRTa

Now available: UltraMarathonRT® cDNA Synthesis & Amplification Kit!

Elevate short-read #RNAseq with unmatched processivity: detect rare isoforms & #lncRNAs, quantify long transcripts, and integrate seamlessly with Illumina®-style workflows.

Press release🔗in the comments.

#RNASky #transcriptomics

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UltraMarathonRT naturally unwinds RNA’s secondary structures, copies through mods and enables the detection of far more ncRNAs of any size.

With noncoding RNAs rewriting the rules of molecular biology, UltraMarathonRT, can aide researchers in reading their full stories.

[1/2]

"The 21st century, Thomas Cech says, 'is the age of noncoding RNA.'"

We agree with Dr. Cech. Since ncRNAs can be long, structured, and modified, they’re often tricky to characterize.

So, we developed the solution: a next-generation RT, UltraMarathonRT.

#RNASky #RNA #ncRNA #noncodingRNA

These winners are innovators in the thriving RNA research community—and use the unique power of uMRT to do it.

We’re proud to announce our support of their scientific pursuits on RNA Day! 🥳

@yalerna.bsky.social @thernainstitute.bsky.social

We’re celebrating #RNADay by spotlighting the four winners of the RNAConnect 5K Sprint Award!

🥇 First Place
Dr. Melissa Jurica (UC Santa Cruz)
Dr. Daniel Kiss (Houston Methodist)

🥈 Second Place
Dr. Andrew Berglund (Univ at Albany)
Dr. Mark Williams (Yale School of Medicine)

#RNASky