Rebee

Viral protease-mediated polyprotein processing in human astroviruses Positive-sense RNA viruses often encode large polyproteins that are proteolytically processed by viral and host proteases into functional replication proteins. Astroviruses infect intestinal and neuro...

New preprint: Viral protease-mediated polyprotein processing in human astroviruses

Great collaboration with Lulla lab. And the first of @leandroxneves.bsky.social proteolysis stories. More coming soon!

www.biorxiv.org/content/10.1...

Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis The reliability of single-cell proteomics (SCP) is intrinsically linked to the fidelity of cell isolation; however, the identification of co-isolated cells (doublets or multiplets) remains a persisten...

New preprint from the lab, and joint first authors @biomarkella.bsky.social and @stephenholmes.bsky.social!

Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis

www.biorxiv.org/content/10.6...

big moves!

so that's

Parse -> Qiagen
Scale -> 10X Genomics
Fluent -> Illumina

next-gen single-cell cell omics, capable of processing 10^6 to 10^8 cells

i wonder if what the near term looks like - will commercial kits stagnate while the buyers rebrand?

Te Tiriti obligations don't disappear just because the government claims they're not necessary.

He Whakaputanga and Te Tiriti o Waitangi are the foundation on which Aotearoa stands, and continue to have legal authority. Without them, there is no kāwanatanga.

www.archives.govt.nz/discover-our...

Identification of Capture Phases in Nanopore Protein Sequencing... arxiv.org/abs/2511.0...

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#proteomics #prot-preprint

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery High-fidelity Nanopore sequencing offers a cost-effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read-length bias, low throughput, and limited ...

RNA Virus Journal Club – Upcoming Talk - this thursday (Nov 6th !)

With @rdrpsummit.bsky.social - excited to announce talk and discussion with Dr Sanguu Kim about HF nanopore sequencing strategy for virology :)

calendar.app.google/oyRVP6v5Tvjg...
CET: 14:00–15:00,
Format: 30 min + 30 min

Only certain types of bats host viruses with high epidemic potential, research suggests Those found in coastal South America, Southeast Asia, and equatorial Africa are more likely to carry pathogens such as SARS-CoV-2.

www.cidrap.umn.edu/covid-19/onl...

Photograph of mounted great false vampire bat (Vampyrum spectrum) against light green background in the collections of the Cole Zoology Museum (University of Reading). Its wings are fully extended and it has sharp teeth. It looks very scary.

🦇🩸⚰️ Happy Halloween! 🧛🩸🦇

Same-sex sexual behaviours in bats were first documented in 1895! Here's a more recent study: www.italian-journal-of-mammalogy.it/Same-sex-sex...

#Halloween #HappyHalloween #histsci #histbio #STS #GLAM #queer #lgbtq #queernature #PrideInSTEM 🌈🗃️

A news title card that reads ’First evidence in the UK of breeding aegypti mosquito – the main spreader of dengue, chikungunya and Zika’ with an image of an aegypti mosquito on a person’s skin.

First evidence in the UK of breeding aegypti mosquito – the main spreader of dengue, chikungunya and Zika.

Dr Marcus Blagrove writes for The Conversation highlighting the need for enhanced mosquito surveillance and proactive strategies to mitigate future risks.

bit.ly/3KKlGQP

#TeamLivUni

Something not so sciencey… off to Barcelona next week to screen a documentary my partner has produced and I’m excited!

Any Nick Garrie fans? 🎸🎥

The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes VAD is a Viral AlphaFold Database of protein monomers and homodimers from viruses infecting hosts across the tree of life.

Viral AlphaFold Database (VAD) is live in Science Advances

~27,000 predicted viral protein monomers & homodimers

Conserved folds across bacteria, archaea & eukaryotic viruses

New toxin–antitoxin system KreTA uncovered

Vast “functional darkness” remains uncharted

www.science.org/doi/10.1126/...

Image shows a background with the United Kingdom flag with a vaccine in the foreground.

Following recent decisions by pharmaceutical companies to scale back investment, the UK Parliament’s Science, Innovation and Technology Committee is seeking written evidence on the competitiveness of the UK’s life sciences sector.

Full thread will come later, but @annacusco.bsky.social's preprint on the dog pet gut microbiome is out!

Using ONT+Illumina, we get better MAGs than to corresponding species representative in public databases

doi.org/10.1101/2025...

Report highlights disconnect between data collection and action on EDI in UK science and tech sector A year-long project on Equality, Diversity and Inclusion (EDI) strategies in the UK’s science sector – led by the All-Party Parliamentary Group on Diversity and Inclusion in STEM – has drawn to a clos...

Our year-long project on Equality, Diversity and Inclusion (#EDI) strategies in the UK’s science and tech sectors has drawn to a close with a new report exploring data collection, analysis and insight.

Read our findings and recommendations >>

www.britishscienceassociation.org/News/report-...

Is there anyone here at one of the universities in Wellington, NZ, who would want to host me to give a talk around November 10th?

✨ RNA Modifications Newsletter – September 15, 2025 issue #3

🧬 Fresh RNA modifications newsletter out now: viral tRNA hijacking, hidden rRNA mods, dynamic Ψ, antibiotic resistance & more.

👉 open.substack.com/pub/rnamodif...

#RNAsky #Epitranscriptomics #microsky #ribosome

We are still buzzing from our show! Here’s some snaps of what you missed… in case you were wondering….

Huge thank you to the whole production team and the people who made this happen!

@microbiologysociety.org @britsciassoc.bsky.social @emmottlab.bsky.social @livuninews.bsky.social
#BSF25

Antiviral roller skating! | British Science Festival 2025 - Unity Theatre Run time: 18.30 – 19:15 Throwback: it’s summer 2020, lockdowns are looming, you’ve bought yourself a pair of roller skates to cure your boredom… Swoop over to see the Liverpool Roller Birds dance agai...

The British science festival 2025 has started in Liverpool and @idb-virology.bsky.social and the team are looking forward to welcoming visitors to the Unity theatre this evening for some antiviral roller skating! @antiviral-rskating.bsky.social www.unitytheatreliverpool.co.uk/whats-on/ant...

Girl wearing white t-shirt waving a yellow ribbon

Liverpool Roller birds logo

Looking forward to @antiviral-rskating.bsky.social this evening @unitytheatre.bsky.social! In partnership with Liverpool Roller Birds, a team from @livunihls.bsky.social will demonstrate how antivirals are designed... on wheels! Book your tickets now! bit.ly/46jQ4Zs. #BSF25
Photo: @reebeesnaps

TODAY! #BSF25

I‘m on social media duty today 😇
Keep your eyes peeled for updates… and if you’re free and in Liverpool… come to the show!!!

#BSF25

Happy DAY 1 of the British Science Festival to all who celebrate! What activity are you kicking it off with? 🤩🧬🦠🧪🔭🔬🥼🧫🔭⚗️!! #BSF25 #scicomm #microsky #sciart

that also means its just TWO DAYS until ✨️🦠🛼Antiviral Roller Skating🛼🦠✨️ hits the stage @unitytheatre.bsky.social Tickets still available!

THIS WEEK!!!!!

Come learn about viruses 🦠😍

@antiviral-rskating.bsky.social
@livuni-ismib.bsky.social
@livuni-ives.bsky.social
@britsciassoc.bsky.social

Lysosomal RNA profiling reveals targeting of specific types of RNAs for degradation Autophagy targets a wide variety of substrates for degradation within lysosomes. While lysosomes are known to possess RNase activity, the role of lysosomal RNA degradation in post-transcriptional gene...

I am excited to share my graduate work in the Sabatini and @bartellab.bsky.social labs. Since their discovery, we have known lysosomes possess RNase activity; however, their substrates were not known. Surprisingly we find specific RNAs are targeted for degradation! www.biorxiv.org/content/10.1...

Human RNome Project Our mission is to advance RNA science to impact human health, food security and boost biomanufacturing.

The human RNome project meeting report is now live!

Prepared by myself and fellow ECRs @bennetthenzeler.bsky.social and @ramibechara.bsky.social

Check it out 🧬

humanrnomeproject.org/2025-worksho...

#RNAmodifications #MassSpec #nanopore

CoBRA: Compound Binding Site Prediction using RNA Language Model Ribonucleic acid (RNA) molecules perform a variety of functions within cells and thus implicated in various human diseases such as cancer. The fact that the proteins constitute a small portion of mRNA...

CoBRA: Compound Binding Site Prediction using RNA Language Model
doi.org/10.1101/2025...

🛼 BSF25 presents Antiviral Roller Skating!

Explore viruses & immunity through science + skating fun @liverpooluni.bsky.social

Fri 12 Sept
18.30 - 19:15
Unity Theatre - Unity One

@britsciassoc.bsky.social

Free/Book now 👉

britishscienceassociation-tickets.ticketsolve.com/ticketbooth/...

Graphic of roller-skaters in front of a coronavirus

Antiviral roller skating! It's the sports / science crossover event we've been waiting for! Part of British Science Festival, Liverpool Roller Birds will show you just what Coronavirus can do, and how science stops it. 12 Sept britishscienceassociation-tickets.ticketsolve.com/ticketbooth/... #BSF25

Greyscale virus background with a photo in a lilac border in the middle showing Debs waving a yellow ribbon emphatically whilst three other skaters, Elle, Helen and Hannah (left to right) in the background giggles. A white speech bubble from Hannah is in the top right saying "She's at it with the ribbon again. guys"

Greyscale virus background with a photo in a purple border with Hannah, wearing all black, laughing and holding a purple and a yellow ribbon in each hand. Lynn is in the background laughing with her hand over her mouth. A white speech bubble is coming from Hannah saying "Oh wait, guys, aive seen the light. Ribbon joy forever!"

A greyscale background with Debs and Imogen both smiling with their eyes closed and hands on their hips, facing each other. 3 purple cartoon viruses are dotted around the photo and a white text bubble coming from Imogen says "wow, can't believe we get to have so much fun learning about viruses & antivirals!" Beneath the photo it says "this could be you at..." followed by a lilac and white sketch style arrow pointing right to the next slide.

A greyscale background with a photo of Ani leading the choreography of a group of five skaters holding hands in a circle. The text above the photo reads "Antiviral Roller Skating @ British Science Festival 2025. Below the photo the text reads "Friday 12th September, 18:30, Unity Theatre - Theatre One

Just over ONE WEEK to go and things are really coming together!
Here's a look at some fun we've been having preparing for #BSF25 next week! 🎀🧬🦠✨️
📸: @rebee.bsky.social

@britsciassoc.bsky.social
@livuninews.bsky.social
@microbiologysociety.bsky.social

#scicomm
#rollerderby
#rollerskating

‘Almost unimaginable’: these ants are different species but share a mother Ant queens of one species clone ants of another to create hybrid workers that do their bidding.

woah this is genuinely, utterly WILD

Ant queens of one species produce males of another species, so she can then mate with them and produce hybrid workers!

This is so gloriously weird I can't quite compute it 🤯🧪🐜
www.nature.com/articles/d41...